Click here to switch to the map view.

The map label for this gene is rnpA

Identifier: 110632736

GI number: 110632736

Start: 417908

End: 418270

Strand: Direct

Name: rnpA

Synonym: Meso_0375

Alternate gene names: 110632736

Gene position: 417908-418270 (Clockwise)

Preceding gene: 110632735

Following gene: 110632737

Centisome position: 9.47

GC content: 65.84

Gene sequence:

>363_bases
GTGTCTGGCCGAGCGCAGAGGCAGCACCCGGGGCGGCTCACCAAGCGCGCCGAATTTCTGGCGGTCCAGCGCGGCTTAAA
GTTGCGTGGACGGCTTTTTCTGCTCGAACTGCTGGCGCGCGGGGATGACGATCCGCCGCGCGTGGGCATTACGGTGACCA
AAAAGGTCGGCAACGCGGTCGAGCGAAACCGCATTCGCCGCCGGCTGCGCGAAGCGGTTCGCGTGCATGCGGCCGATGAC
ATGGCGACCGGCACTGACTATGTGATCGTCGGAAGGCGCGAAATCTTGGACGCGCCGTTCGGAGCGCTGAAGGACGAGCT
TTCCCGGCGCATCCGCGGGAACAAACCCGCTCGCACGGGCTAA

Upstream 100 bases:

>100_bases
CGCGCGCATGGCGACCAAAGGCGGCCGCGGCGTGATCGCTGCCCGCCGCAACCGTGGCCGCAAGCGGCTGTCCGCCTGAG
GTCCGGTGGGGCCGGGGGCG

Downstream 100 bases:

>100_bases
GGAAACTGATGGAAAACAATCGCAATCTCCTCATCACAATCGCGCTGTCGGTGGTTATCCTGACGCTTTGGCAGGTGTTC
TACGTCAACCCGCGCGTCGA

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 120; Mature: 119

Protein sequence:

>120_residues
MSGRAQRQHPGRLTKRAEFLAVQRGLKLRGRLFLLELLARGDDDPPRVGITVTKKVGNAVERNRIRRRLREAVRVHAADD
MATGTDYVIVGRREILDAPFGALKDELSRRIRGNKPARTG

Sequences:

>Translated_120_residues
MSGRAQRQHPGRLTKRAEFLAVQRGLKLRGRLFLLELLARGDDDPPRVGITVTKKVGNAVERNRIRRRLREAVRVHAADD
MATGTDYVIVGRREILDAPFGALKDELSRRIRGNKPARTG
>Mature_119_residues
SGRAQRQHPGRLTKRAEFLAVQRGLKLRGRLFLLELLARGDDDPPRVGITVTKKVGNAVERNRIRRRLREAVRVHAADDM
ATGTDYVIVGRREILDAPFGALKDELSRRIRGNKPARTG

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_MESSB (Q11LE6)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_672944.1
- ProteinModelPortal:   Q11LE6
- SMR:   Q11LE6
- STRING:   Q11LE6
- GeneID:   4182053
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0375
- NMPDR:   fig|266779.1.peg.4174
- eggNOG:   COG0594
- HOGENOM:   HBG728160
- OMA:   HDYVIVA
- ProtClustDB:   PRK01313
- BioCyc:   MSP266779:MESO_0375-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13520; Mature: 13389

Theoretical pI: Translated: 12.10; Mature: 12.10

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRAQRQHPGRLTKRAEFLAVQRGLKLRGRLFLLELLARGDDDPPRVGITVTKKVGNAV
CCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHCCHH
ERNRIRRRLREAVRVHAADDMATGTDYVIVGRREILDAPFGALKDELSRRIRGNKPARTG
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SGRAQRQHPGRLTKRAEFLAVQRGLKLRGRLFLLELLARGDDDPPRVGITVTKKVGNAV
CCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHCCHH
ERNRIRRRLREAVRVHAADDMATGTDYVIVGRREILDAPFGALKDELSRRIRGNKPARTG
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA