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The map label for this gene is luxQ [H]

Identifier: 110632701

GI number: 110632701

Start: 378872

End: 381322

Strand: Direct

Name: luxQ [H]

Synonym: Meso_0340

Alternate gene names: 110632701

Gene position: 378872-381322 (Clockwise)

Preceding gene: 110632696

Following gene: 110632703

Centisome position: 8.59

GC content: 62.87

Gene sequence:

>2451_bases
GTGACCACGTTGGAAGCCGCAGAGGCGAAGAGTTTGCCGCGCCATGATCGGCTCGGTGTGCGCGCGCGGCTGTTGCTCGC
CTTCTTTGCAATCGCAGCCTTCGCGGTTTTAGCCGCCGCGGCGGGAATGTACGCTTTCCGCGAGGTCGGCTCACGACTTG
AGGTCATCGATACGCGTGTCCCGCCCACACTCTCGGCGCTCGAACTCTCGCGCTCGGCCGAGCGCATCATCGCCGCGGCG
CCAGCTCTACTTTCGGCAAGCGGGCGGGCGCAGCGAGACGAAGTGAAAGCCGAGCTCGCAGCCGAGGTCGGGCGTTTGAA
CGCGACGCTCGCCCGGCTGAAGCGCGATAGCGCGGGACTGCCGCTGCTTTCGGAAGTCGAGAGGACCGTTTCCTCCCTGG
CCGCCAATCTGGCGGCTCTCGATGAGCTGGTTGCCCGCCGGCTCGTGATAAACGAGCGCATAGGGCTTTTGAGAAGCCGG
GTTTTCCAGATCGAGGGAGAAACGCAGAGATTGCTCGCACCTTGGCTGGAGGTCGTGGGCAGGGAATCCGCGATGCTGGT
CGAGGCAGGCAAGGGCGATCCGACAAGCCAGGCCGGCGGCCCTGAACGGCTCTCGTTCTTGATCGAGTTGCAGCGGCTGA
TGCGAACTGCGCAGGCGCGCGCATCCGCTGCCGCCGACATGCTCATCGAAGCCTCCACCACAAATGAGCCAGCCCGGCTG
CCGGTGCTCGAATTCCAGCTCGGACTTGCTTTCGATGATCTCGCCGAGATCTCCAAACAGTTCGATCCCAGGCTGCGGCC
GCTCTTTCTGGAAGAAATAGCGAAACTGCGCGGACTCGCCCAGGGAGATGAAGCGATCGCCCAGGCTCGCAGCGAGGAAC
TCATGCTTGTCGAACAGGGCGAGGACCTGCTCGCCGAGACCGCCAGGCTATCCTCGCAGCTTGGTGCTGCGATTGACCGG
CTCGGCGATGCGGCCAAGGCAGACATCGGTATGGCGATCCAGGATGCGCTCCTGGTGCAGAGGCAAAGCGCCAGCGCCCT
CGTCCTTCTGGTAGCGCTGAGCCTACTGACCTCGGTGCTGATCGTATGGCTCTATGTGGGAAAAAACATTGTACGCCGCC
TTACCGCGCTAAGTGACGGCATGCTCGCCATCATCCGCGGCAGGCTCGAGACACCTGTAGTCGCGGAGGGGAGTGACGAA
ATCGCGGCTATGGCCCGAGCAGTCGAGGTCTTCCGTCAGAACACGCTGGAGCGCGACAAGCTGCTGTCCGAGAAAGCGCG
AGCGGCCGATCTCCTCGAGCAGGAAGTAAGGCAACGCACGGCCGAACTGGAGACGGCCAACACGTTCAAGTCGCGCTTTC
TCGCCGCCGCAAGCCATGATCTGCGCCAGCCCCTCCACGCGCTGAACCTTTTCATCGCCCAACTGCGCAATGAGGCTGAC
CCGGTCGAGCGCGCGAGATTGGTCGGTCGTATCGATGTCGCGGTGGGATCGGTCAACGAGCTCCTCGAAGCTCTGCTCGA
CATGTCGAAACTGGAGGCAGGCGTGCTTGAGCCGGAGTTCACCGAGTTCCCTGTCAATCACCTCTTCAAGCGCATCGAGA
CGACCTTTGTAGACGCCGCATGCGAGAAGGGGCTTCGACTGATCATCGTCCCAAGCCATGCCTGGGTGCGCAGTGACTTC
GTCCTGCTGGAACGCGTTTTGTTCAACCTTGTGTCGAATGCTGTCCGCTGTACGTCGCGCGGTGGCGTGTTGATCGGCGG
GCGCTTTAGGAGTGGCCAGTTGCGGATAGATGTTTGCGACACAGGTCCAGGTATTCCGGCCGATCAGCAGCAGGCGGTGT
TTGGCGAATTCTACCGGTTGGCCAAGGGGGATAGCAGCGCCGGGCTGGGGCTCGGCCTTGCCATTGTCGACCGGCTCGGG
CGTCTGCTGGACCATAGGGTCGAGCTGAGTTCGCGGCTGAATCGCGGCTCGCGTTTCTCTGTTTCCGTCCCGCTTGCGGC
CAGGCAGCACGGCCTGATCGAAGCATCCGTCACGGATGTGATTTCTGACCCCGCGGCAGGAAAACTGGTGGTGGTCATCG
ATGATGATCCGCTCGTGCTCGAAGGTATGGGCGGGATCCTGCGAAGCTGGGGGTGCCGCGTAGTGGCGGCCCCTTCCGGC
ACGGCCGCGCTCTCGCAGCTTGCGATTGACCGGCATCGGCCGGATCTTATCGTTGCCGATTATCGGCTTGCCGATGGCAG
GACGGGGATCCAGGCGATCAGGCATCTGCGCGAAGGATACGGAGCTGCCATTCCAGCGTTTCTCATCAGCGGCGACACGG
CTCCCGAACGGCTGCGCGATGCTCGTGAGGAAGGCTACCAGCTCTTGCACAAACCGGTGACGCCGATGCGGCTGAGGGCC
ATGCTGAACCAACTCCTGAGGGCAGGAAACGCAACGACGATGGTGCACTAG

Upstream 100 bases:

>100_bases
AGAACATCCCTGCGTCGCATCGAAGGCCTCCATTTTGCTGCAACGCTTCTTTCAGCCTTGTGCTAATTTTAGCACGAAAA
CGCGCGAGAGTGGTTTGGCT

Downstream 100 bases:

>100_bases
AACCAGGCGGCTATCCGGCTATCTTACGTCGCCGTGCCCGAGAGCGCTGGCCGCGATCACCGCCTCGGTGCGGTTTGAGA
CCTTCAGCGCCTTTAGTATG

Product: periplasmic sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 816; Mature: 815

Protein sequence:

>816_residues
MTTLEAAEAKSLPRHDRLGVRARLLLAFFAIAAFAVLAAAAGMYAFREVGSRLEVIDTRVPPTLSALELSRSAERIIAAA
PALLSASGRAQRDEVKAELAAEVGRLNATLARLKRDSAGLPLLSEVERTVSSLAANLAALDELVARRLVINERIGLLRSR
VFQIEGETQRLLAPWLEVVGRESAMLVEAGKGDPTSQAGGPERLSFLIELQRLMRTAQARASAAADMLIEASTTNEPARL
PVLEFQLGLAFDDLAEISKQFDPRLRPLFLEEIAKLRGLAQGDEAIAQARSEELMLVEQGEDLLAETARLSSQLGAAIDR
LGDAAKADIGMAIQDALLVQRQSASALVLLVALSLLTSVLIVWLYVGKNIVRRLTALSDGMLAIIRGRLETPVVAEGSDE
IAAMARAVEVFRQNTLERDKLLSEKARAADLLEQEVRQRTAELETANTFKSRFLAAASHDLRQPLHALNLFIAQLRNEAD
PVERARLVGRIDVAVGSVNELLEALLDMSKLEAGVLEPEFTEFPVNHLFKRIETTFVDAACEKGLRLIIVPSHAWVRSDF
VLLERVLFNLVSNAVRCTSRGGVLIGGRFRSGQLRIDVCDTGPGIPADQQQAVFGEFYRLAKGDSSAGLGLGLAIVDRLG
RLLDHRVELSSRLNRGSRFSVSVPLAARQHGLIEASVTDVISDPAAGKLVVVIDDDPLVLEGMGGILRSWGCRVVAAPSG
TAALSQLAIDRHRPDLIVADYRLADGRTGIQAIRHLREGYGAAIPAFLISGDTAPERLRDAREEGYQLLHKPVTPMRLRA
MLNQLLRAGNATTMVH

Sequences:

>Translated_816_residues
MTTLEAAEAKSLPRHDRLGVRARLLLAFFAIAAFAVLAAAAGMYAFREVGSRLEVIDTRVPPTLSALELSRSAERIIAAA
PALLSASGRAQRDEVKAELAAEVGRLNATLARLKRDSAGLPLLSEVERTVSSLAANLAALDELVARRLVINERIGLLRSR
VFQIEGETQRLLAPWLEVVGRESAMLVEAGKGDPTSQAGGPERLSFLIELQRLMRTAQARASAAADMLIEASTTNEPARL
PVLEFQLGLAFDDLAEISKQFDPRLRPLFLEEIAKLRGLAQGDEAIAQARSEELMLVEQGEDLLAETARLSSQLGAAIDR
LGDAAKADIGMAIQDALLVQRQSASALVLLVALSLLTSVLIVWLYVGKNIVRRLTALSDGMLAIIRGRLETPVVAEGSDE
IAAMARAVEVFRQNTLERDKLLSEKARAADLLEQEVRQRTAELETANTFKSRFLAAASHDLRQPLHALNLFIAQLRNEAD
PVERARLVGRIDVAVGSVNELLEALLDMSKLEAGVLEPEFTEFPVNHLFKRIETTFVDAACEKGLRLIIVPSHAWVRSDF
VLLERVLFNLVSNAVRCTSRGGVLIGGRFRSGQLRIDVCDTGPGIPADQQQAVFGEFYRLAKGDSSAGLGLGLAIVDRLG
RLLDHRVELSSRLNRGSRFSVSVPLAARQHGLIEASVTDVISDPAAGKLVVVIDDDPLVLEGMGGILRSWGCRVVAAPSG
TAALSQLAIDRHRPDLIVADYRLADGRTGIQAIRHLREGYGAAIPAFLISGDTAPERLRDAREEGYQLLHKPVTPMRLRA
MLNQLLRAGNATTMVH
>Mature_815_residues
TTLEAAEAKSLPRHDRLGVRARLLLAFFAIAAFAVLAAAAGMYAFREVGSRLEVIDTRVPPTLSALELSRSAERIIAAAP
ALLSASGRAQRDEVKAELAAEVGRLNATLARLKRDSAGLPLLSEVERTVSSLAANLAALDELVARRLVINERIGLLRSRV
FQIEGETQRLLAPWLEVVGRESAMLVEAGKGDPTSQAGGPERLSFLIELQRLMRTAQARASAAADMLIEASTTNEPARLP
VLEFQLGLAFDDLAEISKQFDPRLRPLFLEEIAKLRGLAQGDEAIAQARSEELMLVEQGEDLLAETARLSSQLGAAIDRL
GDAAKADIGMAIQDALLVQRQSASALVLLVALSLLTSVLIVWLYVGKNIVRRLTALSDGMLAIIRGRLETPVVAEGSDEI
AAMARAVEVFRQNTLERDKLLSEKARAADLLEQEVRQRTAELETANTFKSRFLAAASHDLRQPLHALNLFIAQLRNEADP
VERARLVGRIDVAVGSVNELLEALLDMSKLEAGVLEPEFTEFPVNHLFKRIETTFVDAACEKGLRLIIVPSHAWVRSDFV
LLERVLFNLVSNAVRCTSRGGVLIGGRFRSGQLRIDVCDTGPGIPADQQQAVFGEFYRLAKGDSSAGLGLGLAIVDRLGR
LLDHRVELSSRLNRGSRFSVSVPLAARQHGLIEASVTDVISDPAAGKLVVVIDDDPLVLEGMGGILRSWGCRVVAAPSGT
AALSQLAIDRHRPDLIVADYRLADGRTGIQAIRHLREGYGAAIPAFLISGDTAPERLRDAREEGYQLLHKPVTPMRLRAM
LNQLLRAGNATTMVH

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=347, Percent_Identity=26.5129682997118, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=30.7377049180328, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1788713, Length=372, Percent_Identity=27.1505376344086, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87081816, Length=827, Percent_Identity=26.602176541717, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789149, Length=288, Percent_Identity=30.9027777777778, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786912, Length=281, Percent_Identity=30.6049822064057, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=311, Percent_Identity=26.3665594855305, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=28.4552845528455, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=205, Percent_Identity=30.2439024390244, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=25.4166666666667, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88500; Mature: 88369

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLEAAEAKSLPRHDRLGVRARLLLAFFAIAAFAVLAAAAGMYAFREVGSRLEVIDTRV
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
PPTLSALELSRSAERIIAAAPALLSASGRAQRDEVKAELAAEVGRLNATLARLKRDSAGL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLLSEVERTVSSLAANLAALDELVARRLVINERIGLLRSRVFQIEGETQRLLAPWLEVVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
RESAMLVEAGKGDPTSQAGGPERLSFLIELQRLMRTAQARASAAADMLIEASTTNEPARL
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
PVLEFQLGLAFDDLAEISKQFDPRLRPLFLEEIAKLRGLAQGDEAIAQARSEELMLVEQG
CEEHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECC
EDLLAETARLSSQLGAAIDRLGDAAKADIGMAIQDALLVQRQSASALVLLVALSLLTSVL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IVWLYVGKNIVRRLTALSDGMLAIIRGRLETPVVAEGSDEIAAMARAVEVFRQNTLERDK
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
LLSEKARAADLLEQEVRQRTAELETANTFKSRFLAAASHDLRQPLHALNLFIAQLRNEAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVERARLVGRIDVAVGSVNELLEALLDMSKLEAGVLEPEFTEFPVNHLFKRIETTFVDAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHH
CEKGLRLIIVPSHAWVRSDFVLLERVLFNLVSNAVRCTSRGGVLIGGRFRSGQLRIDVCD
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEECCCEEEEEEEC
TGPGIPADQQQAVFGEFYRLAKGDSSAGLGLGLAIVDRLGRLLDHRVELSSRLNRGSRFS
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VSVPLAARQHGLIEASVTDVISDPAAGKLVVVIDDDPLVLEGMGGILRSWGCRVVAAPSG
EECCHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHCCCEEEECCCC
TAALSQLAIDRHRPDLIVADYRLADGRTGIQAIRHLREGYGAAIPAFLISGDTAPERLRD
HHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
AREEGYQLLHKPVTPMRLRAMLNQLLRAGNATTMVH
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTLEAAEAKSLPRHDRLGVRARLLLAFFAIAAFAVLAAAAGMYAFREVGSRLEVIDTRV
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
PPTLSALELSRSAERIIAAAPALLSASGRAQRDEVKAELAAEVGRLNATLARLKRDSAGL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLLSEVERTVSSLAANLAALDELVARRLVINERIGLLRSRVFQIEGETQRLLAPWLEVVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
RESAMLVEAGKGDPTSQAGGPERLSFLIELQRLMRTAQARASAAADMLIEASTTNEPARL
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
PVLEFQLGLAFDDLAEISKQFDPRLRPLFLEEIAKLRGLAQGDEAIAQARSEELMLVEQG
CEEHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECC
EDLLAETARLSSQLGAAIDRLGDAAKADIGMAIQDALLVQRQSASALVLLVALSLLTSVL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IVWLYVGKNIVRRLTALSDGMLAIIRGRLETPVVAEGSDEIAAMARAVEVFRQNTLERDK
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
LLSEKARAADLLEQEVRQRTAELETANTFKSRFLAAASHDLRQPLHALNLFIAQLRNEAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVERARLVGRIDVAVGSVNELLEALLDMSKLEAGVLEPEFTEFPVNHLFKRIETTFVDAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHH
CEKGLRLIIVPSHAWVRSDFVLLERVLFNLVSNAVRCTSRGGVLIGGRFRSGQLRIDVCD
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEECCCEEEEEEEC
TGPGIPADQQQAVFGEFYRLAKGDSSAGLGLGLAIVDRLGRLLDHRVELSSRLNRGSRFS
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VSVPLAARQHGLIEASVTDVISDPAAGKLVVVIDDDPLVLEGMGGILRSWGCRVVAAPSG
EECCHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHCCCEEEECCCC
TAALSQLAIDRHRPDLIVADYRLADGRTGIQAIRHLREGYGAAIPAFLISGDTAPERLRD
HHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
AREEGYQLLHKPVTPMRLRAMLNQLLRAGNATTMVH
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA