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The map label for this gene is arsC [H]

Identifier: 110632685

GI number: 110632685

Start: 360060

End: 360485

Strand: Reverse

Name: arsC [H]

Synonym: Meso_0324

Alternate gene names: 110632685

Gene position: 360485-360060 (Counterclockwise)

Preceding gene: 110632686

Following gene: 110632684

Centisome position: 8.17

GC content: 62.91

Gene sequence:

>426_bases
ATGGACATTATCATCTATCACAATCCCGGTTGCGGCACCTCGCGCAATACGCTGGCAATGATCAGGAACGCAGGCGTGGA
GCCGCATATTGTCGAGTATCTGAAAACACCGCCTTCGCGCGTCATGCTCGAGACGCTGATTGCGCGCATGGGCATCCCGG
TTCGCGCGCTCCTCCGGCAGAAAGGCACGCCCTATGCCGAACTCGGGCTGGGCGATGCAAGCCTGACGGACGAACAACTG
CTCGATGCCATGATGGCCCATCCGGTCCTGATCAACCGGCCGATCGTCGTGAGCCCCAAGGGCGTGCGGCTCTGCCGTCC
GTCGGAAGAAGTGCTCGCCCTGCTCCCACCGCAGCGGGGCGAATTCGTCAAGGAAGACGGCGAGCGCGTGGTGGACGAGC
ACGGCCGCCGCATCGCGACTGCATAA

Upstream 100 bases:

>100_bases
ATCGGCAGCATCGACAAGTTGGCGCTCGGCACCAGGCTTGTCGAGATCGGGCAATTGCAGGGCGCAACGAAGCCGCGTCC
GAGCGCGGCTTGAGGCGAAG

Downstream 100 bases:

>100_bases
GGAAACCGCATGTCCACCTTCGAACGTTATCTGACCCTCTGGGTCGCCTTGTGCATCGTCGCGGGCATTGCGCTGGGCCA
CGGCATGCCCGGCGTTTTCG

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MDIIIYHNPGCGTSRNTLAMIRNAGVEPHIVEYLKTPPSRVMLETLIARMGIPVRALLRQKGTPYAELGLGDASLTDEQL
LDAMMAHPVLINRPIVVSPKGVRLCRPSEEVLALLPPQRGEFVKEDGERVVDEHGRRIATA

Sequences:

>Translated_141_residues
MDIIIYHNPGCGTSRNTLAMIRNAGVEPHIVEYLKTPPSRVMLETLIARMGIPVRALLRQKGTPYAELGLGDASLTDEQL
LDAMMAHPVLINRPIVVSPKGVRLCRPSEEVLALLPPQRGEFVKEDGERVVDEHGRRIATA
>Mature_141_residues
MDIIIYHNPGCGTSRNTLAMIRNAGVEPHIVEYLKTPPSRVMLETLIARMGIPVRALLRQKGTPYAELGLGDASLTDEQL
LDAMMAHPVLINRPIVVSPKGVRLCRPSEEVLALLPPQRGEFVKEDGERVVDEHGRRIATA

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=138, Percent_Identity=64.4927536231884, Blast_Score=184, Evalue=2e-48,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=44.7368421052632, Blast_Score=100, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15541; Mature: 15541

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIIYHNPGCGTSRNTLAMIRNAGVEPHIVEYLKTPPSRVMLETLIARMGIPVRALLRQ
CEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
KGTPYAELGLGDASLTDEQLLDAMMAHPVLINRPIVVSPKGVRLCRPSEEVLALLPPQRG
CCCCHHHCCCCCCCCCHHHHHHHHHHCCEECCCCEEECCCCCEEECCHHHHEEECCCCCC
EFVKEDGERVVDEHGRRIATA
CHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure
MDIIIYHNPGCGTSRNTLAMIRNAGVEPHIVEYLKTPPSRVMLETLIARMGIPVRALLRQ
CEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
KGTPYAELGLGDASLTDEQLLDAMMAHPVLINRPIVVSPKGVRLCRPSEEVLALLPPQRG
CCCCHHHCCCCCCCCCHHHHHHHHHHCCEECCCCEEECCCCCEEECCHHHHEEECCCCCC
EFVKEDGERVVDEHGRRIATA
CHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]