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The map label for this gene is arsC [H]

Identifier: 110632686

GI number: 110632686

Start: 360493

End: 361020

Strand: Reverse

Name: arsC [H]

Synonym: Meso_0325

Alternate gene names: 110632686

Gene position: 361020-360493 (Counterclockwise)

Preceding gene: 110632687

Following gene: 110632685

Centisome position: 8.18

GC content: 62.12

Gene sequence:

>528_bases
ATGATTGAACGCGTCTACAATGTCCTGTTTCTCTGCACCGGAAATTCCGCCCGCTCGATCCTGGCAGAGAGCATCCTTAC
GAAAGATGGCCGCGGGCGCTTTCGCGCTTTCTCCGCCGGCAGCCGTCCCAAGGGAGCCGTCAATCCCTTTGCGCTGAAGG
TGCTCAGGAGCTTCGACTATCCAGCTGAGGGCTTCAGGTCGAAAAACTGGGAGGAGTTCGCCGCGCCCGACGCCCCGTTG
ATGGATTTCGTGTTCACCGTCTGCGACAATGCCGCCGGCGAGGCCTGCCCCGTATGGCCCGGCCAGCCGATGACGGCGCA
TTGGGGGATAGAGGATCCGGCGGCCGCCGAAGGCCCGGACATTCAAAAGGAAGCCGCCTTCGTCACCGCTTTCCGCCACC
TCAAGAACCGGATCTCCATCTTTACGGCATTGCCTATCGGCAGCATCGACAAGTTGGCGCTCGGCACCAGGCTTGTCGAG
ATCGGGCAATTGCAGGGCGCAACGAAGCCGCGTCCGAGCGCGGCTTGA

Upstream 100 bases:

>100_bases
AAGGATTGCTGCGGCGGGCGGCCCGAGATATGCGCGCCGCTGATCGCCGAACTTTCACCTTGTTGTCCACCTGCCATGAC
TGCAGCCAAGGAGGCTGCCC

Downstream 100 bases:

>100_bases
GGCGAAGATGGACATTATCATCTATCACAATCCCGGTTGCGGCACCTCGCGCAATACGCTGGCAATGATCAGGAACGCAG
GCGTGGAGCCGCATATTGTC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MIERVYNVLFLCTGNSARSILAESILTKDGRGRFRAFSAGSRPKGAVNPFALKVLRSFDYPAEGFRSKNWEEFAAPDAPL
MDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAAEGPDIQKEAAFVTAFRHLKNRISIFTALPIGSIDKLALGTRLVE
IGQLQGATKPRPSAA

Sequences:

>Translated_175_residues
MIERVYNVLFLCTGNSARSILAESILTKDGRGRFRAFSAGSRPKGAVNPFALKVLRSFDYPAEGFRSKNWEEFAAPDAPL
MDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAAEGPDIQKEAAFVTAFRHLKNRISIFTALPIGSIDKLALGTRLVE
IGQLQGATKPRPSAA
>Mature_175_residues
MIERVYNVLFLCTGNSARSILAESILTKDGRGRFRAFSAGSRPKGAVNPFALKVLRSFDYPAEGFRSKNWEEFAAPDAPL
MDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAAEGPDIQKEAAFVTAFRHLKNRISIFTALPIGSIDKLALGTRLVE
IGQLQGATKPRPSAA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18968; Mature: 18968

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIERVYNVLFLCTGNSARSILAESILTKDGRGRFRAFSAGSRPKGAVNPFALKVLRSFDY
CHHHHEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
PAEGFRSKNWEEFAAPDAPLMDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAAEGPD
CHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCC
IQKEAAFVTAFRHLKNRISIFTALPIGSIDKLALGTRLVEIGQLQGATKPRPSAA
CHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIERVYNVLFLCTGNSARSILAESILTKDGRGRFRAFSAGSRPKGAVNPFALKVLRSFDY
CHHHHEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
PAEGFRSKNWEEFAAPDAPLMDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAAEGPD
CHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCC
IQKEAAFVTAFRHLKNRISIFTALPIGSIDKLALGTRLVEIGQLQGATKPRPSAA
CHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]