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The map label for this gene is gntK [H]

Identifier: 110632677

GI number: 110632677

Start: 351707

End: 352231

Strand: Direct

Name: gntK [H]

Synonym: Meso_0316

Alternate gene names: 110632677

Gene position: 351707-352231 (Clockwise)

Preceding gene: 110632673

Following gene: 110632680

Centisome position: 7.97

GC content: 61.71

Gene sequence:

>525_bases
TTGGAAAACTCGACGCCCCCGGCGGTGATTATGGGTGTGGCAGGAAGCGGGAAAACTGTCATCGGTTCCGCACTCGCCGA
AGCGCTTGGTGTTGCCTTTATAGAGGGGGATGACCTTCATCCACCGGAAAATGTCGCCAAGATGGCCAGTGGACAGCCGC
TGACCGACGAGGACCGGATAGGCTGGCTTGACGCCGTCGGCCGCGCCATTGCCGAAAACCGCCGCCCGGCGGGCGGCGCG
GTTACCGCCTGCTCCGCTCTCAAGCGTTCCTACCGCGACCAGTTGCGGCGCCTTAATCCCTCTCTCGTTTTCATTTACCT
GGCGATCAACCCGGATACGGCGCGCATTCGCGTTACGAATCGCAAGGGGCACTTCATGCCGCCGACGCTCGTCGCAAGCC
AGTTCGCTGCCCTGGAGCAGCCCGGCGATGATGAGGCCGCCTTCACGCTGAACGGATTGAGCCCCATAGATGAACTGGTC
GAGGCGGCCGCTGAGCTTTTAAGAAAGCAAAGTGGCGCAAGCTGA

Upstream 100 bases:

>100_bases
GGAAAAGCTCGATCCGGTGCACCTTCCGATAGGTTGGAGAAGGCTCCTGCGTTCTCTATGATGCGAATCTAACTCTCTCG
GGAGGAGGAGCGGAGGAGCT

Downstream 100 bases:

>100_bases
GTGCGCCATTTGCCGCTGGCAGAGGTTGCGCGCGAAAGCCTCCAGCCACGAGAAACGTCACCTGCGCTTGAACGCTTCCG
CGAGTGCCGCGCCGAGAGCG

Product: carbohydrate kinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MENSTPPAVIMGVAGSGKTVIGSALAEALGVAFIEGDDLHPPENVAKMASGQPLTDEDRIGWLDAVGRAIAENRRPAGGA
VTACSALKRSYRDQLRRLNPSLVFIYLAINPDTARIRVTNRKGHFMPPTLVASQFAALEQPGDDEAAFTLNGLSPIDELV
EAAAELLRKQSGAS

Sequences:

>Translated_174_residues
MENSTPPAVIMGVAGSGKTVIGSALAEALGVAFIEGDDLHPPENVAKMASGQPLTDEDRIGWLDAVGRAIAENRRPAGGA
VTACSALKRSYRDQLRRLNPSLVFIYLAINPDTARIRVTNRKGHFMPPTLVASQFAALEQPGDDEAAFTLNGLSPIDELV
EAAAELLRKQSGAS
>Mature_174_residues
MENSTPPAVIMGVAGSGKTVIGSALAEALGVAFIEGDDLHPPENVAKMASGQPLTDEDRIGWLDAVGRAIAENRRPAGGA
VTACSALKRSYRDQLRRLNPSLVFIYLAINPDTARIRVTNRKGHFMPPTLVASQFAALEQPGDDEAAFTLNGLSPIDELV
EAAAELLRKQSGAS

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=182, Percent_Identity=36.2637362637363, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI87082265, Length=162, Percent_Identity=42.5925925925926, Blast_Score=140, Evalue=3e-35,
Organism=Escherichia coli, GI1790719, Length=137, Percent_Identity=46.7153284671533, Blast_Score=135, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25146487, Length=165, Percent_Identity=43.6363636363636, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320454, Length=145, Percent_Identity=40.6896551724138, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18363; Mature: 18363

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSTPPAVIMGVAGSGKTVIGSALAEALGVAFIEGDDLHPPENVAKMASGQPLTDEDRI
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHCCCCCCCCCCC
GWLDAVGRAIAENRRPAGGAVTACSALKRSYRDQLRRLNPSLVFIYLAINPDTARIRVTN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEC
RKGHFMPPTLVASQFAALEQPGDDEAAFTLNGLSPIDELVEAAAELLRKQSGAS
CCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MENSTPPAVIMGVAGSGKTVIGSALAEALGVAFIEGDDLHPPENVAKMASGQPLTDEDRI
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHCCCCCCCCCCC
GWLDAVGRAIAENRRPAGGAVTACSALKRSYRDQLRRLNPSLVFIYLAINPDTARIRVTN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEC
RKGHFMPPTLVASQFAALEQPGDDEAAFTLNGLSPIDELVEAAAELLRKQSGAS
CCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]