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The map label for this gene is minC [H]

Identifier: 110632680

GI number: 110632680

Start: 355873

End: 356679

Strand: Direct

Name: minC [H]

Synonym: Meso_0319

Alternate gene names: 110632680

Gene position: 355873-356679 (Clockwise)

Preceding gene: 110632677

Following gene: 110632681

Centisome position: 8.07

GC content: 59.98

Gene sequence:

>807_bases
ATGGGATGCGAGCGCATTAACCATTCGTTAACCTGGGATAGCATAGACCCGAGCAACCAAAAATTAACCAAGATCACCAA
AGTGCTAACCGATTCCCGACCGATCCGTCTCAAGGGGCGTTCCTTTCTTGCGCTCACTCTCACGCCTGAGCTGCCGCTGG
AGGGGTGGCTGGCGCGGCTGGATGATCTCGCCTCGCGATCTGCCGGCTTTTTCCTGCGCAAGCCCGTCGTGCTTGATGTC
GAGGGACTGGAGATAGATCGGGCGCGGCTGAAGGAACTCATCGACGAGCTTGGAAGGCGCGGCGTCCGGATTATGGGACT
GGAAGGTGCGCGTGCGTCTCAGTTAGGTGCCGATATGCCGCCTCCAATGGCGGGAGGCCGGCCCGGCCCAGATTTCGAAG
CACCGCTTTCGGATCCGGGAGCCAATCCGGAAAAGCCCTTAGCTTCCGTTTCGCCGCCCGAACCGCAACCCGTGAGGACA
CCTTCCATCATTGTCAATCGGCCCGTGCGCTCCGGGCAATCGGTGATTTTCACGGAAGGGGATGTGACCGTCATCGGATC
AGTCGCATCCGGTGCGGAGATCGTGGCGGGCGGTTCGATCCATATCTACGGAGCTTTGCGGGGTCGGGCGCTGGCAGGTT
CCATGGGCGATAGCTCTGCTCGCATCTTTTGCCGCAAGCTCGAAGCAGAGCTCCTCGCAATCGATGGTCTCTACAAGACG
GCCGATGATATCGAGCCGCAATTCCACGGGCGAGCGGTTCAGCTCTGGCTCGAAGGTGATTCAATCATGGCGGAGGCGCT
CGTCTGA

Upstream 100 bases:

>100_bases
GGGCTGATCCCGGTTAGCGAGGCCAGCTGCCTCGCCGGGCGGCGCGATTTGCCGGTGCCGTCCACAAGAAATCGCGCTTT
TTCAGCTCGGATCTTCCGCA

Downstream 100 bases:

>100_bases
GCCGGTTCACCCGGCCAGGAGACCAGGAGAGGGAAATGGGTAAAGTCATTGTTGTTACTTCAGGCAAGGGCGGCGTCGGC
AAGACGACGTCGACAGCCGC

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MGCERINHSLTWDSIDPSNQKLTKITKVLTDSRPIRLKGRSFLALTLTPELPLEGWLARLDDLASRSAGFFLRKPVVLDV
EGLEIDRARLKELIDELGRRGVRIMGLEGARASQLGADMPPPMAGGRPGPDFEAPLSDPGANPEKPLASVSPPEPQPVRT
PSIIVNRPVRSGQSVIFTEGDVTVIGSVASGAEIVAGGSIHIYGALRGRALAGSMGDSSARIFCRKLEAELLAIDGLYKT
ADDIEPQFHGRAVQLWLEGDSIMAEALV

Sequences:

>Translated_268_residues
MGCERINHSLTWDSIDPSNQKLTKITKVLTDSRPIRLKGRSFLALTLTPELPLEGWLARLDDLASRSAGFFLRKPVVLDV
EGLEIDRARLKELIDELGRRGVRIMGLEGARASQLGADMPPPMAGGRPGPDFEAPLSDPGANPEKPLASVSPPEPQPVRT
PSIIVNRPVRSGQSVIFTEGDVTVIGSVASGAEIVAGGSIHIYGALRGRALAGSMGDSSARIFCRKLEAELLAIDGLYKT
ADDIEPQFHGRAVQLWLEGDSIMAEALV
>Mature_267_residues
GCERINHSLTWDSIDPSNQKLTKITKVLTDSRPIRLKGRSFLALTLTPELPLEGWLARLDDLASRSAGFFLRKPVVLDVE
GLEIDRARLKELIDELGRRGVRIMGLEGARASQLGADMPPPMAGGRPGPDFEAPLSDPGANPEKPLASVSPPEPQPVRTP
SIIVNRPVRSGQSVIFTEGDVTVIGSVASGAEIVAGGSIHIYGALRGRALAGSMGDSSARIFCRKLEAELLAIDGLYKTA
DDIEPQFHGRAVQLWLEGDSIMAEALV

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=241, Percent_Identity=33.6099585062241, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C [H]

EC number: NA

Molecular weight: Translated: 28761; Mature: 28630

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGCERINHSLTWDSIDPSNQKLTKITKVLTDSRPIRLKGRSFLALTLTPELPLEGWLARL
CCHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCCEEECCCEEEEEEECCCCCHHHHHHHH
DDLASRSAGFFLRKPVVLDVEGLEIDRARLKELIDELGRRGVRIMGLEGARASQLGADMP
HHHHHCCCCEEEECCEEEEECCCEECHHHHHHHHHHHHHCCEEEEEECCCCHHHCCCCCC
PPMAGGRPGPDFEAPLSDPGANPEKPLASVSPPEPQPVRTPSIIVNRPVRSGQSVIFTEG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECC
DVTVIGSVASGAEIVAGGSIHIYGALRGRALAGSMGDSSARIFCRKLEAELLAIDGLYKT
CEEEEEECCCCCEEEECCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHEEEECCCHHC
ADDIEPQFHGRAVQLWLEGDSIMAEALV
HHHCCCCCCCEEEEEEECCCHHHHHHCC
>Mature Secondary Structure 
GCERINHSLTWDSIDPSNQKLTKITKVLTDSRPIRLKGRSFLALTLTPELPLEGWLARL
CHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCCEEECCCEEEEEEECCCCCHHHHHHHH
DDLASRSAGFFLRKPVVLDVEGLEIDRARLKELIDELGRRGVRIMGLEGARASQLGADMP
HHHHHCCCCEEEECCEEEEECCCEECHHHHHHHHHHHHHCCEEEEEECCCCHHHCCCCCC
PPMAGGRPGPDFEAPLSDPGANPEKPLASVSPPEPQPVRTPSIIVNRPVRSGQSVIFTEG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECC
DVTVIGSVASGAEIVAGGSIHIYGALRGRALAGSMGDSSARIFCRKLEAELLAIDGLYKT
CEEEEEECCCCCEEEECCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHEEEECCCHHC
ADDIEPQFHGRAVQLWLEGDSIMAEALV
HHHCCCCCCCEEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]