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The map label for this gene is ydcR [H]

Identifier: 110632614

GI number: 110632614

Start: 284588

End: 286039

Strand: Reverse

Name: ydcR [H]

Synonym: Meso_0253

Alternate gene names: 110632614

Gene position: 286039-284588 (Counterclockwise)

Preceding gene: 110632619

Following gene: 110632612

Centisome position: 6.48

GC content: 61.85

Gene sequence:

>1452_bases
ATGGAACAGCGTCTCGACCGAACGGCGAATGGCGGCAGGCTGGTCGACATGGTGATGGACGCAGTCCGGAACCGCATCGC
CTCACGCAGCCTGTCGCCCGGCGCACGCCTTCCCTCGGTTCGGGCCTGCGCGAAAACGCTGCAGGTTTCGAGTTCGACGG
TTGTTGAAGCCTATGAACGGCTGGTGGCCGAAGGCATCATTCGTTCGCGCCCCGGCTCCGGATTCTATGTCACCGCACCG
CTCGCGCCGCTCTCGCTTGCCGAAATCGGACCCAAGCTCGACCGAGAGATCGACCCCCTATGGATATCGCGCCAATCATT
GGCCAGCGGGGAGGACGTGCTGAAACCAGGCTGCGGCTGGCTCCCCGCATCCTGGATGCCGGAGGAAGCATTGCGCAAGG
CGCTGCGCGCGCTTTCCCGCGCCGACACTTCCACCTTGGCGGATTACGGCACGCCGTTCGGCCTGCCTGCGCTGCGTGTG
CTGCTTGCCCGCCGAATGGCGGATCACGGAATAGAAGCTGCGCCAGAGCAGATCATCCTCACCGAGTCGGGAACCCACGC
TATCGACCTTCTCTGCCGTTTTCTCTTAGAGCCCGGTGATGCGGTGATCGTGGACGACCCCTGCTACTTCAATTTTCATG
CTCTCTTGCGGGCGCATCGCGCCAAGCCGGTCGGAGTGCCCTATACGCCGAACGGCCCCGACATTGCTCAGTTCGCCAAA
GCCCTGGAGGAACACCGGCCACGGCTCTACATCACCAATTCCGCTCTGCAGAACCCGACCGGCGTAACGCTTTCACCCGT
GACAGCCCACAAGATCCTGAAGCTTGCGGAAGATAGCGGGCTCACCATCATCGAGGACGATATCTTCGCCGATTTCGAGT
GGAAGCACGCGCCGCGGCTCGCGGCCTTCGACGGCCTGGAACGGGTGGTGCATATCGGGAGCTTCTCCAAGACCCTTTCG
GCCTCGATTCGGTGCGGCTTTATCGCGGCGCCCCGCCGGTGGATCGAAGATCTCGCCGACCTGAAAGTAGCTACCAGTTT
TGGCGGAGGGCGTCTCTCGGCCGAGCTCGTCTTGATGTTGCTCAAAGACGGAACCTACCGCCGACACCTTGAAGCCCTGC
GTACCCGCCTGGCAAGCGCGATGGAGGAAACGATCACACGGCTTAAGCCCCTCGGCATAGAGCCATGGGTAAAACCTGAA
GGTGGCCTTTTTCTCTGGTGCAGGCTTCCGGAAGGAATCGACGCAGCAGCGGTCGCGCGACGTGCCCTCTCCGAAAATGT
CGTGCTGGCACCCGGAAACGCCTTCAGCCTCTCACATTCGGCGAACGGTTTCCTGCGCTTCAATGTCGCTCAGTCAAAGG
ACGAGCGGATCTATCGCGTGCTTGAGATGGCCATGCGCGATTACGGCGGGCTTATGGGGCAAAGACCGAGATCGCCTTGG
GATGCACTTTGA

Upstream 100 bases:

>100_bases
CATCTCCATTTTGCCCCTTGCATCCGAAACGGGCACGAACTTTTCCAGAGACAGGGCGGTACAATTTGCTAAAACTGTTC
TCTCACGGGAGCAGTACAGT

Downstream 100 bases:

>100_bases
AATGCGCTGGCGTGGAGGTCACGATTTCGCCGTCGGCATTGACGGGCATGGGTGCCTCCGTCTCGATATCGAATTCCACG
CATTTCGCCGTCCGCACCTC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MEQRLDRTANGGRLVDMVMDAVRNRIASRSLSPGARLPSVRACAKTLQVSSSTVVEAYERLVAEGIIRSRPGSGFYVTAP
LAPLSLAEIGPKLDREIDPLWISRQSLASGEDVLKPGCGWLPASWMPEEALRKALRALSRADTSTLADYGTPFGLPALRV
LLARRMADHGIEAAPEQIILTESGTHAIDLLCRFLLEPGDAVIVDDPCYFNFHALLRAHRAKPVGVPYTPNGPDIAQFAK
ALEEHRPRLYITNSALQNPTGVTLSPVTAHKILKLAEDSGLTIIEDDIFADFEWKHAPRLAAFDGLERVVHIGSFSKTLS
ASIRCGFIAAPRRWIEDLADLKVATSFGGGRLSAELVLMLLKDGTYRRHLEALRTRLASAMEETITRLKPLGIEPWVKPE
GGLFLWCRLPEGIDAAAVARRALSENVVLAPGNAFSLSHSANGFLRFNVAQSKDERIYRVLEMAMRDYGGLMGQRPRSPW
DAL

Sequences:

>Translated_483_residues
MEQRLDRTANGGRLVDMVMDAVRNRIASRSLSPGARLPSVRACAKTLQVSSSTVVEAYERLVAEGIIRSRPGSGFYVTAP
LAPLSLAEIGPKLDREIDPLWISRQSLASGEDVLKPGCGWLPASWMPEEALRKALRALSRADTSTLADYGTPFGLPALRV
LLARRMADHGIEAAPEQIILTESGTHAIDLLCRFLLEPGDAVIVDDPCYFNFHALLRAHRAKPVGVPYTPNGPDIAQFAK
ALEEHRPRLYITNSALQNPTGVTLSPVTAHKILKLAEDSGLTIIEDDIFADFEWKHAPRLAAFDGLERVVHIGSFSKTLS
ASIRCGFIAAPRRWIEDLADLKVATSFGGGRLSAELVLMLLKDGTYRRHLEALRTRLASAMEETITRLKPLGIEPWVKPE
GGLFLWCRLPEGIDAAAVARRALSENVVLAPGNAFSLSHSANGFLRFNVAQSKDERIYRVLEMAMRDYGGLMGQRPRSPW
DAL
>Mature_483_residues
MEQRLDRTANGGRLVDMVMDAVRNRIASRSLSPGARLPSVRACAKTLQVSSSTVVEAYERLVAEGIIRSRPGSGFYVTAP
LAPLSLAEIGPKLDREIDPLWISRQSLASGEDVLKPGCGWLPASWMPEEALRKALRALSRADTSTLADYGTPFGLPALRV
LLARRMADHGIEAAPEQIILTESGTHAIDLLCRFLLEPGDAVIVDDPCYFNFHALLRAHRAKPVGVPYTPNGPDIAQFAK
ALEEHRPRLYITNSALQNPTGVTLSPVTAHKILKLAEDSGLTIIEDDIFADFEWKHAPRLAAFDGLERVVHIGSFSKTLS
ASIRCGFIAAPRRWIEDLADLKVATSFGGGRLSAELVLMLLKDGTYRRHLEALRTRLASAMEETITRLKPLGIEPWVKPE
GGLFLWCRLPEGIDAAAVARRALSENVVLAPGNAFSLSHSANGFLRFNVAQSKDERIYRVLEMAMRDYGGLMGQRPRSPW
DAL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=373, Percent_Identity=23.5924932975871, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI33469970, Length=373, Percent_Identity=23.5924932975871, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1787710, Length=469, Percent_Identity=30.7036247334755, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1790797, Length=458, Percent_Identity=27.7292576419214, Blast_Score=145, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21356535, Length=394, Percent_Identity=23.3502538071066, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52996; Mature: 52996

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50949 HTH_GNTR ; PS00048 PROTAMINE_P1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRLDRTANGGRLVDMVMDAVRNRIASRSLSPGARLPSVRACAKTLQVSSSTVVEAYER
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
LVAEGIIRSRPGSGFYVTAPLAPLSLAEIGPKLDREIDPLWISRQSLASGEDVLKPGCGW
HHHHHHHHCCCCCCEEEECCCCCHHHHHCCCHHCCCCCCCEEEHHHHCCCCHHHCCCCCC
LPASWMPEEALRKALRALSRADTSTLADYGTPFGLPALRVLLARRMADHGIEAAPEQIIL
CCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
TESGTHAIDLLCRFLLEPGDAVIVDDPCYFNFHALLRAHRAKPVGVPYTPNGPDIAQFAK
ECCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
ALEEHRPRLYITNSALQNPTGVTLSPVTAHKILKLAEDSGLTIIEDDIFADFEWKHAPRL
HHHHCCCEEEEECCCCCCCCCCEECCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCH
AAFDGLERVVHIGSFSKTLSASIRCGFIAAPRRWIEDLADLKVATSFGGGRLSAELVLML
HHHHHHHHHHHHCCHHHHHHHHHEECEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LKDGTYRRHLEALRTRLASAMEETITRLKPLGIEPWVKPEGGLFLWCRLPEGIDAAAVAR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
RALSENVVLAPGNAFSLSHSANGFLRFNVAQSKDERIYRVLEMAMRDYGGLMGQRPRSPW
HHHCCCEEECCCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DAL
CCC
>Mature Secondary Structure
MEQRLDRTANGGRLVDMVMDAVRNRIASRSLSPGARLPSVRACAKTLQVSSSTVVEAYER
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
LVAEGIIRSRPGSGFYVTAPLAPLSLAEIGPKLDREIDPLWISRQSLASGEDVLKPGCGW
HHHHHHHHCCCCCCEEEECCCCCHHHHHCCCHHCCCCCCCEEEHHHHCCCCHHHCCCCCC
LPASWMPEEALRKALRALSRADTSTLADYGTPFGLPALRVLLARRMADHGIEAAPEQIIL
CCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
TESGTHAIDLLCRFLLEPGDAVIVDDPCYFNFHALLRAHRAKPVGVPYTPNGPDIAQFAK
ECCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
ALEEHRPRLYITNSALQNPTGVTLSPVTAHKILKLAEDSGLTIIEDDIFADFEWKHAPRL
HHHHCCCEEEEECCCCCCCCCCEECCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCH
AAFDGLERVVHIGSFSKTLSASIRCGFIAAPRRWIEDLADLKVATSFGGGRLSAELVLML
HHHHHHHHHHHHCCHHHHHHHHHEECEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LKDGTYRRHLEALRTRLASAMEETITRLKPLGIEPWVKPEGGLFLWCRLPEGIDAAAVAR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
RALSENVVLAPGNAFSLSHSANGFLRFNVAQSKDERIYRVLEMAMRDYGGLMGQRPRSPW
HHHCCCEEECCCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DAL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]