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The map label for this gene is dgdR [H]

Identifier: 110632545

GI number: 110632545

Start: 228538

End: 229497

Strand: Reverse

Name: dgdR [H]

Synonym: Meso_0183

Alternate gene names: 110632545

Gene position: 229497-228538 (Counterclockwise)

Preceding gene: 110632547

Following gene: 110632544

Centisome position: 5.2

GC content: 60.42

Gene sequence:

>960_bases
ATGTCGGCGCCGCTCGATCTCGACCAGCTTGCGACCTTTATCGCCATTGCGGACACGGGAAGCTTCACGCGAGCGGCGGA
AGAGGTTCATCGAACACAATCAGCAGTGTCCATGCAGATGCGGCGCCTCGAAGAGCGGGTAGGGAAGCCGCTCTTCGAGA
AAGACGGCCGTTCGAACCGGCTGACCGACGATGGCGAGCGGCTGCTCCTCTACGCCCGGAGGCTCCTGCGCCTCAATCGC
GAAACGCTGGCTGCCTTCGATGACGACAGCCTTGAGGGACATGTGCGGATCGGCATGCCCGATGATTATGCCGAGCGTTT
CCTGCCGGAGATTATGGCCCGCTTCTCCCACTCCAACCCGCGTGTGGAGATGTCGGTTCTTTGCGAGCCGACTGCCAACC
TGGTGCACCACGTCCGGCAAGGCAATGTGGATCTTGCCCTGGTGACGGATCAGGAAGGGGCAGAGACAGTGCGGCGCGAG
CCGCTCTTGTGGGTCGGTTCGGCCAATCACTCCACCCATGAGCGTGAAGTGTTGCCAATGGCTTTTGGACGGCCAACCTG
CAATTGGCGACGGCTTGCCTGCGATACGTTGCGCGAAATCAACCGCGATTATCGAATCCTTTTTACAAGCTTCTCGGCAA
CCGTGATCACCGCTGCGGTTCTGTCTGGAGCGGCGATCTCCGTCCTTCCGGAATGCACACTCAGACCCGGAATGCGGATT
CTCGCGGAAAAGGACGGCTTCCCAAAGCTGCCGGACTGCCATATCGGCATCATGCGAGGACGCACGAACCAGACCGAGCT
CGTGGACGCGCTTGCACGCCACATTTCGGAAAGCCTGGACAACATCTCCATGCCGCTTTCCGTGGTGGAGGAGACGGAAG
GCCTCGATTTTACCGCCTTCTCGCATCGCATGAAACGGGGTAAGCGCTTGCGACCCAGCCACATGCTACCGGGGTGGTGA

Upstream 100 bases:

>100_bases
CCGTCCTACTCAGGAACGGTGCCCTTCTCTCATAAGGGTATTGATTAGTCGAACGAATGTTTTTAATCTTTTCCATCAAT
GTCCTTTATAGGAGGCCGCA

Downstream 100 bases:

>100_bases
GTTTCTGGAGCACAATTGCCGTGACGTCCCGCGATAGCCGGTGGCCGGTGGGAGGTCCGTCGGCGGCTTAGAACGGGTTG
ACGCTGGAAGCGGCAGGCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSAPLDLDQLATFIAIADTGSFTRAAEEVHRTQSAVSMQMRRLEERVGKPLFEKDGRSNRLTDDGERLLLYARRLLRLNR
ETLAAFDDDSLEGHVRIGMPDDYAERFLPEIMARFSHSNPRVEMSVLCEPTANLVHHVRQGNVDLALVTDQEGAETVRRE
PLLWVGSANHSTHEREVLPMAFGRPTCNWRRLACDTLREINRDYRILFTSFSATVITAAVLSGAAISVLPECTLRPGMRI
LAEKDGFPKLPDCHIGIMRGRTNQTELVDALARHISESLDNISMPLSVVEETEGLDFTAFSHRMKRGKRLRPSHMLPGW

Sequences:

>Translated_319_residues
MSAPLDLDQLATFIAIADTGSFTRAAEEVHRTQSAVSMQMRRLEERVGKPLFEKDGRSNRLTDDGERLLLYARRLLRLNR
ETLAAFDDDSLEGHVRIGMPDDYAERFLPEIMARFSHSNPRVEMSVLCEPTANLVHHVRQGNVDLALVTDQEGAETVRRE
PLLWVGSANHSTHEREVLPMAFGRPTCNWRRLACDTLREINRDYRILFTSFSATVITAAVLSGAAISVLPECTLRPGMRI
LAEKDGFPKLPDCHIGIMRGRTNQTELVDALARHISESLDNISMPLSVVEETEGLDFTAFSHRMKRGKRLRPSHMLPGW
>Mature_318_residues
SAPLDLDQLATFIAIADTGSFTRAAEEVHRTQSAVSMQMRRLEERVGKPLFEKDGRSNRLTDDGERLLLYARRLLRLNRE
TLAAFDDDSLEGHVRIGMPDDYAERFLPEIMARFSHSNPRVEMSVLCEPTANLVHHVRQGNVDLALVTDQEGAETVRREP
LLWVGSANHSTHEREVLPMAFGRPTCNWRRLACDTLREINRDYRILFTSFSATVITAAVLSGAAISVLPECTLRPGMRIL
AEKDGFPKLPDCHIGIMRGRTNQTELVDALARHISESLDNISMPLSVVEETEGLDFTAFSHRMKRGKRLRPSHMLPGW

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=280, Percent_Identity=32.8571428571429, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787806, Length=256, Percent_Identity=27.34375, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=39.6551724137931, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790208, Length=150, Percent_Identity=34, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790399, Length=263, Percent_Identity=26.9961977186312, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787601, Length=159, Percent_Identity=26.4150943396226, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788748, Length=146, Percent_Identity=31.5068493150685, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786401, Length=163, Percent_Identity=30.0613496932515, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=146, Percent_Identity=30.1369863013699, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693105, Length=160, Percent_Identity=26.875, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788887, Length=180, Percent_Identity=28.8888888888889, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082132, Length=250, Percent_Identity=26, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=27.843137254902, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI48994962, Length=151, Percent_Identity=29.8013245033113, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87081904, Length=143, Percent_Identity=27.972027972028, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35999; Mature: 35867

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPLDLDQLATFIAIADTGSFTRAAEEVHRTQSAVSMQMRRLEERVGKPLFEKDGRSNR
CCCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC
LTDDGERLLLYARRLLRLNRETLAAFDDDSLEGHVRIGMPDDYAERFLPEIMARFSHSNP
CCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC
RVEMSVLCEPTANLVHHVRQGNVDLALVTDQEGAETVRREPLLWVGSANHSTHEREVLPM
CEEEEEEECCHHHHHHHHHCCCEEEEEEECCCCHHHHHHCCEEEEECCCCCCCCCEECHH
AFGRPTCNWRRLACDTLREINRDYRILFTSFSATVITAAVLSGAAISVLPECTLRPGMRI
HCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEE
LAEKDGFPKLPDCHIGIMRGRTNQTELVDALARHISESLDNISMPLSVVEETEGLDFTAF
EECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHH
SHRMKRGKRLRPSHMLPGW
HHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPLDLDQLATFIAIADTGSFTRAAEEVHRTQSAVSMQMRRLEERVGKPLFEKDGRSNR
CCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC
LTDDGERLLLYARRLLRLNRETLAAFDDDSLEGHVRIGMPDDYAERFLPEIMARFSHSNP
CCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC
RVEMSVLCEPTANLVHHVRQGNVDLALVTDQEGAETVRREPLLWVGSANHSTHEREVLPM
CEEEEEEECCHHHHHHHHHCCCEEEEEEECCCCHHHHHHCCEEEEECCCCCCCCCEECHH
AFGRPTCNWRRLACDTLREINRDYRILFTSFSATVITAAVLSGAAISVLPECTLRPGMRI
HCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEE
LAEKDGFPKLPDCHIGIMRGRTNQTELVDALARHISESLDNISMPLSVVEETEGLDFTAF
EECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHH
SHRMKRGKRLRPSHMLPGW
HHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]