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The map label for this gene is yodT [H]

Identifier: 110632538

GI number: 110632538

Start: 219023

End: 220345

Strand: Direct

Name: yodT [H]

Synonym: Meso_0176

Alternate gene names: 110632538

Gene position: 219023-220345 (Clockwise)

Preceding gene: 110632537

Following gene: 110632539

Centisome position: 4.96

GC content: 61.3

Gene sequence:

>1323_bases
ATGACCTATATCTTGCATCGCCAGATTCATGGCCAATTGCCTGTCGCTGCGGGCGGCCGGGGTGTAAAGCTCTTCGACAG
CGCGGGGAAGGAATATATCGACGCTTCGGGCGGGGCGGCGGTTTCCTGCCTCGGCCACAATCATCCTGATGTGGTGGCTG
CGCTAAAACGCCAGGCCGAGAAACTCGCCTACGCGCACACGAGCTTTTTCACTAACGAGCCAGCCGAGGCGCTGGCCGAG
AGGCTGGTAAAGGCGGCGCCGGAGGGTATCAGCCATGCCTACCTCGTATCAGGGGGGTCGGAGGCGAACGAGGCTGCGCT
GAAGATGGCGCGGCAATTTTTTGTCGAGAAGGGCGAAGCGCAGAGGCGGCACATCATCGCCCGCCGCCAGAGCTACCACG
GCAACACGCTGGGTGCGCTTGCTGCGGGCGGAAACGAGTGGCGCCGGGCCCAATTCCGACCGCTTTTGATTGAAACGCAT
CACATTGACCCTTGCTATGCCTATCGCTACCGGCAGCAAGGGGAAAGCGATGAGGAATACGGTCTGCGCGCTGCTCAGCA
GCTGGAGGACAAGATCCTTGAACTCGGGCCTGATACGGTTATGGCCTTCATCGCCGAGCCGGTGGTGGGCGCCACTGCGG
GCGCGGTGCCGGCCGTATCGGGCTATTTCAAGCGCATTCGCGATATCTGCGACCGCTACGGCGTGCTGCTTATCCTAGAC
GAGGTCATGTGCGGCATGGGCCGTACAGGTACGCTTTTCGCCTGCGAGGAGGACGGTGTTTCGCCCGATCTCGTCTCGAT
CGCCAAGGGTCTCGGTGGCGGCTATCAGCCGGTCGGCGCCGTGCTCCTCTCCCGCCAAATCTTCGATGCCTTTGCGCAGG
GTTCAGGCCTTTTTCAGCACGGCCACACTTATATTTGTCACCCGATGGCCTGTGCTGCCGCTCTTGCGGTGCAGGAGGTG
ATCGAACGCGACAACCTGCTCGCCAATGTGCGGGAGATGGGAAGCTATCTTCGTGCGCGCCTTGAAGCACGATTCGGCAA
TCATGCCCATGTGGGCGATATCCGCGGCCGGGGACTTTTCCTTGGCTTGGAACTGGTCGCCGACCGCGCCACCAAGGAAC
CGTTCGACCCGGCACGCAAGATTCATGCAGGCGTGAAGAAGGAAGCTATGGCGCGGGGCCTTATGGTTTATCCTGCCGGA
GGAACCATAGACGGCGCGCGCGGCGATCACGTGCTTCTTGCCCCGCCATTCATTCTGGACAAAGAGACGGCGGATACCAT
CGTCGATCGCCTGGGAGAGGCAATCGATGCTGCGTTGGGTTAA

Upstream 100 bases:

>100_bases
ACGCGGCTCTAGAGGTGATTGCCCGCACGGAGCGCCAGCTTTCCGACCTCAAGGTTCACGTTTTCGAATACGGGTCCGCG
CATCGGCAAGGAAACCATTC

Downstream 100 bases:

>100_bases
AAAAAGATGCAAAGGGAGGACGCCGGAAGCCCATCCTGAACACTGAGGAATACATAAACAATCTGTTGCAACTTGCGGCA
GAATGCGCAGTTTAGTCATC

Product: hypothetical protein

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTYILHRQIHGQLPVAAGGRGVKLFDSAGKEYIDASGGAAVSCLGHNHPDVVAALKRQAEKLAYAHTSFFTNEPAEALAE
RLVKAAPEGISHAYLVSGGSEANEAALKMARQFFVEKGEAQRRHIIARRQSYHGNTLGALAAGGNEWRRAQFRPLLIETH
HIDPCYAYRYRQQGESDEEYGLRAAQQLEDKILELGPDTVMAFIAEPVVGATAGAVPAVSGYFKRIRDICDRYGVLLILD
EVMCGMGRTGTLFACEEDGVSPDLVSIAKGLGGGYQPVGAVLLSRQIFDAFAQGSGLFQHGHTYICHPMACAAALAVQEV
IERDNLLANVREMGSYLRARLEARFGNHAHVGDIRGRGLFLGLELVADRATKEPFDPARKIHAGVKKEAMARGLMVYPAG
GTIDGARGDHVLLAPPFILDKETADTIVDRLGEAIDAALG

Sequences:

>Translated_440_residues
MTYILHRQIHGQLPVAAGGRGVKLFDSAGKEYIDASGGAAVSCLGHNHPDVVAALKRQAEKLAYAHTSFFTNEPAEALAE
RLVKAAPEGISHAYLVSGGSEANEAALKMARQFFVEKGEAQRRHIIARRQSYHGNTLGALAAGGNEWRRAQFRPLLIETH
HIDPCYAYRYRQQGESDEEYGLRAAQQLEDKILELGPDTVMAFIAEPVVGATAGAVPAVSGYFKRIRDICDRYGVLLILD
EVMCGMGRTGTLFACEEDGVSPDLVSIAKGLGGGYQPVGAVLLSRQIFDAFAQGSGLFQHGHTYICHPMACAAALAVQEV
IERDNLLANVREMGSYLRARLEARFGNHAHVGDIRGRGLFLGLELVADRATKEPFDPARKIHAGVKKEAMARGLMVYPAG
GTIDGARGDHVLLAPPFILDKETADTIVDRLGEAIDAALG
>Mature_439_residues
TYILHRQIHGQLPVAAGGRGVKLFDSAGKEYIDASGGAAVSCLGHNHPDVVAALKRQAEKLAYAHTSFFTNEPAEALAER
LVKAAPEGISHAYLVSGGSEANEAALKMARQFFVEKGEAQRRHIIARRQSYHGNTLGALAAGGNEWRRAQFRPLLIETHH
IDPCYAYRYRQQGESDEEYGLRAAQQLEDKILELGPDTVMAFIAEPVVGATAGAVPAVSGYFKRIRDICDRYGVLLILDE
VMCGMGRTGTLFACEEDGVSPDLVSIAKGLGGGYQPVGAVLLSRQIFDAFAQGSGLFQHGHTYICHPMACAAALAVQEVI
ERDNLLANVREMGSYLRARLEARFGNHAHVGDIRGRGLFLGLELVADRATKEPFDPARKIHAGVKKEAMARGLMVYPAGG
TIDGARGDHVLLAPPFILDKETADTIVDRLGEAIDAALG

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=415, Percent_Identity=30.8433734939759, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI13994255, Length=397, Percent_Identity=30.4785894206549, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=30.8860759493671, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI226442705, Length=415, Percent_Identity=30.1204819277108, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4557809, Length=427, Percent_Identity=30.2107728337237, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI24119277, Length=361, Percent_Identity=28.2548476454294, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI284507298, Length=342, Percent_Identity=28.9473684210526, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1788044, Length=419, Percent_Identity=35.5608591885441, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1789759, Length=427, Percent_Identity=32.0843091334895, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI145693181, Length=415, Percent_Identity=30.1204819277108, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=34.0852130325814, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1786991, Length=430, Percent_Identity=30.9302325581395, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787560, Length=422, Percent_Identity=30.8056872037915, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786349, Length=318, Percent_Identity=30.188679245283, Blast_Score=102, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=451, Percent_Identity=30.820399113082, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI25144271, Length=431, Percent_Identity=28.0742459396752, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=27.8422273781903, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI25144274, Length=250, Percent_Identity=31.6, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=391, Percent_Identity=24.8081841432225, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=430, Percent_Identity=30.6976744186047, Blast_Score=171, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323470, Length=435, Percent_Identity=28.2758620689655, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324386, Length=444, Percent_Identity=25, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321456, Length=376, Percent_Identity=22.8723404255319, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356575, Length=431, Percent_Identity=31.554524361949, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21357415, Length=426, Percent_Identity=30.9859154929577, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI28574759, Length=437, Percent_Identity=29.9771167048055, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI161085790, Length=433, Percent_Identity=29.7921478060046, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI281366494, Length=380, Percent_Identity=23.4210526315789, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667139, Length=380, Percent_Identity=23.4210526315789, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667143, Length=380, Percent_Identity=23.4210526315789, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 47423; Mature: 47291

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYILHRQIHGQLPVAAGGRGVKLFDSAGKEYIDASGGAAVSCLGHNHPDVVAALKRQAE
CCEEEEEHHCCCCCCCCCCCCEEHHHHCCHHHCCCCCCCEEEECCCCCHHHHHHHHHHHH
KLAYAHTSFFTNEPAEALAERLVKAAPEGISHAYLVSGGSEANEAALKMARQFFVEKGEA
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCH
QRRHIIARRQSYHGNTLGALAAGGNEWRRAQFRPLLIETHHIDPCYAYRYRQQGESDEEY
HHHHHHHHHHCCCCCCCEEEECCCCHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCHHH
GLRAAQQLEDKILELGPDTVMAFIAEPVVGATAGAVPAVSGYFKRIRDICDRYGVLLILD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
EVMCGMGRTGTLFACEEDGVSPDLVSIAKGLGGGYQPVGAVLLSRQIFDAFAQGSGLFQH
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHC
GHTYICHPMACAAALAVQEVIERDNLLANVREMGSYLRARLEARFGNHAHVGDIRGRGLF
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LGLELVADRATKEPFDPARKIHAGVKKEAMARGLMVYPAGGTIDGARGDHVLLAPPFILD
EHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCCEEC
KETADTIVDRLGEAIDAALG
CCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYILHRQIHGQLPVAAGGRGVKLFDSAGKEYIDASGGAAVSCLGHNHPDVVAALKRQAE
CEEEEEHHCCCCCCCCCCCCEEHHHHCCHHHCCCCCCCEEEECCCCCHHHHHHHHHHHH
KLAYAHTSFFTNEPAEALAERLVKAAPEGISHAYLVSGGSEANEAALKMARQFFVEKGEA
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCH
QRRHIIARRQSYHGNTLGALAAGGNEWRRAQFRPLLIETHHIDPCYAYRYRQQGESDEEY
HHHHHHHHHHCCCCCCCEEEECCCCHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCHHH
GLRAAQQLEDKILELGPDTVMAFIAEPVVGATAGAVPAVSGYFKRIRDICDRYGVLLILD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
EVMCGMGRTGTLFACEEDGVSPDLVSIAKGLGGGYQPVGAVLLSRQIFDAFAQGSGLFQH
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHC
GHTYICHPMACAAALAVQEVIERDNLLANVREMGSYLRARLEARFGNHAHVGDIRGRGLF
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LGLELVADRATKEPFDPARKIHAGVKKEAMARGLMVYPAGGTIDGARGDHVLLAPPFILD
EHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCCEEC
KETADTIVDRLGEAIDAALG
CCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]