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The map label for this gene is flhF [H]

Identifier: 109947671

GI number: 109947671

Start: 988382

End: 989755

Strand: Reverse

Name: flhF [H]

Synonym: Hac_1139

Alternate gene names: 109947671

Gene position: 989755-988382 (Counterclockwise)

Preceding gene: 109947672

Following gene: 109947670

Centisome position: 63.69

GC content: 37.19

Gene sequence:

>1374_bases
GTGAAATTCTATACCTATAGTGGGGAGACGGCAGCTGAGGCTTTAAAGATCGCTCAAAGCCACCATGGGGTAGATACGCT
AGTGTTTAAAACTCAAGAAATCCGTAAAAAAACGCTCACTTCTTCTGGGCTTTATGAAATCGTTGTGGCGGTTGAAGAAG
AAGAAAACAAACCCCCTAAAGCCCCCCTTATTCCAGAGAGTTTGTATGATGAAGAATTGAGTGAAGAAGATGTGGTGATG
CAGCTTTCAAGCACTGTGGAAGAAATGCGCAAACTCGCCGGAGTTTCATCCAGTCAGCACCATTATACTTTTTCAAAAAA
TAAGACTCTTTTAGAAAAAGATGCCCCATTAGAAGACACGCCCTTAGAGATTAGTAAGCAAGACGCTTTATTGCAAGCCT
TAAAAGATGAAGCCGATTATAAAAAAGAAAAAAAAGAAAAAGAAATTAAACAAGAAGAAGAAATTAAAGATATTAATCTG
CAATTAAGCAAAATTAGAGACAGCCTGAAACTCATTCAAAACATGTTTTGGGATGAGAAAAACCCAAATTCCGTCAATAT
CCCTCAAGAATTTGCCGAAATTTACAAACTAGCCAAACAAAGTGGGATGAAATCCAGCCATTTAGATGAAATCATGCAAT
TAAGTTTGGAATTAATGCCTTTACGCATGAGAGAAAATTCCATCACTATCAAGCGCTATTTTAGAGAAGTGTTGCGTAAA
ATGATCTTGTGCCGCCCTGAAGATTTGAATTTAAGGCAAAAACGCATTTTAATGCTTGTAGGACCCACAGGCGTGGGGAA
AACAACGACTTTAGCCAAACTAGCCGCACGCTATTCTAGAATGCTGACTAAAAAATACAAGGTGGGCATTATCACTTTGG
ATAATTATCGCATCGGGGCTTTGGAGCAATTGAGTTGGTATGCTAATAAAATGAAAATGAGTATAGAAGCGGTGATTGAC
GCTAAAGATTTTGCTAAAGAAATTGAAGCTTTGGAATATTGCGATTTTATTTTGGTGGATACGACAGGGCATTCGCAATA
CGATAAAGAAAAGATTGCTGGGTTGAAAAAATTTATAGATGGGGGTTATAATATTGATGTGTCTTTAGTACTTTCTGTGA
CCACTAAATACGAAGACATGAAAGATATTTATGATTCTTTTGGGGTGTTGGGGATTGATACTTTAATCTTTACTAAATTA
GATGAGAGTAGGGGGTTAGGGAATTTGTTTTCTTTAGTGCATGAGAGTCAAAAGCCTATCAGTTATCTTTCTATTGGGCA
AGAAGTACCTATGGATTTGAAAGTGGCTACTAATGAATATTTAGTGGATTGCATGCTAGATGGTTTTAATAACCCCAATA
AGGAACAAGCATGA

Upstream 100 bases:

>100_bases
GACAAAATGATTTGACTTTACCTCATCCTAAATGGAATGAAAGGGATTCGGTGTTAGTGCCTTTAACTTTGCAACAAATG
CTTTTTAAAAAAGGGGAGTG

Downstream 100 bases:

>100_bases
ACAATCAAGCGAGCCGCTTAGATAATTTTATGAATACTAAAAACCCTAAAAGTTTTTTTAATAACAAAGGGCATACTAAA
TTCATCGCTATCACAAGCGG

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEEENKPPKAPLIPESLYDEELSEEDVVM
QLSSTVEEMRKLAGVSSSQHHYTFSKNKTLLEKDAPLEDTPLEISKQDALLQALKDEADYKKEKKEKEIKQEEEIKDINL
QLSKIRDSLKLIQNMFWDEKNPNSVNIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSITIKRYFREVLRK
MILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLTKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAVID
AKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKKFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKL
DESRGLGNLFSLVHESQKPISYLSIGQEVPMDLKVATNEYLVDCMLDGFNNPNKEQA

Sequences:

>Translated_457_residues
MKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEEENKPPKAPLIPESLYDEELSEEDVVM
QLSSTVEEMRKLAGVSSSQHHYTFSKNKTLLEKDAPLEDTPLEISKQDALLQALKDEADYKKEKKEKEIKQEEEIKDINL
QLSKIRDSLKLIQNMFWDEKNPNSVNIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSITIKRYFREVLRK
MILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLTKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAVID
AKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKKFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKL
DESRGLGNLFSLVHESQKPISYLSIGQEVPMDLKVATNEYLVDCMLDGFNNPNKEQA
>Mature_457_residues
MKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEEENKPPKAPLIPESLYDEELSEEDVVM
QLSSTVEEMRKLAGVSSSQHHYTFSKNKTLLEKDAPLEDTPLEISKQDALLQALKDEADYKKEKKEKEIKQEEEIKDINL
QLSKIRDSLKLIQNMFWDEKNPNSVNIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSITIKRYFREVLRK
MILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLTKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAVID
AKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKKFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKL
DESRGLGNLFSLVHESQKPISYLSIGQEVPMDLKVATNEYLVDCMLDGFNNPNKEQA

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Escherichia coli, GI1789874, Length=200, Percent_Identity=27.5, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325345, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 52238; Mature: 52238

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEEENKPPK
CEEEEECCCHHHHHHHHHHHCCCCHHEEECHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
APLIPESLYDEELSEEDVVMQLSSTVEEMRKLAGVSSSQHHYTFSKNKTLLEKDAPLEDT
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEECCCCCCCCC
PLEISKQDALLQALKDEADYKKEKKEKEIKQEEEIKDINLQLSKIRDSLKLIQNMFWDEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPNSVNIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSITIKRYFREVLRK
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
MILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLTKKYKVGIITLDNYRIGA
HHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCH
LEQLSWYANKMKMSIEAVIDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKKFID
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHC
GGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKLDESRGLGNLFSLVHESQKPI
CCCCEEEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
SYLSIGQEVPMDLKVATNEYLVDCMLDGFNNPNKEQA
HHHHCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEEENKPPK
CEEEEECCCHHHHHHHHHHHCCCCHHEEECHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
APLIPESLYDEELSEEDVVMQLSSTVEEMRKLAGVSSSQHHYTFSKNKTLLEKDAPLEDT
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEECCCCCCCCC
PLEISKQDALLQALKDEADYKKEKKEKEIKQEEEIKDINLQLSKIRDSLKLIQNMFWDEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPNSVNIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSITIKRYFREVLRK
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
MILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLTKKYKVGIITLDNYRIGA
HHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCH
LEQLSWYANKMKMSIEAVIDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKKFID
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHC
GGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKLDESRGLGNLFSLVHESQKPI
CCCCEEEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
SYLSIGQEVPMDLKVATNEYLVDCMLDGFNNPNKEQA
HHHHCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]