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The map label for this gene is hcpE [H]

Identifier: 109947184

GI number: 109947184

Start: 527458

End: 528234

Strand: Direct

Name: hcpE [H]

Synonym: Hac_0600

Alternate gene names: 109947184

Gene position: 527458-528234 (Clockwise)

Preceding gene: 109947183

Following gene: 109947185

Centisome position: 33.94

GC content: 41.31

Gene sequence:

>777_bases
ATGGGGTATGCAAGCAAGTTAGCTTTAAAAATTGGTTTGATAGGTTTATGTTTGTTTGGCACTCTTAATGGTGTGGAGCA
TCTTGGACACAAAGGGAGTTTTGTTTATAGAGGGGAAGTAGCTTACAACAATAAGGATTATGAGCGAGCGGTTTCTCTTT
ATAAAGATGCGATTAAAAATGGCGAGTCGATCGCTTATGTTTTGTTGGGGATCATGTATAAAGATGGTAGGGGTGTGCCT
AGGAACGACAAGAAAGCGGTAGAGTATTTTAAAAAAGCTGTGGCGTTGGATATTCCTAGAGGGTATAACAATTTAGGCGT
GATGTATAAAGAGGGTAGGGGCGTGCCTAAAGATGAAAAGAAAGCGGTGGAGTATTTCCAAATGGCTGCTAATAAGGGTT
ACACGAGTGCTTACATGAATTTAGGGATCATGTATATGGAAGGCAGAGGTGTTCCAAGCAGTTACATGAAAGCCACGGAG
TATTTTAGGCTAGCGATGGCTAAAGGCAGTGCAGAGGCTTATATCCTTTTAGGGGATCTTTATTATAGTGGGAATGAGCA
ATTGGGCATTGAGCAAGACAAAGAAAAAGCCGTTATTTACTATAAAATGGCAGCTGATGTGGGCTCTTCTCAAGCGTATG
AAGGGTTAGCCAAATCTTATGAATATGGTTTGGGCGTGGAAAAGGATAAGAAACAAGCTGAAGAGTTTAGGCAGCGTGCA
TGCGATTATGACTTGGATAAGAATTGCAGGAAAAGAAACGCTTCAAGCCACCACTAA

Upstream 100 bases:

>100_bases
ACGAGAGTGTTTGTGGGTTTAAAAAAGCATACAATTTCTTAAGACTAAGATAATAATTAGTATTATGATTTAGTTTTTAA
CTATACAACAAGGAGTAATG

Downstream 100 bases:

>100_bases
TTCTTCAGACTTGAGTTTTCTTCAAGGATTTTGCTCGTTTCTTAAGCCTATTATTATCCGCTATTAGCTTGCAAAAAGTG
TTTAATGTTTCAATAAGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine-rich protein E [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MGYASKLALKIGLIGLCLFGTLNGVEHLGHKGSFVYRGEVAYNNKDYERAVSLYKDAIKNGESIAYVLLGIMYKDGRGVP
RNDKKAVEYFKKAVALDIPRGYNNLGVMYKEGRGVPKDEKKAVEYFQMAANKGYTSAYMNLGIMYMEGRGVPSSYMKATE
YFRLAMAKGSAEAYILLGDLYYSGNEQLGIEQDKEKAVIYYKMAADVGSSQAYEGLAKSYEYGLGVEKDKKQAEEFRQRA
CDYDLDKNCRKRNASSHH

Sequences:

>Translated_258_residues
MGYASKLALKIGLIGLCLFGTLNGVEHLGHKGSFVYRGEVAYNNKDYERAVSLYKDAIKNGESIAYVLLGIMYKDGRGVP
RNDKKAVEYFKKAVALDIPRGYNNLGVMYKEGRGVPKDEKKAVEYFQMAANKGYTSAYMNLGIMYMEGRGVPSSYMKATE
YFRLAMAKGSAEAYILLGDLYYSGNEQLGIEQDKEKAVIYYKMAADVGSSQAYEGLAKSYEYGLGVEKDKKQAEEFRQRA
CDYDLDKNCRKRNASSHH
>Mature_257_residues
GYASKLALKIGLIGLCLFGTLNGVEHLGHKGSFVYRGEVAYNNKDYERAVSLYKDAIKNGESIAYVLLGIMYKDGRGVPR
NDKKAVEYFKKAVALDIPRGYNNLGVMYKEGRGVPKDEKKAVEYFQMAANKGYTSAYMNLGIMYMEGRGVPSSYMKATEY
FRLAMAKGSAEAYILLGDLYYSGNEQLGIEQDKEKAVIYYKMAADVGSSQAYEGLAKSYEYGLGVEKDKKQAEEFRQRAC
DYDLDKNCRKRNASSHH

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI151301150, Length=191, Percent_Identity=36.1256544502618, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI19923669, Length=197, Percent_Identity=31.9796954314721, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI217330658, Length=195, Percent_Identity=32.8205128205128, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI217330656, Length=195, Percent_Identity=32.8205128205128, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI33620759, Length=227, Percent_Identity=29.5154185022026, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87081769, Length=197, Percent_Identity=31.9796954314721, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17563256, Length=196, Percent_Identity=32.6530612244898, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21355295, Length=231, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 28924; Mature: 28793

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYASKLALKIGLIGLCLFGTLNGVEHLGHKGSFVYRGEVAYNNKDYERAVSLYKDAIKN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHC
GESIAYVLLGIMYKDGRGVPRNDKKAVEYFKKAVALDIPRGYNNLGVMYKEGRGVPKDEK
CCHHEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCCHHH
KAVEYFQMAANKGYTSAYMNLGIMYMEGRGVPSSYMKATEYFRLAMAKGSAEAYILLGDL
HHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEE
YYSGNEQLGIEQDKEKAVIYYKMAADVGSSQAYEGLAKSYEYGLGVEKDKKQAEEFRQRA
EECCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
CDYDLDKNCRKRNASSHH
CCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
GYASKLALKIGLIGLCLFGTLNGVEHLGHKGSFVYRGEVAYNNKDYERAVSLYKDAIKN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHC
GESIAYVLLGIMYKDGRGVPRNDKKAVEYFKKAVALDIPRGYNNLGVMYKEGRGVPKDEK
CCHHEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCCHHH
KAVEYFQMAANKGYTSAYMNLGIMYMEGRGVPSSYMKATEYFRLAMAKGSAEAYILLGDL
HHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEE
YYSGNEQLGIEQDKEKAVIYYKMAADVGSSQAYEGLAKSYEYGLGVEKDKKQAEEFRQRA
EECCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
CDYDLDKNCRKRNASSHH
CCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]