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The map label for this gene is atpD [H]

Identifier: 109947169

GI number: 109947169

Start: 514109

End: 515509

Strand: Direct

Name: atpD [H]

Synonym: Hac_0582

Alternate gene names: 109947169

Gene position: 514109-515509 (Clockwise)

Preceding gene: 109947168

Following gene: 109947170

Centisome position: 33.08

GC content: 43.97

Gene sequence:

>1401_bases
ATGGAAGGTAAAATCATTCAGGTTTTAGGCCCTGTGGTAGATGTGGAGTTTGAATCCTATCTACCGGCGATTTTTGAAGC
GTTGGATATTAACTTTGAAGTTAACGGCGTTCAAAAATCTTTAGTTTTAGAGGTGGCAGCCCATTTGGGTGGTAATCGTG
TGCGAGCGATTGCTATGGATATGACAGAAGGTTTGGTGCGTAACCAAGTGGTGAAAGCTCGCGGCAAGATGATTGAAGTG
CCTGTGGGCGAAGGAGTGTTGGGGCGTATTTTTAATGTTGTGGGCGAGAGCATTGATAATTTAGAGCCTCTTAAGCCGTC
CTTAATTTGGCCCATTCACAGAAAAGCCCCTAGTTTTGAGCAGCAAAGCACTAAAACAGAAATGTTTGAAACCGGTATTA
AAGTCATTGACTTACTTGCACCTTATTCTAAGGGTGGTAAGGTGGGCTTGTTTGGTGGGGCTGGCGTAGGGAAAACGGTG
ATCATTATGGAGCTTATCCACAATGTGGCTTACAAGCATAATGGGTATTCGGTGTTTGCGGGCGTGGGCGAGCGCACTAG
AGAGGGGAATGATTTGTATTTTGAGATGAAAGAAGGGGGCGTTTTAGACAAAGTCGCGCTGTGCTATGGGCAAATGAATG
AGCCACCGGGCGCTAGGAATCGCATTGCATTCACCGGTTTGACGATGGCGGAGTATTTTCGTGATGAAAAGGGATTAGAT
GTGTTGATGTTTATTGATAATATCTTTAGATACGCTCAAAGCGGTGCGGAAATGAGCGCGTTATTAGGTCGTATCCCTTC
AGCGGTGGGGTATCAGCCCACACTAGCTGGGGAAATGGGGAAACTTCAAGAGCGCATCGCTTCCACTAAAAATGGATCTA
TCACTTCCGTTCAAGCGGTGTATGTGCCGGCCGATGATTTGACTGACCCAGCCCCTGCCTCGGTGTTTGCTCATTTAGAT
GCGACGACGGTATTGAATAGAAAGATCGCTGAAAAAGGGATTTATCCAGCGGTTGATCCCTTAGATTCCACTTCAAGGAT
CTTAAGCCCTCAAATGATAGGCGAGAAGCACTATGAAATCGCCACCGGTATCCAACAAGTTTTGCAAAAATATAAGGATT
TGCAAGACATTATTGCGATTTTAGGATTAGATGAATTGAGCGAAGAAGACAAAAAGATCGTTGAAAGAGCCAGAAAAATT
GAGAAATTTTTATCCCAACCGTTTTTTGTGGCTGAAGTTTTTACAGGAAGTCCGGGTAAATATGTGACTCTTCAAGAGAC
TTTAGAGGGCTTTAGAGGGATTTTAGAGGGTAAATACGATCATATCCCTGAAAACGCATTCTACATGGTGGGTAGCATTC
AAGAGGTTTTAGAAAAAGCTAAAAGCATGAAAAATTCCTAA

Upstream 100 bases:

>100_bases
CAATAAAGCCAGACAAGAGGCGATTACGACCGAGCTAGTAGAAATCAATGCTGGCGTAGAAGCCCTAAAATAAAAATTAC
ATTAATCAAGGAGTAAAGCG

Downstream 100 bases:

>100_bases
GGGTTTGTCATGGCTTTATTGAAAATTAGTGTGGTCGTTCCTGAGGGGGAAGTTTATACAGGAGAGGTTAGAAGCGTTGT
GTTGCCAGGAGTTGAAGGGG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMDMTEGLVRNQVVKARGKMIEV
PVGEGVLGRIFNVVGESIDNLEPLKPSLIWPIHRKAPSFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTV
IIMELIHNVAYKHNGYSVFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
VLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAVYVPADDLTDPAPASVFAHLD
ATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEIATGIQQVLQKYKDLQDIIAILGLDELSEEDKKIVERARKI
EKFLSQPFFVAEVFTGSPGKYVTLQETLEGFRGILEGKYDHIPENAFYMVGSIQEVLEKAKSMKNS

Sequences:

>Translated_466_residues
MEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMDMTEGLVRNQVVKARGKMIEV
PVGEGVLGRIFNVVGESIDNLEPLKPSLIWPIHRKAPSFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTV
IIMELIHNVAYKHNGYSVFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
VLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAVYVPADDLTDPAPASVFAHLD
ATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEIATGIQQVLQKYKDLQDIIAILGLDELSEEDKKIVERARKI
EKFLSQPFFVAEVFTGSPGKYVTLQETLEGFRGILEGKYDHIPENAFYMVGSIQEVLEKAKSMKNS
>Mature_466_residues
MEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMDMTEGLVRNQVVKARGKMIEV
PVGEGVLGRIFNVVGESIDNLEPLKPSLIWPIHRKAPSFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTV
IIMELIHNVAYKHNGYSVFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
VLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAVYVPADDLTDPAPASVFAHLD
ATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEIATGIQQVLQKYKDLQDIIAILGLDELSEEDKKIVERARKI
EKFLSQPFFVAEVFTGSPGKYVTLQETLEGFRGILEGKYDHIPENAFYMVGSIQEVLEKAKSMKNS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=467, Percent_Identity=67.4518201284797, Blast_Score=637, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=320, Percent_Identity=29.0625, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI19913426, Length=448, Percent_Identity=25.4464285714286, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI19913428, Length=432, Percent_Identity=24.537037037037, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI50345984, Length=348, Percent_Identity=25.2873563218391, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4757810, Length=348, Percent_Identity=25.2873563218391, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1790170, Length=462, Percent_Identity=66.6666666666667, Blast_Score=625, Evalue=1e-180,
Organism=Escherichia coli, GI1788251, Length=388, Percent_Identity=28.0927835051546, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790172, Length=388, Percent_Identity=25, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25144756, Length=467, Percent_Identity=66.1670235546039, Blast_Score=626, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17565854, Length=320, Percent_Identity=30.625, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17570191, Length=422, Percent_Identity=24.8815165876777, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=348, Percent_Identity=26.7241379310345, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71988063, Length=352, Percent_Identity=25, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988080, Length=352, Percent_Identity=25, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988074, Length=329, Percent_Identity=23.7082066869301, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=463, Percent_Identity=67.3866090712743, Blast_Score=628, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=429, Percent_Identity=27.5058275058275, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319370, Length=401, Percent_Identity=24.4389027431421, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6320016, Length=260, Percent_Identity=25.7692307692308, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24638766, Length=467, Percent_Identity=68.0942184154176, Blast_Score=636, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=471, Percent_Identity=63.4819532908705, Blast_Score=591, Evalue=1e-169,
Organism=Drosophila melanogaster, GI24583992, Length=398, Percent_Identity=27.3869346733668, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24583988, Length=424, Percent_Identity=25.9433962264151, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24583986, Length=424, Percent_Identity=25.9433962264151, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24583984, Length=424, Percent_Identity=25.9433962264151, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI20129479, Length=336, Percent_Identity=28.2738095238095, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI281361666, Length=419, Percent_Identity=25.2983293556086, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646341, Length=419, Percent_Identity=25.2983293556086, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136796, Length=419, Percent_Identity=25.2983293556086, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24658560, Length=428, Percent_Identity=23.1308411214953, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24638768, Length=95, Percent_Identity=55.7894736842105, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 51173; Mature: 51173

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMD
CCCCEEEECCCHHCCCHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCCEEEEEEHH
MTEGLVRNQVVKARGKMIEVPVGEGVLGRIFNVVGESIDNLEPLKPSLIWPIHRKAPSFE
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEECCHHCCCCCCH
QQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVIIMELIHNVAYKHNGYSVFA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEE
GVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCCCCE
VLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAV
EHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEE
YVPADDLTDPAPASVFAHLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEI
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHCCHHHHH
ATGIQQVLQKYKDLQDIIAILGLDELSEEDKKIVERARKIEKFLSQPFFVAEVFTGSPGK
HHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
YVTLQETLEGFRGILEGKYDHIPENAFYMVGSIQEVLEKAKSMKNS
EEEHHHHHHHHHHHHCCCHHCCCCCCEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMD
CCCCEEEECCCHHCCCHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCCEEEEEEHH
MTEGLVRNQVVKARGKMIEVPVGEGVLGRIFNVVGESIDNLEPLKPSLIWPIHRKAPSFE
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEECCHHCCCCCCH
QQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVIIMELIHNVAYKHNGYSVFA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEE
GVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCCCCE
VLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAV
EHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEE
YVPADDLTDPAPASVFAHLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEI
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHCCHHHHH
ATGIQQVLQKYKDLQDIIAILGLDELSEEDKKIVERARKIEKFLSQPFFVAEVFTGSPGK
HHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
YVTLQETLEGFRGILEGKYDHIPENAFYMVGSIQEVLEKAKSMKNS
EEEHHHHHHHHHHHHCCCHHCCCCCCEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA