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The map label for this gene is ttuB [H]

Identifier: 108812516

GI number: 108812516

Start: 2637932

End: 2639299

Strand: Reverse

Name: ttuB [H]

Synonym: YPN_2355

Alternate gene names: 108812516

Gene position: 2639299-2637932 (Counterclockwise)

Preceding gene: 108812517

Following gene: 108812515

Centisome position: 58.2

GC content: 49.2

Gene sequence:

>1368_bases
ATGAGCGATTCACTGTCTACCGCACCGGGCGTTACCCCGCCGGTCAATAAAAACACACCATTAAGTGCGCAGCAGCAGTC
CGTCATTAATAAACTGTTTCGCCGTCTGATCCCGTTCTTATTCTTGTTGTTTGTTTTTGCCTTCCTTGATCGTATCAATA
TAGGTTTTGCGGGTTTGACGATGGGGAAGGATTTAGGGCTAAGTGCCACAACCTTTGGTTTAGCGACTACATTATTCTAC
GTGACATATATCTTATTCGCGATCCCCAGCAATATCATGTTGGGGATCGTGGGTGCCAGGCGTTGGATTGCGACCATTAT
GGTGCTCTGGGGGATCGCTTCTACCGCGACCTTATTTGCCGTCGGCCCCAACAGTTTGTATCTCTTACGAATGATTGTTG
GGATCACCGAAGCCGGTTTTTTACCCGGCATTCTGGTGTATTTAACTTATTGGTTTCCGGCCCACTTTCGAGCCAGAGCC
AATGCGCTGTTTATGGTGGCGATGCCAGTGACTATGGCGCTCGGCTCTCTGGTTTCCGGCTATATTTTGGCGCTTGATGG
TTTTTTGAATATGCGTGGTTGGCAGTGGCTATTTCTGCTGGAAGGCTTTCCATCGGTCTTGCTGGGGGGGGTGGTCTGGT
TCTATCTGGACGATACCCCGCAGAAAGCGCGCTGGTTAACGAAAGAAGATAAACAGTGTCTGCAAGAGATGCTGGAGAGT
GACCGTTTGCAATTGGCGAAACAGGCGGATTATGGTGCCTTACCACAATCCGCGATGTGGCGGGAAATTTTCACCCCCGT
GGTGCTGATGTATACACTGGCTTACTTCTGTTTAACCAATACCCTAAGTGCGGTGAATATTTGGACGCCGCAGATCCTGC
AAAGTTTTAATCAGAGCAGCAGCAATATCACTATCGGTCTGCTGGCCGCTATCCCACAAGTTTGTACCATTGCCGGCATG
ATCTGGTGGAGTAGACGCTCGGATCGGGTTCAGGAACGCAAAATGCACACGGTTTTGCCGTATCTGTTTGCCGCAGCGGG
GTGGGTGCTGGCATCGGCCACACAAAATAGCGTAATCCAGTTGTTAGGGATCATTATGGCCTCGACCGGGTCATTTACGG
CGATGGCGATTTTCTGGACTACACCGGATCAATCCATCAGCCTGAGAGCCAGAGCTGTTGGTATTGCAGTGATAAATGCC
ACTGGAAATATTGGTTCGGCTGTCAGCCCGGTTTTAATTGGTTGGTTGAAAGACCAGACCGGTAACTTTAATTCCGGGCT
GTATTTCGTTGCCGGTTTATTGGTTATCGGGGCTGTTATTTTCTTGATGATTCCAATGAAAAAGGCACCTCCAAAAGCCA
TTTTCTAA

Upstream 100 bases:

>100_bases
ACAGCCGAGGCACTGGCAGCCCGCTTCGGTGTGGGTAATCATCATCCACCGCTTGCACCATCGGGTGGATATTAACCCTG
TCCGTATCGAGGACATTATC

Downstream 100 bases:

>100_bases
TGGGCTAAGGGACCCACGCCGACAAGAATGTCAGCGAGCCGGTCTTTATTTTGATGACGAGGTAAATATGAAGCCAGAAA
ATTTCCGAGCGAATAACCAA

Product: 4-hydroxyphenylacetate permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSATTFGLATTLFY
VTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARA
NALFMVAMPVTMALGSLVSGYILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLES
DRLQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGM
IWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINA
TGNIGSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF

Sequences:

>Translated_455_residues
MSDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSATTFGLATTLFY
VTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARA
NALFMVAMPVTMALGSLVSGYILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLES
DRLQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGM
IWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINA
TGNIGSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF
>Mature_454_residues
SDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSATTFGLATTLFYV
TYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARAN
ALFMVAMPVTMALGSLVSGYILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLESD
RLQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGMI
WWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINAT
GNIGSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=427, Percent_Identity=31.8501170960187, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1789515, Length=440, Percent_Identity=25.4545454545455, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082320, Length=442, Percent_Identity=21.9457013574661, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789152, Length=434, Percent_Identity=21.6589861751152, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI2367379, Length=447, Percent_Identity=23.2662192393736, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322025, Length=419, Percent_Identity=24.3436754176611, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321698, Length=226, Percent_Identity=25.2212389380531, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50007; Mature: 49876

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
MGKDLGLSATTFGLATTLFYVTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
VGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARANALFMVAMPVTMALGSLVSG
ECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
YILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLES
HHHHHHHHHCCCCCEEEEEHHCCHHHHHHHEEEEEECCCCHHHHHCCHHHHHHHHHHHHH
DRLQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSS
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHCCCC
SNITIGLLAAIPQVCTIAGMIWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQ
CCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINATGNIGSAVSPVLIGWLKDQT
HHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCC
GNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
MGKDLGLSATTFGLATTLFYVTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
VGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARANALFMVAMPVTMALGSLVSG
ECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
YILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLES
HHHHHHHHHCCCCCEEEEEHHCCHHHHHHHEEEEEECCCCHHHHHCCHHHHHHHHHHHHH
DRLQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSS
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHCCCC
SNITIGLLAAIPQVCTIAGMIWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQ
CCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINATGNIGSAVSPVLIGWLKDQT
HHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCC
GNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]