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The map label for this gene is dcyD

Identifier: 108812439

GI number: 108812439

Start: 2561103

End: 2562095

Strand: Reverse

Name: dcyD

Synonym: YPN_2278

Alternate gene names: 108812439

Gene position: 2562095-2561103 (Counterclockwise)

Preceding gene: 108812440

Following gene: 108812438

Centisome position: 56.5

GC content: 51.26

Gene sequence:

>993_bases
GTGACGCTTCAACAAAAACTGACGCAATTCCCGCGTCTCGATCTGGTCGGTAATGCGACGCCATTAGAAAAACTGTCTCG
TCTATCTGATTATCTGGGACGTGAAATTTACATTAAACGTGATGATGTCACGCCTGTGGCGCTTGGCGGGAATAAACTGC
GCAAGCTAGAATTCTTAGCCGCAGATGCCTTGAGACAGGGAGCCGATACGCTGGTTACGGCTGGTGCTATTCAATCTAAT
CATGTCCGCCAAACCGCCGCCGTGGCCGCGAAACTGGGGCTGCATTGCGTTGCGCTGTTGGAAAACCCCATTGGTACTGA
GCAGGCAAACTATCTGACCAATGGGAACCGGCTGTTACTGGACCTATTCAATGTTGATGTTGTGATGTGTGAGGCATTGA
ACGATCCAAATCAGCAATTAGCAGAATTGGCTACCCGCGTGGAAGCGCAGGGTTTCCGCCCATATGTGGTACCGATTGGC
GGTTCTAATGCCTTGGGCGCGCTGGGTTATGTGCAGTGCTCACTGGAAATTGCTGCTCAAGCCGCGGGCAATGTTGCGTT
TAGTTCGGTCGTCGTGGCCTCTGGCAGTGCGGGAACACATGCAGGATTGGCGGTTGGTCTACAGCAGTTGTTACCCGATG
CGGAATTAATCGGTGTGACGGTATCACGTAGTGCCGATGAACAGCGGCCTAAAGTGGCACAGATTCAACAAGCGTTGGCG
ACATCATTAGGGATGACGGACCCATTGGCAAAAATCACCTTGTGGGATAGTTATTTTGCCCCGCAATATGGGATGCCAAA
CGAAGAGGGGATAGCGGCTATTAAGCTCTTGGCAAGACTGGAAGGAATATTGTTGGACCCTGTGTATACCGGTAAGGCGA
TGGCGGGCTTACTTGATGGTATTGAACAGCAAAAATTCTGCGACAAAGGGCCAATTTTATTTATCCACACTGGCGGGGCA
CCTGCGCTGTTTGCTTATCATCCGCAGGTGTAG

Upstream 100 bases:

>100_bases
GATATTGGTCACTGACATCACTCATAAAATCAGTGCTTATTAATGTCACATCTGATAAATCTATATAAAAGCCATGATTC
ATCAATTCCTTGGGGGGCAC

Downstream 100 bases:

>100_bases
CCTAAGCTTTCATTATTACTTATTCCATTTTTAACTATATTTATCATTTTATATTTCTTCACTTCATTAATAGCACTGGT
AAAGTGTTGAATATCAAAAA

Product: D-cysteine desulfhydrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTLQQKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTLVTAGAIQSN
HVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIG
GSNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPKVAQIQQALA
TSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGPILFIHTGGA
PALFAYHPQV

Sequences:

>Translated_330_residues
MTLQQKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTLVTAGAIQSN
HVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIG
GSNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPKVAQIQQALA
TSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGPILFIHTGGA
PALFAYHPQV
>Mature_329_residues
TLQQKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTLVTAGAIQSNH
VRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIGG
SNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPKVAQIQQALAT
SLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGPILFIHTGGAP
ALFAYHPQV

Specific function: Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine

COG id: COG2515

COG function: function code E; 1-aminocyclopropane-1-carboxylate deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACC deaminase/D-cysteine desulfhydrase family

Homologues:

Organism=Escherichia coli, GI87082000, Length=326, Percent_Identity=77.3006134969325, Blast_Score=520, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCYD_YERPE (Q8ZF73)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AB0225
- RefSeq:   NP_992906.1
- RefSeq:   YP_002346839.1
- ProteinModelPortal:   Q8ZF73
- SMR:   Q8ZF73
- GeneID:   1174680
- GeneID:   2764100
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO1845
- KEGG:   ypk:y2462
- KEGG:   ypm:YP_1548
- HOGENOM:   HBG689308
- OMA:   PYLVPIG
- ProtClustDB:   PRK03910
- BioCyc:   YPES187410:Y2462-MONOMER
- BioCyc:   YPES214092:YPO1845-MONOMER
- BRENDA:   4.4.1.15
- HAMAP:   MF_01045
- InterPro:   IPR005966
- InterPro:   IPR001926
- TIGRFAMs:   TIGR01275

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.4.1.15

Molecular weight: Translated: 35040; Mature: 34909

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQQKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLA
CCHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEECCCHHHHHHHHH
ADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLL
HHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEE
DLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIGGSNALGALGYVQCSLEIAAQ
EECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHEEEHHHHHHH
AAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPKVAQIQQALA
HCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHH
TSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDG
HHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCHHHHHHHHH
IEQQKFCDKGPILFIHTGGAPALFAYHPQV
HHHHHHCCCCCEEEEECCCCCEEEEECCCC
>Mature Secondary Structure 
TLQQKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLA
CHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEECCCHHHHHHHHH
ADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLL
HHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEE
DLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIGGSNALGALGYVQCSLEIAAQ
EECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHEEEHHHHHHH
AAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPKVAQIQQALA
HCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHH
TSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDG
HHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCHHHHHHHHH
IEQQKFCDKGPILFIHTGGAPALFAYHPQV
HHHHHHCCCCCEEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430