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The map label for this gene is pabC [H]

Identifier: 108812188

GI number: 108812188

Start: 2289252

End: 2290058

Strand: Reverse

Name: pabC [H]

Synonym: YPN_2026

Alternate gene names: 108812188

Gene position: 2290058-2289252 (Counterclockwise)

Preceding gene: 108812189

Following gene: 108812187

Centisome position: 50.5

GC content: 48.82

Gene sequence:

>807_bases
ATGTTTTGGATTAACGGTGTAGAGCAAAATTTGATTTCAGCTTCGGATCGTTCGGTACAATTTGGTGATGGCTGTTTTAC
CACTGCTCGTGTATCCGATGGGCGGGTTGTTTGGCTTGACCAGCATGTGCTGCGTTTGCAACGGGCGACTGAACGTCTAT
TACTGCCCACGGTCAACTGGAAAATATTGACCAAAGAAATGGTAGAGGCAGCAAGTCATACGGAGAGTGGCGTACTGAAA
GTTATTATCAGTCGTGGAAGTGGTGGCCGAGGCTATAGCGGAACGGCATGTCAGCATCCTACCCGAATCATTTCGCTCAG
TGACTATCCTGCCCATTATTCCACCTGGCGGGATCGCGGTATTTCGTTGGCTCTTAGCCCAGTGCCTCTGGCGCGCAACC
CATTATTGGCCGGTATCAAACATCTAAATCGGTTGGAACAAGTATTGATCCGCGCACATCTTGAACAGACAGAGGCCGAC
GAGGCGGTGGTACTTGACACTGCGGGTCAGCTGGTGGAATGCTGTGCGGCTAATTTATTCTGGCGCAAAGGCAACCAGGT
ATGTACTCCAGATCTCAGTCATTCGGGGGTTGATGGCATTATGCGCCAGCGGATTATTGCCTGTTTAGCGGCTCATAATA
TGCCAGTTGAAATTGTGGTGCAGCCGCTGAATGTACTGGCCGATGCCGATGAAGTTATTGTTTGTAACGCATTGATGCCA
GTACTGCCGGTCAATAAAGTGGGTAAATGGGTATACAAATCGAGAGTGTTATTTGACCTATTAAACCTGCATTGCTGCGA
TATATGA

Upstream 100 bases:

>100_bases
TGTATAAGTTAAATACAGAGCAACCAAATACATGGCAACTGAATGTCTGGCGGCTAATTATATGACAAACAAGACACATC
CCATCTAAAGAGAATCTGAA

Downstream 100 bases:

>100_bases
GTGATGATACCTGCGATGCATAGATATAATTAATTGAGGTTATTGACAAAGTGCCCGCGACGGAGAGAACAGGCAGATCG
TAAAGACGCCGTAAATACAT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MFWINGVEQNLISASDRSVQFGDGCFTTARVSDGRVVWLDQHVLRLQRATERLLLPTVNWKILTKEMVEAASHTESGVLK
VIISRGSGGRGYSGTACQHPTRIISLSDYPAHYSTWRDRGISLALSPVPLARNPLLAGIKHLNRLEQVLIRAHLEQTEAD
EAVVLDTAGQLVECCAANLFWRKGNQVCTPDLSHSGVDGIMRQRIIACLAAHNMPVEIVVQPLNVLADADEVIVCNALMP
VLPVNKVGKWVYKSRVLFDLLNLHCCDI

Sequences:

>Translated_268_residues
MFWINGVEQNLISASDRSVQFGDGCFTTARVSDGRVVWLDQHVLRLQRATERLLLPTVNWKILTKEMVEAASHTESGVLK
VIISRGSGGRGYSGTACQHPTRIISLSDYPAHYSTWRDRGISLALSPVPLARNPLLAGIKHLNRLEQVLIRAHLEQTEAD
EAVVLDTAGQLVECCAANLFWRKGNQVCTPDLSHSGVDGIMRQRIIACLAAHNMPVEIVVQPLNVLADADEVIVCNALMP
VLPVNKVGKWVYKSRVLFDLLNLHCCDI
>Mature_268_residues
MFWINGVEQNLISASDRSVQFGDGCFTTARVSDGRVVWLDQHVLRLQRATERLLLPTVNWKILTKEMVEAASHTESGVLK
VIISRGSGGRGYSGTACQHPTRIISLSDYPAHYSTWRDRGISLALSPVPLARNPLLAGIKHLNRLEQVLIRAHLEQTEAD
EAVVLDTAGQLVECCAANLFWRKGNQVCTPDLSHSGVDGIMRQRIIACLAAHNMPVEIVVQPLNVLADADEVIVCNALMP
VLPVNKVGKWVYKSRVLFDLLNLHCCDI

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=265, Percent_Identity=56.6037735849057, Blast_Score=293, Evalue=9e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 29622; Mature: 29622

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWINGVEQNLISASDRSVQFGDGCFTTARVSDGRVVWLDQHVLRLQRATERLLLPTVNW
CEECCCHHHHHHCCCCCCEEECCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCCCH
KILTKEMVEAASHTESGVLKVIISRGSGGRGYSGTACQHPTRIISLSDYPAHYSTWRDRG
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCC
ISLALSPVPLARNPLLAGIKHLNRLEQVLIRAHLEQTEADEAVVLDTAGQLVECCAANLF
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
WRKGNQVCTPDLSHSGVDGIMRQRIIACLAAHNMPVEIVVQPLNVLADADEVIVCNALMP
HHCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCEEEECHHHH
VLPVNKVGKWVYKSRVLFDLLNLHCCDI
HCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFWINGVEQNLISASDRSVQFGDGCFTTARVSDGRVVWLDQHVLRLQRATERLLLPTVNW
CEECCCHHHHHHCCCCCCEEECCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCCCH
KILTKEMVEAASHTESGVLKVIISRGSGGRGYSGTACQHPTRIISLSDYPAHYSTWRDRG
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCC
ISLALSPVPLARNPLLAGIKHLNRLEQVLIRAHLEQTEADEAVVLDTAGQLVECCAANLF
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
WRKGNQVCTPDLSHSGVDGIMRQRIIACLAAHNMPVEIVVQPLNVLADADEVIVCNALMP
HHCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCEEEECHHHH
VLPVNKVGKWVYKSRVLFDLLNLHCCDI
HCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]