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The map label for this gene is ycfH [H]

Identifier: 108812184

GI number: 108812184

Start: 2285464

End: 2286273

Strand: Reverse

Name: ycfH [H]

Synonym: YPN_2022

Alternate gene names: 108812184

Gene position: 2286273-2285464 (Counterclockwise)

Preceding gene: 108812185

Following gene: 108812183

Centisome position: 50.42

GC content: 49.63

Gene sequence:

>810_bases
ATGTTGTTAGTTGATTCTCATTGCCATCTTGATAGCCTTGATTACCAGACATTGCACAGCAGTGTCGATGACGTATTAGC
CAAAGCTAATGCGCGTGATGTGGGCTTTATTTTGGCTGTTGCCACCACCTTGCCGGGTTTCACCGCCATGACGGCATTGA
TTGGTGAGCGTAAGAATGTGGCGTTCTCATGTGGTGTTCATCCGCTCAACTTGGACGGTGGCTATGATTTTCAGCAGTTG
AGAGAGTTAGCTGCTGGCACTCATGTTGTCGCGATGGGGGAAACTGGGCTGGATTACTTTTATCAGCAAGATAACATCCC
GTTACAGCAAGCTTCCTTCCGTGAGCATATTCGTATTGGCCGCGAATTAAATAAGCCGGTTATCGTGCATACCCGCGATG
CGCGGGAAGATACCCTGTCGATTTTACGCGAAGAGCAGGCGCAGGATTGCGGTGGTGTCTTACATTGCTTTACTGAAGAC
AAAGCCACGGCAGCAACGCTTTTGGACCTTGGCTTTTATATCTCTTTCTCAGGGATTGTCACGTTTCGCAACGCCGAACA
ACTGCGTGATGTTGCGCGCTATGTTCCACTCGATAGGCTGTTGGTGGAAACAGATTCACCGTATCTGGCTCCCGTTCCTC
ATCGTGGCAAAGAGAATCAACCTGCCTATGTCCGTGATGTCGCAGAATATATGGCTGTGCTGAAGGGGGTAAGTCTTGAA
TCGCTGGCTGAAGCGACGACAGCAAACTTCTGCCGGTTATTTCATCTAGACCCTTCAACACTCTCCAGTGAGAAGCGCCC
GCTTCCATAA

Upstream 100 bases:

>100_bases
ATCGTGAATTGTTACTCACTGAGCAACTGCTTAGCTGGGAAACAGCACTGTCCACGGGTACTTATTCCACCTTACCTTCG
TTGTAAAAGAGTTTAATATT

Downstream 100 bases:

>100_bases
GAATACTTTTTTTTTAGCTCGTAATTAATCACCGAAAGAAGTAATGTTCTCACCCAATTTATTGGGTGATGGCGGTTATT
ATTGACGTTTCTTTACGTAA

Product: putative metallodependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MLLVDSHCHLDSLDYQTLHSSVDDVLAKANARDVGFILAVATTLPGFTAMTALIGERKNVAFSCGVHPLNLDGGYDFQQL
RELAAGTHVVAMGETGLDYFYQQDNIPLQQASFREHIRIGRELNKPVIVHTRDAREDTLSILREEQAQDCGGVLHCFTED
KATAATLLDLGFYISFSGIVTFRNAEQLRDVARYVPLDRLLVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
SLAEATTANFCRLFHLDPSTLSSEKRPLP

Sequences:

>Translated_269_residues
MLLVDSHCHLDSLDYQTLHSSVDDVLAKANARDVGFILAVATTLPGFTAMTALIGERKNVAFSCGVHPLNLDGGYDFQQL
RELAAGTHVVAMGETGLDYFYQQDNIPLQQASFREHIRIGRELNKPVIVHTRDAREDTLSILREEQAQDCGGVLHCFTED
KATAATLLDLGFYISFSGIVTFRNAEQLRDVARYVPLDRLLVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
SLAEATTANFCRLFHLDPSTLSSEKRPLP
>Mature_269_residues
MLLVDSHCHLDSLDYQTLHSSVDDVLAKANARDVGFILAVATTLPGFTAMTALIGERKNVAFSCGVHPLNLDGGYDFQQL
RELAAGTHVVAMGETGLDYFYQQDNIPLQQASFREHIRIGRELNKPVIVHTRDAREDTLSILREEQAQDCGGVLHCFTED
KATAATLLDLGFYISFSGIVTFRNAEQLRDVARYVPLDRLLVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
SLAEATTANFCRLFHLDPSTLSSEKRPLP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=30.7116104868914, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=30.3370786516854, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=30.03663003663, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=29.9610894941634, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI225903424, Length=221, Percent_Identity=28.5067873303167, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI225903439, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI14042943, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=28.695652173913, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787342, Length=263, Percent_Identity=76.0456273764259, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI48994985, Length=245, Percent_Identity=32.6530612244898, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=28.2945736434109, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559024, Length=287, Percent_Identity=27.1777003484321, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71980746, Length=270, Percent_Identity=27.4074074074074, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17543026, Length=187, Percent_Identity=28.3422459893048, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=300, Percent_Identity=23.6666666666667, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221330018, Length=206, Percent_Identity=31.0679611650485, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586117, Length=206, Percent_Identity=31.0679611650485, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648690, Length=291, Percent_Identity=25.085910652921, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29806; Mature: 29806

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVDSHCHLDSLDYQTLHSSVDDVLAKANARDVGFILAVATTLPGFTAMTALIGERKNV
CEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCE
AFSCGVHPLNLDGGYDFQQLRELAAGTHVVAMGETGLDYFYQQDNIPLQQASFREHIRIG
EEECCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCHHHEECCCCCHHHHHHHHHHHHH
RELNKPVIVHTRDAREDTLSILREEQAQDCGGVLHCFTEDKATAATLLDLGFYISFSGIV
HHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHEEEEEEE
TFRNAEQLRDVARYVPLDRLLVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
EECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH
SLAEATTANFCRLFHLDPSTLSSEKRPLP
HHHHHHHHHHEEEEECCHHHCCCCCCCCC
>Mature Secondary Structure
MLLVDSHCHLDSLDYQTLHSSVDDVLAKANARDVGFILAVATTLPGFTAMTALIGERKNV
CEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCE
AFSCGVHPLNLDGGYDFQQLRELAAGTHVVAMGETGLDYFYQQDNIPLQQASFREHIRIG
EEECCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCHHHEECCCCCHHHHHHHHHHHHH
RELNKPVIVHTRDAREDTLSILREEQAQDCGGVLHCFTEDKATAATLLDLGFYISFSGIV
HHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHEEEEEEE
TFRNAEQLRDVARYVPLDRLLVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
EECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH
SLAEATTANFCRLFHLDPSTLSSEKRPLP
HHHHHHHHHHEEEEECCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]