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The map label for this gene is paaF [C]

Identifier: 108797949

GI number: 108797949

Start: 1084625

End: 1085563

Strand: Direct

Name: paaF [C]

Synonym: Mmcs_0976

Alternate gene names: 108797949

Gene position: 1084625-1085563 (Clockwise)

Preceding gene: 108797948

Following gene: 108797950

Centisome position: 19.01

GC content: 69.44

Gene sequence:

>939_bases
ATGACGCACGCGATCCGGCCCGTCGACTTCGACAACCTCAAGACCATGACCTACGAGGTGACCGGCCGCATCGCCCGGAT
CACCTTCAACCGGCCCGAGAAGGGCAACGCGATCGTCGCCGACACCCCGCTGGAGTTGTCCGCACTCGTCGAACGCGCCG
ACCTCGACCCGAACGTCCACGTGATCCTGGTGTCCGGCCGGGGCGAGGGCTTCTGCGCGGGCTTCGACCTGTCGGCCTAC
GCCGAAGGCTCGTCGTCGGCCGGCGGCGGCAGCCCGTACCGCGACACCGTGCTCTCCGGGAAGACCCAGGCCGTCAACCA
CCTGCCGGATCAGCCGTGGGATCCGATGATCGACTACCAGATGATGAGCCGCTTCGTCCGCGGCTTCTCGAGCCTGCTGC
ACTGCGACAAGCCGACCGTTGTGAAGATCCACGGCTACTGCGTGGCCGGCGGCACCGACATCGCCCTGCACGCCGACCAG
GTGATCGCCGCCGCCGACGCGAAGATCGGCTACCCGCCCACCCGCGTGTGGGGGGTGCCCGCCGCCGGGATGTGGGCCCA
CCGGCTCGGCGACCAGCGCGCGAAACGCCTTCTGCTGACCGGGGATTGCCTGACCGGAAGACAGGCCGCCGAATGGGGGC
TCGCCGTCGAGGCGCCCGAACCCGAAGACCTCGACGAGCGCACCGAACGCCTCGTCGAACGCATCGCCGCGGTGCCGGTC
AACCAGCTCATCATGGTCAAACTCGCGATGAACTCGGCGCTGCTGCAGCAGGGTGTGGCCACCAGTCGGATGGTCAGCAC
GGTGTTCGACGGCATCGCCCGGCACACGCCGGAGGGGCACGCGTTCGTCGCGCAGTCACGCGAACACGGCTTCCGCGAGG
CGGTGCGGCAGCGTGACGAACCGTTCGGCGACCACGGCCGACGAGCCTCCGGGGTGTAG

Upstream 100 bases:

>100_bases
TTGGTGAAGGGGTGACTTCTTCGGCCGAGCAGACACAAAAGTACCCGACACGCCGCGAATTTCGGGACATATGTGTCTGC
TCGCGAGGAAGGGTGACCGC

Downstream 100 bases:

>100_bases
CCATGCGGTTGACGGCGCGGTCGGTGGTGCTGTCGGTCCTGCTCGGTGCGCATCCGGCCTGGGCCACCGCCAGCGAATTG
ATCCGCCTCACCGCCGATTT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTHAIRPVDFDNLKTMTYEVTGRIARITFNRPEKGNAIVADTPLELSALVERADLDPNVHVILVSGRGEGFCAGFDLSAY
AEGSSSAGGGSPYRDTVLSGKTQAVNHLPDQPWDPMIDYQMMSRFVRGFSSLLHCDKPTVVKIHGYCVAGGTDIALHADQ
VIAAADAKIGYPPTRVWGVPAAGMWAHRLGDQRAKRLLLTGDCLTGRQAAEWGLAVEAPEPEDLDERTERLVERIAAVPV
NQLIMVKLAMNSALLQQGVATSRMVSTVFDGIARHTPEGHAFVAQSREHGFREAVRQRDEPFGDHGRRASGV

Sequences:

>Translated_312_residues
MTHAIRPVDFDNLKTMTYEVTGRIARITFNRPEKGNAIVADTPLELSALVERADLDPNVHVILVSGRGEGFCAGFDLSAY
AEGSSSAGGGSPYRDTVLSGKTQAVNHLPDQPWDPMIDYQMMSRFVRGFSSLLHCDKPTVVKIHGYCVAGGTDIALHADQ
VIAAADAKIGYPPTRVWGVPAAGMWAHRLGDQRAKRLLLTGDCLTGRQAAEWGLAVEAPEPEDLDERTERLVERIAAVPV
NQLIMVKLAMNSALLQQGVATSRMVSTVFDGIARHTPEGHAFVAQSREHGFREAVRQRDEPFGDHGRRASGV
>Mature_311_residues
THAIRPVDFDNLKTMTYEVTGRIARITFNRPEKGNAIVADTPLELSALVERADLDPNVHVILVSGRGEGFCAGFDLSAYA
EGSSSAGGGSPYRDTVLSGKTQAVNHLPDQPWDPMIDYQMMSRFVRGFSSLLHCDKPTVVKIHGYCVAGGTDIALHADQV
IAAADAKIGYPPTRVWGVPAAGMWAHRLGDQRAKRLLLTGDCLTGRQAAEWGLAVEAPEPEDLDERTERLVERIAAVPVN
QLIMVKLAMNSALLQQGVATSRMVSTVFDGIARHTPEGHAFVAQSREHGFREAVRQRDEPFGDHGRRASGV

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Escherichia coli, GI221142681, Length=219, Percent_Identity=26.4840182648402, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787660, Length=233, Percent_Identity=27.0386266094421, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 33906; Mature: 33775

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHAIRPVDFDNLKTMTYEVTGRIARITFNRPEKGNAIVADTPLELSALVERADLDPNVH
CCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCEEEECCCHHHHHHHHHHCCCCCEE
VILVSGRGEGFCAGFDLSAYAEGSSSAGGGSPYRDTVLSGKTQAVNHLPDQPWDPMIDYQ
EEEEECCCCCEEECCCCHHCCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCCCCCHH
MMSRFVRGFSSLLHCDKPTVVKIHGYCVAGGTDIALHADQVIAAADAKIGYPPTRVWGVP
HHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEEHHHHHEECCCCCCCCCCCEECCC
AAGMWAHRLGDQRAKRLLLTGDCLTGRQAAEWGLAVEAPEPEDLDERTERLVERIAAVPV
CCHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCEEEECCCCCCHHHHHHHHHHHHHHCCC
NQLIMVKLAMNSALLQQGVATSRMVSTVFDGIARHTPEGHAFVAQSREHGFREAVRQRDE
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCC
PFGDHGRRASGV
CCCCCCCCCCCC
>Mature Secondary Structure 
THAIRPVDFDNLKTMTYEVTGRIARITFNRPEKGNAIVADTPLELSALVERADLDPNVH
CCCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCEEEECCCHHHHHHHHHHCCCCCEE
VILVSGRGEGFCAGFDLSAYAEGSSSAGGGSPYRDTVLSGKTQAVNHLPDQPWDPMIDYQ
EEEEECCCCCEEECCCCHHCCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCCCCCHH
MMSRFVRGFSSLLHCDKPTVVKIHGYCVAGGTDIALHADQVIAAADAKIGYPPTRVWGVP
HHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEEHHHHHEECCCCCCCCCCCEECCC
AAGMWAHRLGDQRAKRLLLTGDCLTGRQAAEWGLAVEAPEPEDLDERTERLVERIAAVPV
CCHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCEEEECCCCCCHHHHHHHHHHHHHHCCC
NQLIMVKLAMNSALLQQGVATSRMVSTVFDGIARHTPEGHAFVAQSREHGFREAVRQRDE
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCC
PFGDHGRRASGV
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA