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The map label for this gene is dfrA [H]

Identifier: 108797852

GI number: 108797852

Start: 971670

End: 972659

Strand: Reverse

Name: dfrA [H]

Synonym: Mmcs_0877

Alternate gene names: 108797852

Gene position: 972659-971670 (Counterclockwise)

Preceding gene: 108797853

Following gene: 108797851

Centisome position: 17.05

GC content: 70.2

Gene sequence:

>990_bases
ATGAGAGTTCTGGTCACAGGGGGCACCGGTTTCGTCGGCGCCTGGACCGCCAAGGCCGTGCAGGATGCCGGCCACCAGGT
CCGCTTCCTGGTCCGCAAACCCGAACGCCTGACCACCAGTGCGGCGAAGATCGGCGCCGACACCGGCGACCACGTCGTCG
GCGACATCTCCGATCCGGACTCGACCGCTGCGGCACTCGACGGTTGCGACGCCGTGATCCATTGCGCGGCAATGGTATCC
ACCGATCCGTCGATGGCCGACGAGATGCTGCGGACCAACCTCGAGGGTGCGCGGTACGTACTCGGCGGCGCGGCGAAGGC
CGGGCTGGATCCGATCATCCACGTCTCGAGCTTCACGGCGCTGTTCCGCCCCGGGCTCGACGTGCTGCACGCCGACCTGC
CGGTCACCGGCGGATCGGACGGCTACGGCAAGTCCAAGGCCGTCGTCGAGGCGTACGCCCGGGGACTGCAGGACGCCGGG
GCGCCGGTCGACATCACGTATCCGGGCATGGTGCTGGGCCCGCCGGCCGGTGACCAGTTCGGCGAGGCCGCCGAAGGTGT
GGAGGCCTCGATCAAGATGCGCAGCGTGCCGGGCCGCGGGGCGGGGTGGATCGTGGTCGACGTCCGCGATCTGGCCGCGC
TGCACGTCGCGCTGCTGGAGCCCGGCCGCGGTCCGCGCCGGTACATGCTGGGCGGCCGCCGGGTGCCCGTGGGCGAACTG
GCGACTCTCATCGGTGACGCCGCCGGACGCGATCTGGCGCCGATCCCCATCCCCGACGTCGCCCTGCGCACGGTCGGCCG
GATTTTCGACGTCATCGGTGACCAACTGCCGTTCGAGACGCCGATCAACTCCGCGGCGATGCAGTACTACACGCAGATGC
CGAAATCCGACGACGCCCCCGCCGAGCGTGATCTCGGCATCAAGCAGCGCGAGGTCGCCGAGACCATCGCCGACACGGTC
GCGGGATTGCGCGAAGTCGGTCGCCTGTAG

Upstream 100 bases:

>100_bases
CCCACTGGTCAACCAAGGCTGACGCGCCCCAGGTTTCACCGGACACTACGAGGGGTACTGTCCGGTGCCATCCTTCCGCA
ACGTCGCAACCGGGGGTCCG

Downstream 100 bases:

>100_bases
CTCCCGACGAGATCCCCGGCGAGGCGTCGTTTACGTTCCCATGCCGGCTTTCGACACCAGGGCTGTGAATTGCGCTCTGG
GTGCGTGACCCCACAGCCAT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRVLVTGGTGFVGAWTAKAVQDAGHQVRFLVRKPERLTTSAAKIGADTGDHVVGDISDPDSTAAALDGCDAVIHCAAMVS
TDPSMADEMLRTNLEGARYVLGGAAKAGLDPIIHVSSFTALFRPGLDVLHADLPVTGGSDGYGKSKAVVEAYARGLQDAG
APVDITYPGMVLGPPAGDQFGEAAEGVEASIKMRSVPGRGAGWIVVDVRDLAALHVALLEPGRGPRRYMLGGRRVPVGEL
ATLIGDAAGRDLAPIPIPDVALRTVGRIFDVIGDQLPFETPINSAAMQYYTQMPKSDDAPAERDLGIKQREVAETIADTV
AGLREVGRL

Sequences:

>Translated_329_residues
MRVLVTGGTGFVGAWTAKAVQDAGHQVRFLVRKPERLTTSAAKIGADTGDHVVGDISDPDSTAAALDGCDAVIHCAAMVS
TDPSMADEMLRTNLEGARYVLGGAAKAGLDPIIHVSSFTALFRPGLDVLHADLPVTGGSDGYGKSKAVVEAYARGLQDAG
APVDITYPGMVLGPPAGDQFGEAAEGVEASIKMRSVPGRGAGWIVVDVRDLAALHVALLEPGRGPRRYMLGGRRVPVGEL
ATLIGDAAGRDLAPIPIPDVALRTVGRIFDVIGDQLPFETPINSAAMQYYTQMPKSDDAPAERDLGIKQREVAETIADTV
AGLREVGRL
>Mature_329_residues
MRVLVTGGTGFVGAWTAKAVQDAGHQVRFLVRKPERLTTSAAKIGADTGDHVVGDISDPDSTAAALDGCDAVIHCAAMVS
TDPSMADEMLRTNLEGARYVLGGAAKAGLDPIIHVSSFTALFRPGLDVLHADLPVTGGSDGYGKSKAVVEAYARGLQDAG
APVDITYPGMVLGPPAGDQFGEAAEGVEASIKMRSVPGRGAGWIVVDVRDLAALHVALLEPGRGPRRYMLGGRRVPVGEL
ATLIGDAAGRDLAPIPIPDVALRTVGRIFDVIGDQLPFETPINSAAMQYYTQMPKSDDAPAERDLGIKQREVAETIADTV
AGLREVGRL

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 34312; Mature: 34312

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVTGGTGFVGAWTAKAVQDAGHQVRFLVRKPERLTTSAAKIGADTGDHVVGDISDPD
CEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEECCCCCC
STAAALDGCDAVIHCAAMVSTDPSMADEMLRTNLEGARYVLGGAAKAGLDPIIHVSSFTA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCHHHCCCCEEEHHHHHH
LFRPGLDVLHADLPVTGGSDGYGKSKAVVEAYARGLQDAGAPVDITYPGMVLGPPAGDQF
HHHCCHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCHH
GEAAEGVEASIKMRSVPGRGAGWIVVDVRDLAALHVALLEPGRGPRRYMLGGRRVPVGEL
HHHHCCCHHEEEEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHH
ATLIGDAAGRDLAPIPIPDVALRTVGRIFDVIGDQLPFETPINSAAMQYYTQMPKSDDAP
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCC
AERDLGIKQREVAETIADTVAGLREVGRL
CHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVLVTGGTGFVGAWTAKAVQDAGHQVRFLVRKPERLTTSAAKIGADTGDHVVGDISDPD
CEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEECCCCCC
STAAALDGCDAVIHCAAMVSTDPSMADEMLRTNLEGARYVLGGAAKAGLDPIIHVSSFTA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCHHHCCCCEEEHHHHHH
LFRPGLDVLHADLPVTGGSDGYGKSKAVVEAYARGLQDAGAPVDITYPGMVLGPPAGDQF
HHHCCHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCHH
GEAAEGVEASIKMRSVPGRGAGWIVVDVRDLAALHVALLEPGRGPRRYMLGGRRVPVGEL
HHHHCCCHHEEEEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHH
ATLIGDAAGRDLAPIPIPDVALRTVGRIFDVIGDQLPFETPINSAAMQYYTQMPKSDDAP
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCC
AERDLGIKQREVAETIADTVAGLREVGRL
CHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]