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The map label for this gene is yvtA [H]

Identifier: 108797825

GI number: 108797825

Start: 938531

End: 939958

Strand: Reverse

Name: yvtA [H]

Synonym: Mmcs_0850

Alternate gene names: 108797825

Gene position: 939958-938531 (Counterclockwise)

Preceding gene: 108797826

Following gene: 108797820

Centisome position: 16.47

GC content: 69.33

Gene sequence:

>1428_bases
GTGACCGAGCGAAACCAGCCCGCCGAAGGCCGGTCGACACCGCCTGCCGGCGACTCCCCGGCGGTCGATCCGGCGACGCA
GCGCGCCTTCGGCCGCCCGGACGGCATCGAGGGGGCGTTCGCCTCCCCCGACCGCCGCCGTGACCAGGGCGAATACACGC
CGACCAACCAGCCCCCCGGGCCTCTGCTCGACAACGTCTTCGGTCAACCCGATCGCGGTGACGAACCGGTGTCGGAGCCC
TGGCCGCCGCAGGCCGAAGACGAGGCCCCGCCTCCTGCGCCCGCGGCTGCGGCGCCCGCGCCCGCCCCGGCCGGCCCCAA
ACTTGGGCTGGTCGACGTGTTGTTCAGCGGGAAGGTGTCGCGTCCGGCGCTCGCCCTGCTCGGTGTGCTGGCGCTCGCGG
TGGGCCTGGCCGGCGGGTGGATGGGCAGCAAGACGGCGTCGATCATCGAGGCGTTCTCGATTCCGAAGGTCAACGTGTCG
AGCACCGCGCGCGACGACGAGGCCGAAGGTCGGTTCACTAAGGTGGCCCGCGCGGTCGCCGACTCGGTGGTCACGATCGA
GGCGATCAGCGAGCAGGCCGGCTCGCAGGGCTCCGGGGTGGTGGTCGACGGCCGCGGTTACATCGTCACCAACAACCACG
TCGTCGAAGAGGCCGCCAGCGATGCGAAGAAGTGGAAGCTGTCGGTGATCTTCAACGACGGCAAGACGGTGCCCGCGCAT
GTCGTCGGCCGCGATCCGGTGACGGATCTGGCGGTGCTGAAGGTCAACAATGTCGACCACCTGACCGTGGCGCGGCTGGG
CGATTCGAATCGCCTGCGCGTCGGGCAGGAGGTGATCGCCGCGGGTGCGCCGCTGGGGCTGCGCAGCACCGACACCGTGG
GCATCATCAGCGCGCTCAACCGCGCGGTGCGCCTGTCGGCGGAGCGTTCGGGTGAGGACATCGTGATCTCGGCGGTGCAG
ACCGATGCGGCGATCAATCACGGCAACTCCGGCGGCCCGTTGATCAACATGAACGCCGAGGTGATCGGTATCAACGCGGC
GGGCAAGTCGCTGTCGGACAGCGCCAGCGGTCTGGGCTTCGCGATCCCGGTCAACGAGATGAAACACGTCGTCGAGACGC
TGATGCGAGACGGCGTGATCGCCCATCCCACACTGGGTTTGACGGCGCAGTCGGTCAGCGATACCGCGGCGGCCGGGGCG
AAGGTGACCGAGGTCAAGCAGGGCGAGCCGGCGGAGAAGGCCGGGATCAAGGACGGCGACGTCGTCGTCAAGATCGGTGA
CCGTCAGATCGGTGACCTCGACTCGTTCGTCGTCGCGGTGCGCCAACTCGAGATCGGTGAGGGCACGCCGGTCGAGATCC
TGCGTGAAGGCAAGCCGATGACGCTGACCGTGGAGCCGGTCGCGGGCAAGCCGACGACCAAGCCGTAA

Upstream 100 bases:

>100_bases
GTGTGCCGCCATCGTAGATCCCGCGCGTGCGCCGAAGCGCCGCGGCGGTGACGGGCATGATGGAGGGTGAGCACGCCGGG
ACGTCGACAGAGGGAGGCGC

Downstream 100 bases:

>100_bases
GAACCAGTCGCCGAGACTGCTCGGAGATCACGCTTTCGCGCGAATCGGCGATCCCCCAGCAGTTTCGGCGTAGCCGAGGC
TTCGCAGGCACTCCTCGACC

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTERNQPAEGRSTPPAGDSPAVDPATQRAFGRPDGIEGAFASPDRRRDQGEYTPTNQPPGPLLDNVFGQPDRGDEPVSEP
WPPQAEDEAPPPAPAAAAPAPAPAGPKLGLVDVLFSGKVSRPALALLGVLALAVGLAGGWMGSKTASIIEAFSIPKVNVS
STARDDEAEGRFTKVARAVADSVVTIEAISEQAGSQGSGVVVDGRGYIVTNNHVVEEAASDAKKWKLSVIFNDGKTVPAH
VVGRDPVTDLAVLKVNNVDHLTVARLGDSNRLRVGQEVIAAGAPLGLRSTDTVGIISALNRAVRLSAERSGEDIVISAVQ
TDAAINHGNSGGPLINMNAEVIGINAAGKSLSDSASGLGFAIPVNEMKHVVETLMRDGVIAHPTLGLTAQSVSDTAAAGA
KVTEVKQGEPAEKAGIKDGDVVVKIGDRQIGDLDSFVVAVRQLEIGEGTPVEILREGKPMTLTVEPVAGKPTTKP

Sequences:

>Translated_475_residues
MTERNQPAEGRSTPPAGDSPAVDPATQRAFGRPDGIEGAFASPDRRRDQGEYTPTNQPPGPLLDNVFGQPDRGDEPVSEP
WPPQAEDEAPPPAPAAAAPAPAPAGPKLGLVDVLFSGKVSRPALALLGVLALAVGLAGGWMGSKTASIIEAFSIPKVNVS
STARDDEAEGRFTKVARAVADSVVTIEAISEQAGSQGSGVVVDGRGYIVTNNHVVEEAASDAKKWKLSVIFNDGKTVPAH
VVGRDPVTDLAVLKVNNVDHLTVARLGDSNRLRVGQEVIAAGAPLGLRSTDTVGIISALNRAVRLSAERSGEDIVISAVQ
TDAAINHGNSGGPLINMNAEVIGINAAGKSLSDSASGLGFAIPVNEMKHVVETLMRDGVIAHPTLGLTAQSVSDTAAAGA
KVTEVKQGEPAEKAGIKDGDVVVKIGDRQIGDLDSFVVAVRQLEIGEGTPVEILREGKPMTLTVEPVAGKPTTKP
>Mature_474_residues
TERNQPAEGRSTPPAGDSPAVDPATQRAFGRPDGIEGAFASPDRRRDQGEYTPTNQPPGPLLDNVFGQPDRGDEPVSEPW
PPQAEDEAPPPAPAAAAPAPAPAGPKLGLVDVLFSGKVSRPALALLGVLALAVGLAGGWMGSKTASIIEAFSIPKVNVSS
TARDDEAEGRFTKVARAVADSVVTIEAISEQAGSQGSGVVVDGRGYIVTNNHVVEEAASDAKKWKLSVIFNDGKTVPAHV
VGRDPVTDLAVLKVNNVDHLTVARLGDSNRLRVGQEVIAAGAPLGLRSTDTVGIISALNRAVRLSAERSGEDIVISAVQT
DAAINHGNSGGPLINMNAEVIGINAAGKSLSDSASGLGFAIPVNEMKHVVETLMRDGVIAHPTLGLTAQSVSDTAAAGAK
VTEVKQGEPAEKAGIKDGDVVVKIGDRQIGDLDSFVVAVRQLEIGEGTPVEILREGKPMTLTVEPVAGKPTTKP

Specific function: May be involved in processing, maturation, or secretion of extracellular enzymes [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=255, Percent_Identity=32.9411764705882, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4506141, Length=282, Percent_Identity=32.9787234042553, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI24308541, Length=289, Percent_Identity=32.1799307958478, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI7019477, Length=298, Percent_Identity=32.8859060402685, Blast_Score=116, Evalue=5e-26,
Organism=Escherichia coli, GI1786356, Length=278, Percent_Identity=38.1294964028777, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1789629, Length=279, Percent_Identity=36.9175627240143, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789630, Length=319, Percent_Identity=32.6018808777429, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24646839, Length=364, Percent_Identity=32.1428571428571, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 48938; Mature: 48806

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERNQPAEGRSTPPAGDSPAVDPATQRAFGRPDGIEGAFASPDRRRDQGEYTPTNQPPG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PLLDNVFGQPDRGDEPVSEPWPPQAEDEAPPPAPAAAAPAPAPAGPKLGLVDVLFSGKVS
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHCCCCC
RPALALLGVLALAVGLAGGWMGSKTASIIEAFSIPKVNVSSTARDDEAEGRFTKVARAVA
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
DSVVTIEAISEQAGSQGSGVVVDGRGYIVTNNHVVEEAASDAKKWKLSVIFNDGKTVPAH
HHHEEEEHHHHHCCCCCCCEEECCCEEEEECCHHHHHHHCCHHEEEEEEEEECCCCCCEE
VVGRDPVTDLAVLKVNNVDHLTVARLGDSNRLRVGQEVIAAGAPLGLRSTDTVGIISALN
EECCCCCCCEEEEEECCCCEEEEEEECCCCCEEHHHHHHHCCCCCCCCCCCHHHHHHHHH
RAVRLSAERSGEDIVISAVQTDAAINHGNSGGPLINMNAEVIGINAAGKSLSDSASGLGF
HHHEEHHCCCCCEEEEEEEECCHHHCCCCCCCCEEECCCEEEEEECCCCCCCCCCCCCEE
AIPVNEMKHVVETLMRDGVIAHPTLGLTAQSVSDTAAAGAKVTEVKQGEPAEKAGIKDGD
EECHHHHHHHHHHHHHCCEEECCCCCCCHHHCCHHHHCCCEEEECCCCCCHHHCCCCCCC
VVVKIGDRQIGDLDSFVVAVRQLEIGEGTPVEILREGKPMTLTVEPVAGKPTTKP
EEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TERNQPAEGRSTPPAGDSPAVDPATQRAFGRPDGIEGAFASPDRRRDQGEYTPTNQPPG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PLLDNVFGQPDRGDEPVSEPWPPQAEDEAPPPAPAAAAPAPAPAGPKLGLVDVLFSGKVS
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHCCCCC
RPALALLGVLALAVGLAGGWMGSKTASIIEAFSIPKVNVSSTARDDEAEGRFTKVARAVA
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
DSVVTIEAISEQAGSQGSGVVVDGRGYIVTNNHVVEEAASDAKKWKLSVIFNDGKTVPAH
HHHEEEEHHHHHCCCCCCCEEECCCEEEEECCHHHHHHHCCHHEEEEEEEEECCCCCCEE
VVGRDPVTDLAVLKVNNVDHLTVARLGDSNRLRVGQEVIAAGAPLGLRSTDTVGIISALN
EECCCCCCCEEEEEECCCCEEEEEEECCCCCEEHHHHHHHCCCCCCCCCCCHHHHHHHHH
RAVRLSAERSGEDIVISAVQTDAAINHGNSGGPLINMNAEVIGINAAGKSLSDSASGLGF
HHHEEHHCCCCCEEEEEEEECCHHHCCCCCCCCEEECCCEEEEEECCCCCCCCCCCCCEE
AIPVNEMKHVVETLMRDGVIAHPTLGLTAQSVSDTAAAGAKVTEVKQGEPAEKAGIKDGD
EECHHHHHHHHHHHHHCCEEECCCCCCCHHHCCHHHHCCCEEEECCCCCCHHHCCCCCCC
VVVKIGDRQIGDLDSFVVAVRQLEIGEGTPVEILREGKPMTLTVEPVAGKPTTKP
EEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10692364; 9353931; 9384377; 10568751; 11133960 [H]