The gene/protein map for NC_008146 is currently unavailable.
Definition Mycobacterium sp. MCS chromosome, complete genome.
Accession NC_008146
Length 5,705,448

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The map label for this gene is acr1 [H]

Identifier: 108797711

GI number: 108797711

Start: 778801

End: 779676

Strand: Reverse

Name: acr1 [H]

Synonym: Mmcs_0732

Alternate gene names: 108797711

Gene position: 779676-778801 (Counterclockwise)

Preceding gene: 108797714

Following gene: 108797710

Centisome position: 13.67

GC content: 70.78

Gene sequence:

>876_bases
GTGAGCAAGAATCCGTTGCGTCGGCTGTCGGACAGCCTGATGCTGACGAGCATGCGGCCGTCGATGGCCGAACAGTTCCT
GCAACCGCGCGCGGACGTCGACCTCACCGGTAAGCGCATCCTGCTGACCGGCGCCTCGTCGGGTATCGGCGAGGCCGCCG
CGGAGAAGTTCGCCCGGCGCGGCGCCACGGTCGTCGCGGTGGCCCGCCGCCAGGATCTGCTCGACGCACTGGTCGGCCGG
ATCTCCGAGGCCGGTGGCGTCGCCGCGGCCCGGGCGTGCGACCTGTCCGACCTCGACGCCGTCGACGAGCTGGTGGCCGA
CGTGGAGGAGCGGTTCGGCGGCGTCGACATCCTGATCAACAACGCGGGCAAGTCAATTCGCCGTCCGCTGGCCGAATCGC
TGGACCGCTGGCACGACGTCGAGCGGACGATGACGCTGAACTACTACTCGCCGCTGCGGCTGATCCGCGGGCTGGCGCCG
GGCATGATCGCCCGCGGCGAGGGCCACATCATCAACGTCGCGACGTGGGGCGTGTTCAGCGAGGCCTCCCCGCTGTTCGG
GGTCTACGTCGCCTCGAAGGCGGCGCTGTCGGCGGTGAGCCGGGTCATCGAGACCGAATGGGCCGACAAGAGCGTGCACT
CCTCAACGCTCTACTACCCGCTGGTGAAGACGCCGATGATCGCGCCCACGAGGGAGTACGACCGGGTGCCGGGGCTGAGC
CCGCAGGAAGCCGCCGACTGGATGATCGCCGCGGCGCGCCACCGGCCGGTGCGGATCGCGCCCCGGATGGCCGTCACCGC
GCGGGCCGTCGACTCGCTGGCGCCGACGTGGTTCAACGCCATCGTCAAGCGGCAGCAGTTCCAGCCGGGGGCCTGA

Upstream 100 bases:

>100_bases
GGTGGCATCACCGGTGACGGCGTCGCCCCGGAGCAGTACCTCGACAGCGTCGGCCAGCGCCATGCATCAGCACTATAGGC
GGCGCGCCTAGACTCCCGGC

Downstream 100 bases:

>100_bases
CCGCCGTGATAGACACAAGCCATGGAGATCCTGGCCAGCCGGATGCTGCTGCGGCCGGCGGACTATCAACGGTCGCTGCG
GTTCTACCGCGACGGGCTCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSKNPLRRLSDSLMLTSMRPSMAEQFLQPRADVDLTGKRILLTGASSGIGEAAAEKFARRGATVVAVARRQDLLDALVGR
ISEAGGVAAARACDLSDLDAVDELVADVEERFGGVDILINNAGKSIRRPLAESLDRWHDVERTMTLNYYSPLRLIRGLAP
GMIARGEGHIINVATWGVFSEASPLFGVYVASKAALSAVSRVIETEWADKSVHSSTLYYPLVKTPMIAPTREYDRVPGLS
PQEAADWMIAAARHRPVRIAPRMAVTARAVDSLAPTWFNAIVKRQQFQPGA

Sequences:

>Translated_291_residues
MSKNPLRRLSDSLMLTSMRPSMAEQFLQPRADVDLTGKRILLTGASSGIGEAAAEKFARRGATVVAVARRQDLLDALVGR
ISEAGGVAAARACDLSDLDAVDELVADVEERFGGVDILINNAGKSIRRPLAESLDRWHDVERTMTLNYYSPLRLIRGLAP
GMIARGEGHIINVATWGVFSEASPLFGVYVASKAALSAVSRVIETEWADKSVHSSTLYYPLVKTPMIAPTREYDRVPGLS
PQEAADWMIAAARHRPVRIAPRMAVTARAVDSLAPTWFNAIVKRQQFQPGA
>Mature_290_residues
SKNPLRRLSDSLMLTSMRPSMAEQFLQPRADVDLTGKRILLTGASSGIGEAAAEKFARRGATVVAVARRQDLLDALVGRI
SEAGGVAAARACDLSDLDAVDELVADVEERFGGVDILINNAGKSIRRPLAESLDRWHDVERTMTLNYYSPLRLIRGLAPG
MIARGEGHIINVATWGVFSEASPLFGVYVASKAALSAVSRVIETEWADKSVHSSTLYYPLVKTPMIAPTREYDRVPGLSP
QEAADWMIAAARHRPVRIAPRMAVTARAVDSLAPTWFNAIVKRQQFQPGA

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=266, Percent_Identity=30.8270676691729, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=191, Percent_Identity=29.8429319371728, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI7706318, Length=206, Percent_Identity=33.0097087378641, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=31.7204301075269, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=31.25, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=30.6878306878307, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705925, Length=193, Percent_Identity=32.1243523316062, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI32455239, Length=182, Percent_Identity=31.8681318681319, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI5031765, Length=182, Percent_Identity=31.8681318681319, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI157739938, Length=274, Percent_Identity=27.007299270073, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI40807363, Length=256, Percent_Identity=26.953125, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI226371731, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705855, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4557649, Length=187, Percent_Identity=26.7379679144385, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4503817, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI210032110, Length=182, Percent_Identity=26.3736263736264, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=244, Percent_Identity=27.4590163934426, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082100, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787335, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787905, Length=142, Percent_Identity=33.8028169014084, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789208, Length=186, Percent_Identity=30.1075268817204, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790717, Length=194, Percent_Identity=26.8041237113402, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786701, Length=272, Percent_Identity=28.6764705882353, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=255, Percent_Identity=27.843137254902, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17567345, Length=212, Percent_Identity=28.3018867924528, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=220, Percent_Identity=33.1818181818182, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=203, Percent_Identity=26.6009852216749, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=241, Percent_Identity=27.8008298755187, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=171, Percent_Identity=29.2397660818713, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=172, Percent_Identity=34.3023255813954, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=199, Percent_Identity=26.6331658291457, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=197, Percent_Identity=27.9187817258883, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=172, Percent_Identity=33.7209302325581, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=241, Percent_Identity=27.8008298755187, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=176, Percent_Identity=30.1136363636364, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=248, Percent_Identity=26.2096774193548, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=249, Percent_Identity=25.7028112449799, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=199, Percent_Identity=29.1457286432161, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25152911, Length=195, Percent_Identity=30.2564102564103, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=173, Percent_Identity=32.3699421965318, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=205, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=173, Percent_Identity=32.9479768786127, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=223, Percent_Identity=26.457399103139, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=168, Percent_Identity=32.1428571428571, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=25.3807106598985, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21358495, Length=280, Percent_Identity=30, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24584744, Length=238, Percent_Identity=32.7731092436975, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28574402, Length=238, Percent_Identity=32.7731092436975, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640492, Length=256, Percent_Identity=25.78125, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161076933, Length=219, Percent_Identity=29.2237442922374, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24584748, Length=219, Percent_Identity=29.2237442922374, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640442, Length=205, Percent_Identity=30.7317073170732, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356301, Length=210, Percent_Identity=29.0476190476191, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648944, Length=174, Percent_Identity=31.6091954022989, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364892, Length=248, Percent_Identity=23.7903225806452, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007236, Length=220, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=31.2820512820513, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=196, Percent_Identity=31.6326530612245, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=240, Percent_Identity=27.9166666666667, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007238, Length=178, Percent_Identity=30.8988764044944, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=181, Percent_Identity=33.1491712707182, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007234, Length=84, Percent_Identity=45.2380952380952, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007232, Length=84, Percent_Identity=45.2380952380952, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=31.0880829015544, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31650; Mature: 31518

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSKNPLRRLSDSLMLTSMRPSMAEQFLQPRADVDLTGKRILLTGASSGIGEAAAEKFARR
CCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHC
GATVVAVARRQDLLDALVGRISEAGGVAAARACDLSDLDAVDELVADVEERFGGVDILIN
CCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEE
NAGKSIRRPLAESLDRWHDVERTMTLNYYSPLRLIRGLAPGMIARGEGHIINVATWGVFS
CCCHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHCCCCCEECCCCCEEEEEECCCCC
EASPLFGVYVASKAALSAVSRVIETEWADKSVHSSTLYYPLVKTPMIAPTREYDRVPGLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCCCCCHHHHCCCCCC
PQEAADWMIAAARHRPVRIAPRMAVTARAVDSLAPTWFNAIVKRQQFQPGA
HHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKNPLRRLSDSLMLTSMRPSMAEQFLQPRADVDLTGKRILLTGASSGIGEAAAEKFARR
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHC
GATVVAVARRQDLLDALVGRISEAGGVAAARACDLSDLDAVDELVADVEERFGGVDILIN
CCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEE
NAGKSIRRPLAESLDRWHDVERTMTLNYYSPLRLIRGLAPGMIARGEGHIINVATWGVFS
CCCHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHCCCCCEECCCCCEEEEEECCCCC
EASPLFGVYVASKAALSAVSRVIETEWADKSVHSSTLYYPLVKTPMIAPTREYDRVPGLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCCCCCHHHHCCCCCC
PQEAADWMIAAARHRPVRIAPRMAVTARAVDSLAPTWFNAIVKRQQFQPGA
HHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA