Click here to switch to the map view.

The map label for this gene is menB [H]

Identifier: 108797714

GI number: 108797714

Start: 781291

End: 782202

Strand: Reverse

Name: menB [H]

Synonym: Mmcs_0735

Alternate gene names: 108797714

Gene position: 782202-781291 (Counterclockwise)

Preceding gene: 108797715

Following gene: 108797711

Centisome position: 13.71

GC content: 69.74

Gene sequence:

>912_bases
ATGAGCGACAACCCCTTCGACCCGTCAGTCTGGCAACCGGTTCCCGGCTTCGACCTGACCGACACCACCTACCACCGCCA
CGTCGTCGACGGTGTCGCGCAGCCGACCGTGCGCGTGGCCTTCGACCGGCCCGAGGTGCGCAACGCGTTCCGCCCGCACA
CCGTCGACGAGTTGTACCGGGTGCTCGACCACGCCCGGATGTCGCCCGATGTCGGCGTGGTGCTGCTCACCGGCAACGGT
CCGTCGGCCAAGGACGGCGGCTGGGCGTTCTGCTCCGGCGGCGACCAGCGCATCCGCGGGCGCTCCGGCTACCAGTACGC
CGCCGGCGAAACCGCCGAGACGGTCGACCCGGCCCGCGCGGGCCGGCTGCACATCCTCGAGGTGCAGCGCCTCATCCGGT
TCATGCCCAAGGTGGTGATCTGCCTGGTCAATGGGTGGGCGGCCGGCGGCGGGCACAGCCTGCACGTCACCTGCGACCTC
ACCCTGGCCAGCCGCCAGCACGCCCGGTTCAAGCAGACCGACGCCGACGTCGGCAGCTTCGACGGCGGCTTCGGCAGCGC
CTACCTCGCACGGCAGACCGGGCAGAAGTTCGCCCGCGAGATCTTCTTCCTCGGCCGCGCCTACGACGCCGAGACGATGT
ATCAGATGGGCGCGGTCAACGCCGTCGTCGACCACGCCGAACTCGAATCCGAGGCGCTGCAGTGGGCCGCCGAGATCAAC
GGCAAGTCCCCGCAGGCGGTGCGCATGCTGAAATTCTCGTTCAACCTCATCGACGACGGGTTGGTCGGCCAGCAGGTGTT
CGCCGGTGAGGCGACGCGGCTGGCGTACATGACCGACGAGGCCGTCGAGGGACGCGACGCGTTCCTGGAGAAGCGCGACC
CGGACTGGTCGGCCTTCCCGCGCTACTTCTGA

Upstream 100 bases:

>100_bases
ACGCCGGGTTGGTCACCGACGCGACGCCCGACGAGTTCGAGGCGCTGGCCGGCCGCTGCGCCGTCTTCCGCTTCGACCCG
ATCACGTAGGTTCTGTTGCC

Downstream 100 bases:

>100_bases
CAGGCGATCTACACGAACGACTTCAGCTCGCGGCGGCGCATCTTCTGGATCACCTCGTGGTGGCGCCGTGCGTGGTAGGC
CAGCGGGGTGTACGAGATGC

Product: naphthoate synthase

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSDNPFDPSVWQPVPGFDLTDTTYHRHVVDGVAQPTVRVAFDRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNG
PSAKDGGWAFCSGGDQRIRGRSGYQYAAGETAETVDPARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVTCDL
TLASRQHARFKQTDADVGSFDGGFGSAYLARQTGQKFAREIFFLGRAYDAETMYQMGAVNAVVDHAELESEALQWAAEIN
GKSPQAVRMLKFSFNLIDDGLVGQQVFAGEATRLAYMTDEAVEGRDAFLEKRDPDWSAFPRYF

Sequences:

>Translated_303_residues
MSDNPFDPSVWQPVPGFDLTDTTYHRHVVDGVAQPTVRVAFDRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNG
PSAKDGGWAFCSGGDQRIRGRSGYQYAAGETAETVDPARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVTCDL
TLASRQHARFKQTDADVGSFDGGFGSAYLARQTGQKFAREIFFLGRAYDAETMYQMGAVNAVVDHAELESEALQWAAEIN
GKSPQAVRMLKFSFNLIDDGLVGQQVFAGEATRLAYMTDEAVEGRDAFLEKRDPDWSAFPRYF
>Mature_302_residues
SDNPFDPSVWQPVPGFDLTDTTYHRHVVDGVAQPTVRVAFDRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGP
SAKDGGWAFCSGGDQRIRGRSGYQYAAGETAETVDPARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVTCDLT
LASRQHARFKQTDADVGSFDGGFGSAYLARQTGQKFAREIFFLGRAYDAETMYQMGAVNAVVDHAELESEALQWAAEING
KSPQAVRMLKFSFNLIDDGLVGQQVFAGEATRLAYMTDEAVEGRDAFLEKRDPDWSAFPRYF

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=268, Percent_Identity=28.7313432835821, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI31542718, Length=264, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1788597, Length=302, Percent_Identity=45.6953642384106, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI87082183, Length=267, Percent_Identity=25.4681647940075, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787659, Length=269, Percent_Identity=26.3940520446097, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI221142681, Length=266, Percent_Identity=27.4436090225564, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787660, Length=274, Percent_Identity=28.4671532846715, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=273, Percent_Identity=26.7399267399267, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=234, Percent_Identity=29.0598290598291, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25145438, Length=274, Percent_Identity=27.3722627737226, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24653139, Length=291, Percent_Identity=26.8041237113402, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129971, Length=279, Percent_Identity=25.4480286738351, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653477, Length=279, Percent_Identity=25.4480286738351, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 33478; Mature: 33347

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNPFDPSVWQPVPGFDLTDTTYHRHVVDGVAQPTVRVAFDRPEVRNAFRPHTVDELYR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCHHHHHH
VLDHARMSPDVGVVLLTGNGPSAKDGGWAFCSGGDQRIRGRSGYQYAAGETAETVDPARA
HHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCEECCCCCCHHCCHHHC
GRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVTCDLTLASRQHARFKQTDADVGSF
CCEEHHHHHHHHHHHHHHEEHEECCCCCCCCCEEEEEEEEEECCCHHHHHHCCCCCCCCC
DGGFGSAYLARQTGQKFAREIFFLGRAYDAETMYQMGAVNAVVDHAELESEALQWAAEIN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKSPQAVRMLKFSFNLIDDGLVGQQVFAGEATRLAYMTDEAVEGRDAFLEKRDPDWSAFP
CCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEECCHHHCCHHHHHHCCCCCCCCCC
RYF
CCC
>Mature Secondary Structure 
SDNPFDPSVWQPVPGFDLTDTTYHRHVVDGVAQPTVRVAFDRPEVRNAFRPHTVDELYR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCHHHHHH
VLDHARMSPDVGVVLLTGNGPSAKDGGWAFCSGGDQRIRGRSGYQYAAGETAETVDPARA
HHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCEECCCCCCHHCCHHHC
GRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVTCDLTLASRQHARFKQTDADVGSF
CCEEHHHHHHHHHHHHHHEEHEECCCCCCCCCEEEEEEEEEECCCHHHHHHCCCCCCCCC
DGGFGSAYLARQTGQKFAREIFFLGRAYDAETMYQMGAVNAVVDHAELESEALQWAAEIN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKSPQAVRMLKFSFNLIDDGLVGQQVFAGEATRLAYMTDEAVEGRDAFLEKRDPDWSAFP
CCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEECCHHHCCHHHHHHCCCCCCCCCC
RYF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA