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The map label for this gene is senX3 [H]

Identifier: 108797640

GI number: 108797640

Start: 721179

End: 722357

Strand: Direct

Name: senX3 [H]

Synonym: Mmcs_0660

Alternate gene names: 108797640

Gene position: 721179-722357 (Clockwise)

Preceding gene: 108797639

Following gene: 108797641

Centisome position: 12.64

GC content: 68.7

Gene sequence:

>1179_bases
GTGAGTGTGGCATCCGCACTGCTGATGACGGCAGTCGTGGCGCTACTCACGCTGCTGGTGGGCGTGGGAGTGGGCGTCGC
GCTCACCCCTCGGGTGGCGGAGCGCCGTCGGCGGCGGGCGGCCGAGACGGCGGGGATCACCGTGTCGCAGATGCTCGCCC
ACATCGTCTCGTCATCGCCCGTCGGCATCGTCGTCGTCGACAAATTCCGTGACGTGGTCTACAGCAATGTGCGGGCAGAG
GAGCTGGGCCTGGTCCGGGACCGGCTGCTCGACGAACGGGCGTGGGAAGCCGCGCAGCACACGCTGAGCACCGGTGAGGA
CGTCCAGGTCGACCTGTCCCCGCGTAAGGTCGCCCACCCCGGCCGCTCCGGGCTGTCGGTGCGCGGCGCGGCGCGGTTGC
TGACCAGGGCGGACCGCCGGTTCGCGGTGGTCTACGTCGACGACCACTCCGAATATGCCCGGATGGAAGCCACACGCAGG
GACTTCGTGGCCAACGTCAGCCACGAACTCAAGACCCCGGTCGGGGCGATGGGCCTACTCGCCGAGGCGTTGCTGGCCTC
CGCCGACGACCCCGAGACCGTGCGCCGCTTCGCCGGGAAGATGGTCGACGAAGCGCATCGACTCGCCGACATGATCGGCG
AACTGATCGAACTGTCCCGCCTGCAGGGCGGTGAGCGGCTGCCCGACCTCGGCGTCGTGGACGTCGACACCGTCGTCTCC
GAAGCGCTGTCGCGCCACAAGGTGGCCGCCGACAACGCCGACATCGCGATCACCACCGATGCGCCGACCGGCTTCAAGGT
GCTGGGCGACCAGACGCTGCTGGTGGCCGCGCTGGCCAACCTGGTCTCCAACGCGATCGCCTACTCGCCGCGGGGGACCC
CGGTGTCGGTGAGCCGGCGGCGTCGGGGCGACAACATCGAGATCTCGGTCACCGACCGCGGCATCGGTATCGACAAAGAC
GATCAGGAGCGGGTCTTCGAACGCTTCTTCCGCGTCGACAAGGCCCGCTCGCGGGCGACCGGCGGTACCGGTCTGGGCCT
GGCGATCGTCAAACACGTCGCCGCCAATCACAACGGAGCCATCCGGCTGTGGAGTCAGCCGGGCACCGGATCGACGTTCA
CCCTGTCGATTCCGGCCTACCCGCGACCTGAGGAAGTAGACGATGAACCGAGTCAATAG

Upstream 100 bases:

>100_bases
CGGTGAACTGCGGCCGAACTCCTGCGATTCGCGGTGTGACTTGTCTCGATTTGGCCGCACGCTGCTGGGATGACGTTCAC
CGCATGCGTACGATTTCGCT

Downstream 100 bases:

>100_bases
GAGGACCCGAGACCAATGACCAGTGTGTTGATCGTGGAGGACGAGGAGTCCTTGGCCGATCCCCTGGCCTTCCTGCTGCG
CAAAGAGGGCTTCGAGACCA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSVASALLMTAVVALLTLLVGVGVGVALTPRVAERRRRRAAETAGITVSQMLAHIVSSSPVGIVVVDKFRDVVYSNVRAE
ELGLVRDRLLDERAWEAAQHTLSTGEDVQVDLSPRKVAHPGRSGLSVRGAARLLTRADRRFAVVYVDDHSEYARMEATRR
DFVANVSHELKTPVGAMGLLAEALLASADDPETVRRFAGKMVDEAHRLADMIGELIELSRLQGGERLPDLGVVDVDTVVS
EALSRHKVAADNADIAITTDAPTGFKVLGDQTLLVAALANLVSNAIAYSPRGTPVSVSRRRRGDNIEISVTDRGIGIDKD
DQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGAIRLWSQPGTGSTFTLSIPAYPRPEEVDDEPSQ

Sequences:

>Translated_392_residues
MSVASALLMTAVVALLTLLVGVGVGVALTPRVAERRRRRAAETAGITVSQMLAHIVSSSPVGIVVVDKFRDVVYSNVRAE
ELGLVRDRLLDERAWEAAQHTLSTGEDVQVDLSPRKVAHPGRSGLSVRGAARLLTRADRRFAVVYVDDHSEYARMEATRR
DFVANVSHELKTPVGAMGLLAEALLASADDPETVRRFAGKMVDEAHRLADMIGELIELSRLQGGERLPDLGVVDVDTVVS
EALSRHKVAADNADIAITTDAPTGFKVLGDQTLLVAALANLVSNAIAYSPRGTPVSVSRRRRGDNIEISVTDRGIGIDKD
DQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGAIRLWSQPGTGSTFTLSIPAYPRPEEVDDEPSQ
>Mature_391_residues
SVASALLMTAVVALLTLLVGVGVGVALTPRVAERRRRRAAETAGITVSQMLAHIVSSSPVGIVVVDKFRDVVYSNVRAEE
LGLVRDRLLDERAWEAAQHTLSTGEDVQVDLSPRKVAHPGRSGLSVRGAARLLTRADRRFAVVYVDDHSEYARMEATRRD
FVANVSHELKTPVGAMGLLAEALLASADDPETVRRFAGKMVDEAHRLADMIGELIELSRLQGGERLPDLGVVDVDTVVSE
ALSRHKVAADNADIAITTDAPTGFKVLGDQTLLVAALANLVSNAIAYSPRGTPVSVSRRRRGDNIEISVTDRGIGIDKDD
QERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGAIRLWSQPGTGSTFTLSIPAYPRPEEVDDEPSQ

Specific function: Part of the two-component regulatory system senX3/regX3. Phosphorylates regX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to senX3 by the pstSCAB phosphate transporter system [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=34.8936170212766, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=32.1739130434783, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI48994928, Length=279, Percent_Identity=30.1075268817204, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=32.6446280991736, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=28.3261802575107, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693157, Length=401, Percent_Identity=26.6832917705736, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=26.2443438914027, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=33.0316742081448, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788549, Length=356, Percent_Identity=27.5280898876405, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=31.5533980582524, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=27.3127753303965, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=27.7533039647577, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789403, Length=208, Percent_Identity=30.2884615384615, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=26.8774703557312, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=219, Percent_Identity=26.027397260274, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790551, Length=222, Percent_Identity=28.8288288288288, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=228, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=73, Percent_Identity=46.5753424657534, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42244; Mature: 42112

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVASALLMTAVVALLTLLVGVGVGVALTPRVAERRRRRAAETAGITVSQMLAHIVSSSP
CCHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
VGIVVVDKFRDVVYSNVRAEELGLVRDRLLDERAWEAAQHTLSTGEDVQVDLSPRKVAHP
CEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHCCC
GRSGLSVRGAARLLTRADRRFAVVYVDDHSEYARMEATRRDFVANVSHELKTPVGAMGLL
CCCCCCHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AEALLASADDPETVRRFAGKMVDEAHRLADMIGELIELSRLQGGERLPDLGVVDVDTVVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
EALSRHKVAADNADIAITTDAPTGFKVLGDQTLLVAALANLVSNAIAYSPRGTPVSVSRR
HHHHHHHCCCCCCCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHEECCCCCCCCHHHH
RRGDNIEISVTDRGIGIDKDDQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGA
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCE
IRLWSQPGTGSTFTLSIPAYPRPEEVDDEPSQ
EEEECCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVASALLMTAVVALLTLLVGVGVGVALTPRVAERRRRRAAETAGITVSQMLAHIVSSSP
CHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
VGIVVVDKFRDVVYSNVRAEELGLVRDRLLDERAWEAAQHTLSTGEDVQVDLSPRKVAHP
CEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHCCC
GRSGLSVRGAARLLTRADRRFAVVYVDDHSEYARMEATRRDFVANVSHELKTPVGAMGLL
CCCCCCHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AEALLASADDPETVRRFAGKMVDEAHRLADMIGELIELSRLQGGERLPDLGVVDVDTVVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
EALSRHKVAADNADIAITTDAPTGFKVLGDQTLLVAALANLVSNAIAYSPRGTPVSVSRR
HHHHHHHCCCCCCCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHEECCCCCCCCHHHH
RRGDNIEISVTDRGIGIDKDDQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGA
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCE
IRLWSQPGTGSTFTLSIPAYPRPEEVDDEPSQ
EEEECCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA