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The map label for this gene is regX3 [H]

Identifier: 108797641

GI number: 108797641

Start: 722373

End: 723059

Strand: Direct

Name: regX3 [H]

Synonym: Mmcs_0661

Alternate gene names: 108797641

Gene position: 722373-723059 (Clockwise)

Preceding gene: 108797640

Following gene: 108797644

Centisome position: 12.66

GC content: 67.69

Gene sequence:

>687_bases
ATGACCAGTGTGTTGATCGTGGAGGACGAGGAGTCCTTGGCCGATCCCCTGGCCTTCCTGCTGCGCAAAGAGGGCTTCGA
GACCACCGTGGTGGCCGACGGACCCTCGGCGCTGGCCGAGTTCGACCGCGCCGGCGCCGACATCGTGCTGCTGGATCTGA
TGCTGCCCGGAATGAGCGGCACCGACGTCTGCAAGCAACTGCGCGCCCGGTCCAGCGTGCCGGTCATCATGGTGACCGCC
CGCGACAGCGAGATCGACAAGGTCGTCGGGCTCGAACTCGGCGCCGACGACTATGTCACCAAACCGTATTCGGCCCGCGA
ACTGATCGCGCGGATCCGGGCGGTGCTGCGCCGCGGCACCGACGTCGACGACCCCGGCGTCCCCGACGGGGTGCTGGAGG
CCGGACCCGTGCGGATGGACGTCGAGCGCCACGTGGTCAGCGTCAACGGCCAGTCGATCACGTTGCCGCTCAAGGAGTTC
GACCTCCTCGAGTACCTGATGCGCAACAGCGGCCGGGTGCTGACGCGCGGTCAGCTCATCGACCGGGTGTGGGGTGCGGA
CTACGTCGGTGACACCAAGACCCTCGACGTCCACGTCAAGCGGCTGCGGTCGAAGATCGAGGCGGATCCGGCGAACCCGG
TGCACCTGGTCACGGTGCGCGGTCTGGGATACAAGCTCGAGGGCTGA

Upstream 100 bases:

>100_bases
TCAGCCGGGCACCGGATCGACGTTCACCCTGTCGATTCCGGCCTACCCGCGACCTGAGGAAGTAGACGATGAACCGAGTC
AATAGGAGGACCCGAGACCA

Downstream 100 bases:

>100_bases
ACCCGCCCGACGCCGGACACCTATCCGGTTGTGCCGCCCATGATCTCGAACACCTCGAAGGTGTTCACCCAGGCGAGGAC
CGAGGGGTCGTGTCGGCCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTSVLIVEDEESLADPLAFLLRKEGFETTVVADGPSALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTA
RDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGTDVDDPGVPDGVLEAGPVRMDVERHVVSVNGQSITLPLKEF
DLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG

Sequences:

>Translated_228_residues
MTSVLIVEDEESLADPLAFLLRKEGFETTVVADGPSALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTA
RDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGTDVDDPGVPDGVLEAGPVRMDVERHVVSVNGQSITLPLKEF
DLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
>Mature_227_residues
TSVLIVEDEESLADPLAFLLRKEGFETTVVADGPSALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTAR
DSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGTDVDDPGVPDGVLEAGPVRMDVERHVVSVNGQSITLPLKEFD
LLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=39.647577092511, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=38.7665198237885, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=37.7777777777778, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=37.6106194690265, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=38.4279475982533, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=37.6681614349776, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=38.4955752212389, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=40.174672489083, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=36.6071428571429, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.3275862068966, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=36.5217391304348, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=34.2222222222222, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=31.4655172413793, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=35.7798165137615, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24908; Mature: 24777

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVLIVEDEESLADPLAFLLRKEGFETTVVADGPSALAEFDRAGADIVLLDLMLPGMSG
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCH
TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGT
HHHHHHHHHCCCCCEEEEEECCCCCHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
DVDDPGVPDGVLEAGPVRMDVERHVVSVNGQSITLPLKEFDLLEYLMRNSGRVLTRGQLI
CCCCCCCCCCCCCCCCEEEECCCEEEEECCCEEEEEHHHHHHHHHHHHCCCCEEEHHHHH
DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECC
>Mature Secondary Structure 
TSVLIVEDEESLADPLAFLLRKEGFETTVVADGPSALAEFDRAGADIVLLDLMLPGMSG
CEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCH
TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGT
HHHHHHHHHCCCCCEEEEEECCCCCHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
DVDDPGVPDGVLEAGPVRMDVERHVVSVNGQSITLPLKEFDLLEYLMRNSGRVLTRGQLI
CCCCCCCCCCCCCCCCEEEECCCEEEEECCCEEEEEHHHHHHHHHHHHCCCCEEEHHHHH
DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA