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The map label for this gene is mrpC [H]

Identifier: 108797565

GI number: 108797565

Start: 643280

End: 643753

Strand: Reverse

Name: mrpC [H]

Synonym: Mmcs_0585

Alternate gene names: 108797565

Gene position: 643753-643280 (Counterclockwise)

Preceding gene: 108797566

Following gene: 108797564

Centisome position: 11.28

GC content: 67.09

Gene sequence:

>474_bases
GTGACCACCTTCCTCGTTCCCCTGATCCTGATCGGCGGCCTCACCAGCGTGGGTGTCTACCTGCTGCTCGAGCGCAACCT
CACCCGAATGTTGTTGGGGCTGTTGCTGATCGGTAATGCCATCAATCTGCTCATCCTCACGGTGGCCGGACCGTCCGGCA
ATCCGCCGGTGCGGGGGCGCACCAAGGCCGGGGAGACCACCACGGCGGATCCGTTGGCGCAGGGCATGATCCTCACCGCG
ATCGTCATCAGCATGGGCATCGCGGCGTTCGTCCTGGCGCTCACCTACCGGTCCTATCGACTGACCACCGCCGAAGATGT
CGGCAACGACCCCGAGGACACCCGCGTGTCGTCGATGGCCGCCAAGGAGGCCGCCGCCCTCGACGAGGACCGCCCACCCG
AACCGGATCTGGCCATCGACACCGACCTGCCCGACGAACTCGACGCGCTACCCGGTCGGGAGGGGTCCCGGTGA

Upstream 100 bases:

>100_bases
TGGTCCTCGATGTACTGCGCAGCCTGGGCGCTCAGGTCGACGTGGAGATGTCCCAACCGAACCCCGGTTCGGGCGGGTCC
GCGGCGAAGGTCGGTGCGCG

Downstream 100 bases:

>100_bases
GTCTCAGCTCGGTGCTCACGCCCCTGCCGGTGCTCATCCCGACGATCGCGGCCGCGCTGACGCTGTTCGCGGGCCGCCGC
CCGGTGTTGCAGCGGGTGAT

Product: putative monovalent cation/H+ antiporter subunit C

Products: NA

Alternate protein names: Mrp complex subunit C; Multiple resistance and pH homeostasis protein C [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MTTFLVPLILIGGLTSVGVYLLLERNLTRMLLGLLLIGNAINLLILTVAGPSGNPPVRGRTKAGETTTADPLAQGMILTA
IVISMGIAAFVLALTYRSYRLTTAEDVGNDPEDTRVSSMAAKEAAALDEDRPPEPDLAIDTDLPDELDALPGREGSR

Sequences:

>Translated_157_residues
MTTFLVPLILIGGLTSVGVYLLLERNLTRMLLGLLLIGNAINLLILTVAGPSGNPPVRGRTKAGETTTADPLAQGMILTA
IVISMGIAAFVLALTYRSYRLTTAEDVGNDPEDTRVSSMAAKEAAALDEDRPPEPDLAIDTDLPDELDALPGREGSR
>Mature_156_residues
TTFLVPLILIGGLTSVGVYLLLERNLTRMLLGLLLIGNAINLLILTVAGPSGNPPVRGRTKAGETTTADPLAQGMILTAI
VISMGIAAFVLALTYRSYRLTTAEDVGNDPEDTRVSSMAAKEAAALDEDRPPEPDLAIDTDLPDELDALPGREGSR

Specific function: Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential, and is thus inferred to be electrogenic. Does not transport K(+), Ca(2+) or Mg(2+

COG id: COG1006

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhC subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001133 [H]

Pfam domain/function: PF00420 Oxidored_q2 [H]

EC number: NA

Molecular weight: Translated: 16570; Mature: 16439

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFLVPLILIGGLTSVGVYLLLERNLTRMLLGLLLIGNAINLLILTVAGPSGNPPVRGR
CCHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHCHHEEEEEEEECCCCCCCCCCC
TKAGETTTADPLAQGMILTAIVISMGIAAFVLALTYRSYRLTTAEDVGNDPEDTRVSSMA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHH
AKEAAALDEDRPPEPDLAIDTDLPDELDALPGREGSR
HHHHHHCCCCCCCCCCEEECCCCCHHHHCCCCCCCCC
>Mature Secondary Structure 
TTFLVPLILIGGLTSVGVYLLLERNLTRMLLGLLLIGNAINLLILTVAGPSGNPPVRGR
CHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHCHHEEEEEEEECCCCCCCCCCC
TKAGETTTADPLAQGMILTAIVISMGIAAFVLALTYRSYRLTTAEDVGNDPEDTRVSSMA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHH
AKEAAALDEDRPPEPDLAIDTDLPDELDALPGREGSR
HHHHHHCCCCCCCCCCEEECCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]