Click here to switch to the map view.

The map label for this gene is rutG [H]

Identifier: 108797536

GI number: 108797536

Start: 616975

End: 618276

Strand: Reverse

Name: rutG [H]

Synonym: Mmcs_0556

Alternate gene names: 108797536

Gene position: 618276-616975 (Counterclockwise)

Preceding gene: 108797537

Following gene: 108797531

Centisome position: 10.84

GC content: 69.05

Gene sequence:

>1302_bases
GTGATCCCAGCCAAGACCGGTCGGTCGGCGAACTGGAAGTGGAAGCCCGTCGAAGCGCGCGCGGACGCCGATTTCGTCGT
CGCCCCGGACGAGCGCCTGAGCTGGCCCCGCACCATCGGCCTGGGCGCTCAGCACGTGGTGGCGATGTTCGGTGCCACGT
TCCTGGTGCCGGTGCTGACCGGCTTCCCGCCCGCCACCACCCTGCTGTTCTCCGGTGTGGGCACGATCCTGTTCCTGATC
ATCACGGGCAACCGGCTGCCCAGCTACCTGGGCTCGAGCTTCTCGGTGATCGCGCCCGTCACGGCGGCCGTCGCGTCGGA
GGGCACGGGCAGCGCGCTCGGAGGCATCGTCGCACTCGGACTGGTGCTGATCGTCATCGGCGGCGTCGTCCACCTCGTCG
GCACCCGCTGGCTCGACGTCACCCTGCCGCCGGTCGTCACCGGTGCGATCGTCGCGCTGATCGGGTTCAACCTCGCACCC
GCCGCCAAGACGAACTTCGAGGCCGGGCCCGTCGTCGCCACCGTCACGCTGGTGCTGTTGGTCGCGACGTTGGCGTTCTT
CCGCGGGATGATCGGCCGGTTGGCGATCTTCCTCGCGGTGCTGATCGGGTATCTGCTCGCATTGGCGATGGGCGACGTCG
ACACCTCGGCGATCGCGGCGGCCCCCTGGGTCGGTCTACCCGACTTCGAGGCGCCGTCGTTCTCGCTCGCAGTGCTGCCG
ATGTTCCTGCCCGCCGTGGTCGCGCTGATCGCCGAGAACATCGGCCATGTGAAGTCGGTCGGTCAGATGACCAGAACCGA
CATGGATCCGCTCATCGGGCGGGCACTCGCCGCCGACGGTGTCGCGACCACGCTGGCCGGTTTCGGGGGCGGATCGGCGA
CCACGACGTACGCGGAGAACATCGGCGTCATGGCCGCCACCCGCGTGTACTCGACGGCCGCGTACTGGGTGGCAGCGGTG
GTGGCCATCGCGCTGTCGCTGTGCCCGAAGATCGGGGCGGCGATCTCGGCCACCCCGGCCGGTGTGCTCGGCGGCGCGAC
CGTGGTGCTCTACGGGTTGGTGGGCGTGCTCGGTGTGCGGATCTGGTTGACCAACCACGTCGACTTCTCGCTGCCGGTCA
ACCAGATGACCGCGGCCATCCCACTCATCATCGGCATCGCCGACTTCACTTGGCAGGCAGGCGAACTCACGTTCACCGGG
ATCGCGCTCGGCTCGATCGCGGCGCTGCTGGTCTACCACGGGATGCGCCTGCTGGGCCTGCGCACGAGCAGATCTGCCGA
GCCCTCCACCTCCACCGTGTGA

Upstream 100 bases:

>100_bases
GACGTCCGTGCTCGCCGGCGTCGCCGTGCTCGCGGTGGGCGCGCTGGCCTATGCGGTACGCCGCGCGCGGAGCACCGGCA
ACGGTGCAAGATAGGCAACC

Downstream 100 bases:

>100_bases
GGCCGGACGGAACGGCTCTACTCGGCGTCGCCCGACGTCGAGTCGGACCCCGAACCGCTGCCCGAGTCCGACCCCGAGTC
GCTCTCGGACGCCGAGCCGC

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIPAKTGRSANWKWKPVEARADADFVVAPDERLSWPRTIGLGAQHVVAMFGATFLVPVLTGFPPATTLLFSGVGTILFLI
ITGNRLPSYLGSSFSVIAPVTAAVASEGTGSALGGIVALGLVLIVIGGVVHLVGTRWLDVTLPPVVTGAIVALIGFNLAP
AAKTNFEAGPVVATVTLVLLVATLAFFRGMIGRLAIFLAVLIGYLLALAMGDVDTSAIAAAPWVGLPDFEAPSFSLAVLP
MFLPAVVALIAENIGHVKSVGQMTRTDMDPLIGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAAYWVAAV
VAIALSLCPKIGAAISATPAGVLGGATVVLYGLVGVLGVRIWLTNHVDFSLPVNQMTAAIPLIIGIADFTWQAGELTFTG
IALGSIAALLVYHGMRLLGLRTSRSAEPSTSTV

Sequences:

>Translated_433_residues
MIPAKTGRSANWKWKPVEARADADFVVAPDERLSWPRTIGLGAQHVVAMFGATFLVPVLTGFPPATTLLFSGVGTILFLI
ITGNRLPSYLGSSFSVIAPVTAAVASEGTGSALGGIVALGLVLIVIGGVVHLVGTRWLDVTLPPVVTGAIVALIGFNLAP
AAKTNFEAGPVVATVTLVLLVATLAFFRGMIGRLAIFLAVLIGYLLALAMGDVDTSAIAAAPWVGLPDFEAPSFSLAVLP
MFLPAVVALIAENIGHVKSVGQMTRTDMDPLIGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAAYWVAAV
VAIALSLCPKIGAAISATPAGVLGGATVVLYGLVGVLGVRIWLTNHVDFSLPVNQMTAAIPLIIGIADFTWQAGELTFTG
IALGSIAALLVYHGMRLLGLRTSRSAEPSTSTV
>Mature_433_residues
MIPAKTGRSANWKWKPVEARADADFVVAPDERLSWPRTIGLGAQHVVAMFGATFLVPVLTGFPPATTLLFSGVGTILFLI
ITGNRLPSYLGSSFSVIAPVTAAVASEGTGSALGGIVALGLVLIVIGGVVHLVGTRWLDVTLPPVVTGAIVALIGFNLAP
AAKTNFEAGPVVATVTLVLLVATLAFFRGMIGRLAIFLAVLIGYLLALAMGDVDTSAIAAAPWVGLPDFEAPSFSLAVLP
MFLPAVVALIAENIGHVKSVGQMTRTDMDPLIGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAAYWVAAV
VAIALSLCPKIGAAISATPAGVLGGATVVLYGLVGVLGVRIWLTNHVDFSLPVNQMTAAIPLIIGIADFTWQAGELTFTG
IALGSIAALLVYHGMRLLGLRTSRSAEPSTSTV

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=423, Percent_Identity=26.0047281323877, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI40316845, Length=423, Percent_Identity=26.0047281323877, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87081818, Length=419, Percent_Identity=46.3007159904535, Blast_Score=327, Evalue=8e-91,
Organism=Escherichia coli, GI1788843, Length=390, Percent_Identity=40.2564102564103, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI87082181, Length=365, Percent_Identity=26.8493150684932, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI87082178, Length=238, Percent_Identity=24.7899159663866, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790087, Length=456, Percent_Identity=25.219298245614, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17542262, Length=171, Percent_Identity=29.8245614035088, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356175, Length=419, Percent_Identity=25.2983293556086, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44311; Mature: 44311

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPAKTGRSANWKWKPVEARADADFVVAPDERLSWPRTIGLGAQHVVAMFGATFLVPVLT
CCCCCCCCCCCCEECCCCCCCCCCEEECCHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHH
GFPPATTLLFSGVGTILFLIITGNRLPSYLGSSFSVIAPVTAAVASEGTGSALGGIVALG
CCCHHHHHHHHHHHHHEEEEEECCCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
LVLIVIGGVVHLVGTRWLDVTLPPVVTGAIVALIGFNLAPAAKTNFEAGPVVATVTLVLL
HHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
VATLAFFRGMIGRLAIFLAVLIGYLLALAMGDVDTSAIAAAPWVGLPDFEAPSFSLAVLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCHHHHHH
MFLPAVVALIAENIGHVKSVGQMTRTDMDPLIGRALAADGVATTLAGFGGGSATTTYAEN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHH
IGVMAATRVYSTAAYWVAAVVAIALSLCPKIGAAISATPAGVLGGATVVLYGLVGVLGVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IWLTNHVDFSLPVNQMTAAIPLIIGIADFTWQAGELTFTGIALGSIAALLVYHGMRLLGL
HHEECCCCEECCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCHHHEEE
RTSRSAEPSTSTV
CCCCCCCCCCCCC
>Mature Secondary Structure
MIPAKTGRSANWKWKPVEARADADFVVAPDERLSWPRTIGLGAQHVVAMFGATFLVPVLT
CCCCCCCCCCCCEECCCCCCCCCCEEECCHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHH
GFPPATTLLFSGVGTILFLIITGNRLPSYLGSSFSVIAPVTAAVASEGTGSALGGIVALG
CCCHHHHHHHHHHHHHEEEEEECCCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
LVLIVIGGVVHLVGTRWLDVTLPPVVTGAIVALIGFNLAPAAKTNFEAGPVVATVTLVLL
HHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
VATLAFFRGMIGRLAIFLAVLIGYLLALAMGDVDTSAIAAAPWVGLPDFEAPSFSLAVLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCHHHHHH
MFLPAVVALIAENIGHVKSVGQMTRTDMDPLIGRALAADGVATTLAGFGGGSATTTYAEN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHH
IGVMAATRVYSTAAYWVAAVVAIALSLCPKIGAAISATPAGVLGGATVVLYGLVGVLGVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IWLTNHVDFSLPVNQMTAAIPLIIGIADFTWQAGELTFTGIALGSIAALLVYHGMRLLGL
HHEECCCCEECCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCHHHEEE
RTSRSAEPSTSTV
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]