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The map label for this gene is yhfM [C]

Identifier: 108797537

GI number: 108797537

Start: 618283

End: 619530

Strand: Reverse

Name: yhfM [C]

Synonym: Mmcs_0557

Alternate gene names: 108797537

Gene position: 619530-618283 (Counterclockwise)

Preceding gene: 108797538

Following gene: 108797536

Centisome position: 10.86

GC content: 74.52

Gene sequence:

>1248_bases
GTGAACCCACCCGGCGGGCCGGCGCTGTCGAGACGACTCGGTCTCGTCGACGCGATCGTCATCGGCCTGGGCGCCATGAT
CGGCGCCGGCATCTTCACCGCGCTCGCGCCTGCGGCGGCCGCCGCCGGTGGCGGCCTGCTGGTGGGGCTGGCCGTGGCGG
CGGTCGTCGCGTACTGCAACGCCACCTCCTCGGCGCGCCTGGCCGCGCGTTATCCGGAATCCGGCGGCACCTATGTCTAC
GGCCGGGAGCGACTGGGCCCGTTCTGGGGATATCTGGCGGGTTGGGGGTTCGTCGCGGGGAAGACCGCCTCGTGCGCGGC
GATGGCGCTGACCGTCGGCGTCTATGTCTGGCCCGGTGGCGCCCGCCTGATCGCGGTCGCCGCCGTGGTCGCGCTCACCG
CGGTCAACTACGCGGGCATCCGGAAATCGGCGCTGCTCACCCGCCTCATCGTCGCGGTCGTCCTGGCGGTGCTGGCCGTC
GTGGTGGTGATCGTCCTGGGGTTCGGGGATCCTGTCGGCGACCGGTTGGACTTCGGGGCGGACGTCACGGTCGGCGGCGC
ACTCCAGTCGGCCGGCCTGTTGTTCTTCGCGTTCGCCGGATACGCCCGCATCGCCACCCTGGGCGAGGAGGTATGCGACC
CGGCGCGCACCATCCCCCGCGCCATCCCGATCGCGCTGGGCCTCACGTTGGCGGTCTACGCCGTCGTGGCGGTCACCGTG
CTGGCCCAGTTGGGACCCGCGGCGCTGGCCGGCTCGACGGCGCCACTGGCCGATGCGGTCCGGGCGGCCGGGTTCCCGGG
CTGGGTCCCTGTCGTGGGCGCCGGCGCCGCGGTCGCCGCGCTCGGCTCGCTGCTCGCGCTGATTCTCGGCGTCTCGCGCA
CGGCGCTGGCGATGGCGCGCGACCGTCACCTGCCGTCCGGGTTGGCCGCCGTGCACGCCCGCCACGGCACCCCGCACCGC
GCGGAGGTCGCGGTGGGCGTGCTGGTCGCCGCGCTGGCGGCGACGGTGGATCTGCGCGACGCGATCGGCTTCTCGTCGTT
CGCGGTGCTGATGTACTACGCGATCGCCAACGCGTCGGCGTGGACGCTCGGCGCCCGGGTGGTGCCGGCGGTCGGACTGG
CCGGCTGCCTGCTGCTGGCGTTCGCGCTGCCGTGGACGTCCGTGCTCGCCGGCGTCGCCGTGCTCGCGGTGGGCGCGCTG
GCCTATGCGGTACGCCGCGCGCGGAGCACCGGCAACGGTGCAAGATAG

Upstream 100 bases:

>100_bases
CGGGGTCGTCGCCATGGTCGCGGTGTTGCTCACGGCAACGGTCGCCCACGAGGACGAGGACACGCTCGCCGGCGACCGGG
AGACTTCCTAGCATCACGGT

Downstream 100 bases:

>100_bases
GCAACCGTGATCCCAGCCAAGACCGGTCGGTCGGCGAACTGGAAGTGGAAGCCCGTCGAAGCGCGCGCGGACGCCGATTT
CGTCGTCGCCCCGGACGAGC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MNPPGGPALSRRLGLVDAIVIGLGAMIGAGIFTALAPAAAAAGGGLLVGLAVAAVVAYCNATSSARLAARYPESGGTYVY
GRERLGPFWGYLAGWGFVAGKTASCAAMALTVGVYVWPGGARLIAVAAVVALTAVNYAGIRKSALLTRLIVAVVLAVLAV
VVVIVLGFGDPVGDRLDFGADVTVGGALQSAGLLFFAFAGYARIATLGEEVCDPARTIPRAIPIALGLTLAVYAVVAVTV
LAQLGPAALAGSTAPLADAVRAAGFPGWVPVVGAGAAVAALGSLLALILGVSRTALAMARDRHLPSGLAAVHARHGTPHR
AEVAVGVLVAALAATVDLRDAIGFSSFAVLMYYAIANASAWTLGARVVPAVGLAGCLLLAFALPWTSVLAGVAVLAVGAL
AYAVRRARSTGNGAR

Sequences:

>Translated_415_residues
MNPPGGPALSRRLGLVDAIVIGLGAMIGAGIFTALAPAAAAAGGGLLVGLAVAAVVAYCNATSSARLAARYPESGGTYVY
GRERLGPFWGYLAGWGFVAGKTASCAAMALTVGVYVWPGGARLIAVAAVVALTAVNYAGIRKSALLTRLIVAVVLAVLAV
VVVIVLGFGDPVGDRLDFGADVTVGGALQSAGLLFFAFAGYARIATLGEEVCDPARTIPRAIPIALGLTLAVYAVVAVTV
LAQLGPAALAGSTAPLADAVRAAGFPGWVPVVGAGAAVAALGSLLALILGVSRTALAMARDRHLPSGLAAVHARHGTPHR
AEVAVGVLVAALAATVDLRDAIGFSSFAVLMYYAIANASAWTLGARVVPAVGLAGCLLLAFALPWTSVLAGVAVLAVGAL
AYAVRRARSTGNGAR
>Mature_415_residues
MNPPGGPALSRRLGLVDAIVIGLGAMIGAGIFTALAPAAAAAGGGLLVGLAVAAVVAYCNATSSARLAARYPESGGTYVY
GRERLGPFWGYLAGWGFVAGKTASCAAMALTVGVYVWPGGARLIAVAAVVALTAVNYAGIRKSALLTRLIVAVVLAVLAV
VVVIVLGFGDPVGDRLDFGADVTVGGALQSAGLLFFAFAGYARIATLGEEVCDPARTIPRAIPIALGLTLAVYAVVAVTV
LAQLGPAALAGSTAPLADAVRAAGFPGWVPVVGAGAAVAALGSLLALILGVSRTALAMARDRHLPSGLAAVHARHGTPHR
AEVAVGVLVAALAATVDLRDAIGFSSFAVLMYYAIANASAWTLGARVVPAVGLAGCLLLAFALPWTSVLAGVAVLAVGAL
AYAVRRARSTGNGAR

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=397, Percent_Identity=27.455919395466, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI258614005, Length=402, Percent_Identity=26.865671641791, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI258614003, Length=402, Percent_Identity=26.865671641791, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI114326544, Length=399, Percent_Identity=28.0701754385965, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI114326550, Length=399, Percent_Identity=28.0701754385965, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI258645169, Length=402, Percent_Identity=27.363184079602, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI186910308, Length=374, Percent_Identity=26.2032085561497, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI186910306, Length=374, Percent_Identity=26.2032085561497, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI186910304, Length=374, Percent_Identity=26.2032085561497, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI181337167, Length=397, Percent_Identity=28.9672544080605, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI33286428, Length=383, Percent_Identity=27.6762402088773, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI187423910, Length=370, Percent_Identity=24.8648648648649, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI7657591, Length=370, Percent_Identity=24.8648648648649, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI9790235, Length=315, Percent_Identity=26.031746031746, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI115648063, Length=372, Percent_Identity=24.7311827956989, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI115648022, Length=372, Percent_Identity=24.7311827956989, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI110347453, Length=381, Percent_Identity=27.8215223097113, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI71979932, Length=362, Percent_Identity=27.0718232044199, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI7657683, Length=325, Percent_Identity=25.5384615384615, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI33286430, Length=162, Percent_Identity=27.1604938271605, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87082250, Length=453, Percent_Identity=25.60706401766, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081869, Length=441, Percent_Identity=25.1700680272109, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786694, Length=350, Percent_Identity=26.8571428571429, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082023, Length=369, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367353, Length=333, Percent_Identity=27.9279279279279, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786789, Length=268, Percent_Identity=26.1194029850746, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786302, Length=347, Percent_Identity=23.9193083573487, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790575, Length=349, Percent_Identity=29.512893982808, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=400, Percent_Identity=26.75, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17532491, Length=408, Percent_Identity=28.1862745098039, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17533459, Length=380, Percent_Identity=26.0526315789474, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17540018, Length=414, Percent_Identity=24.6376811594203, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17568033, Length=344, Percent_Identity=26.453488372093, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=335, Percent_Identity=25.0746268656716, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993915, Length=372, Percent_Identity=24.7311827956989, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24667468, Length=397, Percent_Identity=28.9672544080605, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24668806, Length=394, Percent_Identity=25.8883248730964, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356285, Length=394, Percent_Identity=25.8883248730964, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24668802, Length=394, Percent_Identity=25.8883248730964, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221512776, Length=391, Percent_Identity=22.7621483375959, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24666159, Length=391, Percent_Identity=22.7621483375959, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24651635, Length=368, Percent_Identity=27.1739130434783, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24651633, Length=368, Percent_Identity=27.1739130434783, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221331183, Length=338, Percent_Identity=25.7396449704142, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17647653, Length=338, Percent_Identity=25.7396449704142, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24664379, Length=338, Percent_Identity=25.7396449704142, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281366235, Length=387, Percent_Identity=26.0981912144703, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI116007820, Length=387, Percent_Identity=26.0981912144703, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21357367, Length=361, Percent_Identity=26.0387811634349, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI116007818, Length=390, Percent_Identity=25.8974358974359, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI85725152, Length=390, Percent_Identity=25.8974358974359, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45550968, Length=372, Percent_Identity=24.1935483870968, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921172, Length=372, Percent_Identity=24.1935483870968, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641993, Length=365, Percent_Identity=23.2876712328767, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641995, Length=365, Percent_Identity=23.2876712328767, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161077963, Length=382, Percent_Identity=26.1780104712042, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 41188; Mature: 41188

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPGGPALSRRLGLVDAIVIGLGAMIGAGIFTALAPAAAAAGGGLLVGLAVAAVVAYCN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
ATSSARLAARYPESGGTYVYGRERLGPFWGYLAGWGFVAGKTASCAAMALTVGVYVWPGG
CCCCCHHHEECCCCCCCEEEEHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCC
ARLIAVAAVVALTAVNYAGIRKSALLTRLIVAVVLAVLAVVVVIVLGFGDPVGDRLDFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DVTVGGALQSAGLLFFAFAGYARIATLGEEVCDPARTIPRAIPIALGLTLAVYAVVAVTV
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAQLGPAALAGSTAPLADAVRAAGFPGWVPVVGAGAAVAALGSLLALILGVSRTALAMAR
HHHHCCHHHCCCCCHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DRHLPSGLAAVHARHGTPHRAEVAVGVLVAALAATVDLRDAIGFSSFAVLMYYAIANASA
HCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCH
WTLGARVVPAVGLAGCLLLAFALPWTSVLAGVAVLAVGALAYAVRRARSTGNGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPPGGPALSRRLGLVDAIVIGLGAMIGAGIFTALAPAAAAAGGGLLVGLAVAAVVAYCN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
ATSSARLAARYPESGGTYVYGRERLGPFWGYLAGWGFVAGKTASCAAMALTVGVYVWPGG
CCCCCHHHEECCCCCCCEEEEHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCC
ARLIAVAAVVALTAVNYAGIRKSALLTRLIVAVVLAVLAVVVVIVLGFGDPVGDRLDFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DVTVGGALQSAGLLFFAFAGYARIATLGEEVCDPARTIPRAIPIALGLTLAVYAVVAVTV
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAQLGPAALAGSTAPLADAVRAAGFPGWVPVVGAGAAVAALGSLLALILGVSRTALAMAR
HHHHCCHHHCCCCCHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DRHLPSGLAAVHARHGTPHRAEVAVGVLVAALAATVDLRDAIGFSSFAVLMYYAIANASA
HCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCH
WTLGARVVPAVGLAGCLLLAFALPWTSVLAGVAVLAVGALAYAVRRARSTGNGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]