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The map label for this gene is adhP [C]

Identifier: 108797482

GI number: 108797482

Start: 558128

End: 559141

Strand: Direct

Name: adhP [C]

Synonym: Mmcs_0502

Alternate gene names: 108797482

Gene position: 558128-559141 (Clockwise)

Preceding gene: 108797480

Following gene: 108797483

Centisome position: 9.78

GC content: 71.79

Gene sequence:

>1014_bases
ATGGCCACTCACAAAGCCGTCCACGTAGCCGCCGCGGGAGAACCGTTGACCCTCGCGGACGTCGAAACACCGTCTCCGCC
GCCCGGCCACCTGCGCATCGACGTCGCCGCCTGCGGCGTGTGCGGTACCGACCACGGGTTCGTCAACGGTAACTTCCCCG
GCCTGAGCTGGCCGATCACGCTCGGTCACGAGATCGCCGGCACCGTCGCCGAGCTGGGCGACGGGGTCGACGAGTTCGCC
GTCGGCGACCGGGTGGCCGTCGGCTGGTTCGGCGGCAACTGCAACAAGTGCATCCCGTGCCGCCGGGGTCTGTTCATGCA
GTGCGTCAACATGCAGGTGCCGAGTTGGCATTACCCCGGTGGCTACGCCGAATCGGTCGTCGTGCCCGCAACGGCGCCGG
CGCGCATCCCCGACGGGTTGTCGTTCGTCGAGGCGGCGCCGATGGGATGTGCGGGTGTCACCACGTTCAACGGGCTGCGC
CAGACCAGGGCCCGCGCCGGCGACCTGGTGGCCGTCCTCGGCATCGGCGGGCTCGGCCACCTCGGGGTGCAGTTCGCGCG
GGCGATGGGTTTCGAGACCGTCGCGATCGCCCGCGGGGCCGCCAAGGAGGACGACGCCCGGGCGCTGGGCGCCCACCACT
ACATCGACTCGACCGCCGGGGACGTCGCCGCGGCGTTGCAGAAGCTGGGCGGCGCCGCCGTGGTGCTCGCGACCGCGGCC
AGTTCGGCCGCGATGGGTCAGACGGTCGGCGGGCTGGGCCCGCAGGGGGAGCTGATCGTCGTGGGCGTCACCCCCGAACA
GCTGCCGATCAGCCCGCTCGATCTGATCAACTCGGGTCTGTCGGTGACCGGCCACCCGTCGGGCACCGCACGCGACGTCG
AGGAGACCATGCACTTCGCGGTGCTCTCCGGCGTGCGGGCGCGGGTCGAGGAGAAGCCGCTCGCCGAGGCCGCCGAGGCC
TACGCCGCGATGGACGAGGGCCGGGCCCGCTATCGCATGGTTCTCACCATGTGA

Upstream 100 bases:

>100_bases
GGGTGGTCGTCATGGGTACCCAAGATACCGGCCGAAAATTGCAGCTAGCCGGTGCGCATTCGGGCGGCGGCGCCGTGTTC
TCGTCATTAAGGTCCAAAAC

Downstream 100 bases:

>100_bases
TCACGCCCCGATAGGGGGATACTTCGTCGTATGCCGATCGCCACACCCGAGGTCTACGCCGAGATGCTCGACCGCGCCAA
GAAGCACTCGTTCGCGTTCC

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MATHKAVHVAAAGEPLTLADVETPSPPPGHLRIDVAACGVCGTDHGFVNGNFPGLSWPITLGHEIAGTVAELGDGVDEFA
VGDRVAVGWFGGNCNKCIPCRRGLFMQCVNMQVPSWHYPGGYAESVVVPATAPARIPDGLSFVEAAPMGCAGVTTFNGLR
QTRARAGDLVAVLGIGGLGHLGVQFARAMGFETVAIARGAAKEDDARALGAHHYIDSTAGDVAAALQKLGGAAVVLATAA
SSAAMGQTVGGLGPQGELIVVGVTPEQLPISPLDLINSGLSVTGHPSGTARDVEETMHFAVLSGVRARVEEKPLAEAAEA
YAAMDEGRARYRMVLTM

Sequences:

>Translated_337_residues
MATHKAVHVAAAGEPLTLADVETPSPPPGHLRIDVAACGVCGTDHGFVNGNFPGLSWPITLGHEIAGTVAELGDGVDEFA
VGDRVAVGWFGGNCNKCIPCRRGLFMQCVNMQVPSWHYPGGYAESVVVPATAPARIPDGLSFVEAAPMGCAGVTTFNGLR
QTRARAGDLVAVLGIGGLGHLGVQFARAMGFETVAIARGAAKEDDARALGAHHYIDSTAGDVAAALQKLGGAAVVLATAA
SSAAMGQTVGGLGPQGELIVVGVTPEQLPISPLDLINSGLSVTGHPSGTARDVEETMHFAVLSGVRARVEEKPLAEAAEA
YAAMDEGRARYRMVLTM
>Mature_336_residues
ATHKAVHVAAAGEPLTLADVETPSPPPGHLRIDVAACGVCGTDHGFVNGNFPGLSWPITLGHEIAGTVAELGDGVDEFAV
GDRVAVGWFGGNCNKCIPCRRGLFMQCVNMQVPSWHYPGGYAESVVVPATAPARIPDGLSFVEAAPMGCAGVTTFNGLRQ
TRARAGDLVAVLGIGGLGHLGVQFARAMGFETVAIARGAAKEDDARALGAHHYIDSTAGDVAAALQKLGGAAVVLATAAS
SAAMGQTVGGLGPQGELIVVGVTPEQLPISPLDLINSGLSVTGHPSGTARDVEETMHFAVLSGVRARVEEKPLAEAAEAY
AAMDEGRARYRMVLTM

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565152, Length=380, Percent_Identity=26.3157894736842, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI34577061, Length=235, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4501933, Length=226, Percent_Identity=26.9911504424779, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI156523966, Length=323, Percent_Identity=25.6965944272446, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI262073058, Length=255, Percent_Identity=25.0980392156863, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4501939, Length=323, Percent_Identity=25.6965944272446, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI71743840, Length=255, Percent_Identity=25.0980392156863, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4501929, Length=226, Percent_Identity=26.9911504424779, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI71565154, Length=198, Percent_Identity=28.2828282828283, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081918, Length=313, Percent_Identity=34.5047923322684, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786518, Length=342, Percent_Identity=34.2105263157895, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI87082401, Length=337, Percent_Identity=29.080118694362, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788075, Length=290, Percent_Identity=29.3103448275862, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787863, Length=272, Percent_Identity=26.8382352941176, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788073, Length=277, Percent_Identity=28.5198555956679, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788407, Length=253, Percent_Identity=28.4584980237154, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082125, Length=331, Percent_Identity=25.0755287009063, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790045, Length=291, Percent_Identity=27.4914089347079, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI226510992, Length=328, Percent_Identity=26.219512195122, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786552, Length=302, Percent_Identity=29.4701986754967, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=340, Percent_Identity=30, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71988145, Length=338, Percent_Identity=27.5147928994083, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17562582, Length=340, Percent_Identity=27.6470588235294, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17562876, Length=266, Percent_Identity=29.6992481203008, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=209, Percent_Identity=31.1004784688995, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25146526, Length=236, Percent_Identity=25.8474576271186, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323961, Length=341, Percent_Identity=31.0850439882698, Blast_Score=152, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323729, Length=341, Percent_Identity=29.9120234604106, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=29.585798816568, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324486, Length=339, Percent_Identity=29.7935103244838, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319949, Length=334, Percent_Identity=27.8443113772455, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323980, Length=337, Percent_Identity=27.5964391691395, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319257, Length=302, Percent_Identity=25.4966887417219, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320033, Length=302, Percent_Identity=25.4966887417219, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=250, Percent_Identity=27.6, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=250, Percent_Identity=27.6, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17737895, Length=200, Percent_Identity=30, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17137530, Length=229, Percent_Identity=30.1310043668122, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737897, Length=222, Percent_Identity=30.6306306306306, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 34493; Mature: 34361

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATHKAVHVAAAGEPLTLADVETPSPPPGHLRIDVAACGVCGTDHGFVNGNFPGLSWPIT
CCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCEECCCCCCCCCCEE
LGHEIAGTVAELGDGVDEFAVGDRVAVGWFGGNCNKCIPCRRGLFMQCVNMQVPSWHYPG
ECHHHHHHHHHHCCCHHHHHCCCEEEEEEECCCCCCCCHHHCCHHHHHHCCCCCCEECCC
GYAESVVVPATAPARIPDGLSFVEAAPMGCAGVTTFNGLRQTRARAGDLVAVLGIGGLGH
CCCCCEEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHH
LGVQFARAMGFETVAIARGAAKEDDARALGAHHYIDSTAGDVAAALQKLGGAAVVLATAA
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECC
SSAAMGQTVGGLGPQGELIVVGVTPEQLPISPLDLINSGLSVTGHPSGTARDVEETMHFA
CHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHH
VLSGVRARVEEKPLAEAAEAYAAMDEGRARYRMVLTM
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure 
ATHKAVHVAAAGEPLTLADVETPSPPPGHLRIDVAACGVCGTDHGFVNGNFPGLSWPIT
CCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCEECCCCCCCCCCEE
LGHEIAGTVAELGDGVDEFAVGDRVAVGWFGGNCNKCIPCRRGLFMQCVNMQVPSWHYPG
ECHHHHHHHHHHCCCHHHHHCCCEEEEEEECCCCCCCCHHHCCHHHHHHCCCCCCEECCC
GYAESVVVPATAPARIPDGLSFVEAAPMGCAGVTTFNGLRQTRARAGDLVAVLGIGGLGH
CCCCCEEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHH
LGVQFARAMGFETVAIARGAAKEDDARALGAHHYIDSTAGDVAAALQKLGGAAVVLATAA
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECC
SSAAMGQTVGGLGPQGELIVVGVTPEQLPISPLDLINSGLSVTGHPSGTARDVEETMHFA
CHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHH
VLSGVRARVEEKPLAEAAEAYAAMDEGRARYRMVLTM
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]