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The map label for this gene is nfxB [H]

Identifier: 108797464

GI number: 108797464

Start: 539000

End: 539560

Strand: Reverse

Name: nfxB [H]

Synonym: Mmcs_0484

Alternate gene names: 108797464

Gene position: 539560-539000 (Counterclockwise)

Preceding gene: 108797467

Following gene: 108797463

Centisome position: 9.46

GC content: 70.59

Gene sequence:

>561_bases
ATGAGATACTCTCGCTTCATGGTGACCGACCGCGAGTCTGTGCTGCGCGCCGCCGCGGACTTCCTGGGCCGCCGGCCGAA
CGCGACCCAGGACGAGATCGCGGCCGCCGTCGGCGTCAGCAGGGCGACGCTGCACCGCCACTTCGCCGGGAAACCGGCGT
TGATGGCCGCACTCGACGACCTCGCGATCGCCGAGATGCGTACCGCGGTCGACGCGGCACGCCTGTCGGAGGGTTCGGCG
GCCGACGCGCTGCGCCGCCTGGTCGCCGCCTGCCGACCGGTGTCGCCGTATCTGGCGCTGCTCTACAGCCAGAGCCAGGA
CATCGACGGCGACCAGTCCATGCAGGGCTGGGCGGAATCCGACGCCGCGATCACCGCGCTGTTCGAACGGGGCCAGCGCT
CCGGGGAGTTCCGTCCCGACCTGACCGCGGCGTGGCTGACCGAGGCGCTCTACAGCCTGGTCGCCGGCGCGGGCTGGTGT
ATCCAGGTCGGCCGCGCGGCCGGCCGCGACTTCGAACGCATGATCTCCGAACTACTGCTGAGTGGAGTGCAGAACTCATG
A

Upstream 100 bases:

>100_bases
CGCCCGGTTTGCCCACAGCTGATCCATGGGTCGATCCTGCCTTACCGGCCCCGCCGCGGGAACCGCTCCGGCCAACAGCG
ATGAGACAAATCTGTCTCAG

Downstream 100 bases:

>100_bases
CCCGCCGCTGGCTCGCCCTGAGCGTGCTCACCCTGGCGGTCCTCGTCATCGGCATCGACGGCACCGTGCTGGCGCTGGCG
ACACCGTTCATCAGCAGCGA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MRYSRFMVTDRESVLRAAADFLGRRPNATQDEIAAAVGVSRATLHRHFAGKPALMAALDDLAIAEMRTAVDAARLSEGSA
ADALRRLVAACRPVSPYLALLYSQSQDIDGDQSMQGWAESDAAITALFERGQRSGEFRPDLTAAWLTEALYSLVAGAGWC
IQVGRAAGRDFERMISELLLSGVQNS

Sequences:

>Translated_186_residues
MRYSRFMVTDRESVLRAAADFLGRRPNATQDEIAAAVGVSRATLHRHFAGKPALMAALDDLAIAEMRTAVDAARLSEGSA
ADALRRLVAACRPVSPYLALLYSQSQDIDGDQSMQGWAESDAAITALFERGQRSGEFRPDLTAAWLTEALYSLVAGAGWC
IQVGRAAGRDFERMISELLLSGVQNS
>Mature_186_residues
MRYSRFMVTDRESVLRAAADFLGRRPNATQDEIAAAVGVSRATLHRHFAGKPALMAALDDLAIAEMRTAVDAARLSEGSA
ADALRRLVAACRPVSPYLALLYSQSQDIDGDQSMQGWAESDAAITALFERGQRSGEFRPDLTAAWLTEALYSLVAGAGWC
IQVGRAAGRDFERMISELLLSGVQNS

Specific function: Confers resistance to guinolones. May negatively regulate the expression of genes that are associated with cell permeability to drugs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR000843
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR005471 [H]

Pfam domain/function: PF09339 HTH_IclR [H]

EC number: NA

Molecular weight: Translated: 20108; Mature: 20108

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYSRFMVTDRESVLRAAADFLGRRPNATQDEIAAAVGVSRATLHRHFAGKPALMAALDD
CCCCCCEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LAIAEMRTAVDAARLSEGSAADALRRLVAACRPVSPYLALLYSQSQDIDGDQSMQGWAES
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
DAAITALFERGQRSGEFRPDLTAAWLTEALYSLVAGAGWCIQVGRAAGRDFERMISELLL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
SGVQNS
HHCCCC
>Mature Secondary Structure
MRYSRFMVTDRESVLRAAADFLGRRPNATQDEIAAAVGVSRATLHRHFAGKPALMAALDD
CCCCCCEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LAIAEMRTAVDAARLSEGSAADALRRLVAACRPVSPYLALLYSQSQDIDGDQSMQGWAES
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
DAAITALFERGQRSGEFRPDLTAAWLTEALYSLVAGAGWCIQVGRAAGRDFERMISELLL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
SGVQNS
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1330820; 10984043 [H]