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The map label for this gene is pimE [H]

Identifier: 108797448

GI number: 108797448

Start: 522719

End: 523987

Strand: Direct

Name: pimE [H]

Synonym: Mmcs_0468

Alternate gene names: 108797448

Gene position: 522719-523987 (Clockwise)

Preceding gene: 108797447

Following gene: 108797452

Centisome position: 9.16

GC content: 67.38

Gene sequence:

>1269_bases
GTGCCTGAGTCGGGAGTGCCGGCCGGGCGCCGGCGACTTCTGGCCCCGCTGTTGCTGGTCACCAGCGCCGCGGCGCTGCT
TGCCGTGACCATGGCCAATCCGCCCGATCTCGTCGACTTCCACGTGTACATGCTTGGTGGTGTCGCTTTGGACCGGCCGG
ACACCCTGTACTCCTTCGCCTACTCCGATCAATCGCCGGACCAACCTCTTCCGTTCGTCTACCCACCCTTCGCGGCGATA
CTGTTCCGTCCACTGACCGCGCTGCCCTTCGTCGTGGCCGGGGTGTTGTGGCAACTTGGCATTCTGGCCGCGGTGTACGG
GATCGTCCGGATCAGTCAGCGCCTGCTGGGCGGCGGCAGTCACCGCACCGCCATGTTGTGGACCGCGGGCCTGATCTGGC
TCGAACCGGTGCGAGTCGCGCTGGATCTCGGGCAGGTCGGCATCTTCCTGACTTTGGCCGTGCTCTACGCGGTCTGCAGC
AGGCGCTGGTGGTTGTCGGGATTGTTGGTCGGGCTCGCGGCCGGGGTGAAGCTGACCCCGGCGATCACCGGCCTCTACTT
CCTCGGGGTGCGGCGCTGGACCGCCGCCGCCTTCTCGGCGGTCGTCTTCGTCGCCACCATCGGGCTGTCCTATCTCGTCG
TAGGCGACCAGGTACGGAACTACTTCACCCGGGTGATGGGCGACACCAGCATCAATCCGATCGGCATCGCCTTAAACCAG
TCCTGGCGGGGCGCAATCTCCAGGTTTCTGGGCCATGACGCGGGTGGGAGCGCGCTGGTTATCGCCGCGATCGCGGGAAC
GGCAGTGCTGGCGCTGTTCGCATGGGCCGCGCTGGGGGCGGGCTCCCGCCCTCGAGATCGCCTGGGTTCGGTGCTCGTCG
TCCAGCTCTTCGGCTTGTTGATGTCACCGATCTCGTGGGTCCACCACTGGGCCTGGGTGGTTCCGCTCGTGCTCTGGCTA
CTCAGCGGACCCTGGCGCAACGAGCCGGGCGCCCGCGTCCTCGGTTGGGGATGGCTGGCCTTGACCTTCGTGGGTGTTCC
CAGCCAGCTCTCCCTCTTGGAGCCGAGTCTGTGGGAGATCAGCCGGCCGTGGTATCTGGCATGGGCGGGGCTGGCGTATG
TCGTTGCCGCGGTGGCGACACTCGGGTGGATCGTTCTGACCGGTCGGCGAAATGCCGCGCCGACGCCTCCGGTTCGGCGA
AGATTCGCCCGTGTAGTCGGCACGCGGGGGAAGCAGATCGCTTGCGAGGAGCACCGCGCGGGCCGCTAG

Upstream 100 bases:

>100_bases
ATCTGGGAGATCAGCCGGCCCTGGTACCTTGCGTGGGCTGAAATGGTCTACATCGTCGCGTCGTTGTCGACGCTGGCCTG
GATCATCAGAACCGGGCGCC

Downstream 100 bases:

>100_bases
GTCACCCTGATGGTGAACCGACTCGTATCGGGTTCACCCGGCGCCGCCACCCGGTAGTTCTCGCGGCGCAGCGCGTCGGT
GGGCGCGGCCATCGGTTCGA

Product: mannosyltransferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MPESGVPAGRRRLLAPLLLVTSAAALLAVTMANPPDLVDFHVYMLGGVALDRPDTLYSFAYSDQSPDQPLPFVYPPFAAI
LFRPLTALPFVVAGVLWQLGILAAVYGIVRISQRLLGGGSHRTAMLWTAGLIWLEPVRVALDLGQVGIFLTLAVLYAVCS
RRWWLSGLLVGLAAGVKLTPAITGLYFLGVRRWTAAAFSAVVFVATIGLSYLVVGDQVRNYFTRVMGDTSINPIGIALNQ
SWRGAISRFLGHDAGGSALVIAAIAGTAVLALFAWAALGAGSRPRDRLGSVLVVQLFGLLMSPISWVHHWAWVVPLVLWL
LSGPWRNEPGARVLGWGWLALTFVGVPSQLSLLEPSLWEISRPWYLAWAGLAYVVAAVATLGWIVLTGRRNAAPTPPVRR
RFARVVGTRGKQIACEEHRAGR

Sequences:

>Translated_422_residues
MPESGVPAGRRRLLAPLLLVTSAAALLAVTMANPPDLVDFHVYMLGGVALDRPDTLYSFAYSDQSPDQPLPFVYPPFAAI
LFRPLTALPFVVAGVLWQLGILAAVYGIVRISQRLLGGGSHRTAMLWTAGLIWLEPVRVALDLGQVGIFLTLAVLYAVCS
RRWWLSGLLVGLAAGVKLTPAITGLYFLGVRRWTAAAFSAVVFVATIGLSYLVVGDQVRNYFTRVMGDTSINPIGIALNQ
SWRGAISRFLGHDAGGSALVIAAIAGTAVLALFAWAALGAGSRPRDRLGSVLVVQLFGLLMSPISWVHHWAWVVPLVLWL
LSGPWRNEPGARVLGWGWLALTFVGVPSQLSLLEPSLWEISRPWYLAWAGLAYVVAAVATLGWIVLTGRRNAAPTPPVRR
RFARVVGTRGKQIACEEHRAGR
>Mature_421_residues
PESGVPAGRRRLLAPLLLVTSAAALLAVTMANPPDLVDFHVYMLGGVALDRPDTLYSFAYSDQSPDQPLPFVYPPFAAIL
FRPLTALPFVVAGVLWQLGILAAVYGIVRISQRLLGGGSHRTAMLWTAGLIWLEPVRVALDLGQVGIFLTLAVLYAVCSR
RWWLSGLLVGLAAGVKLTPAITGLYFLGVRRWTAAAFSAVVFVATIGLSYLVVGDQVRNYFTRVMGDTSINPIGIALNQS
WRGAISRFLGHDAGGSALVIAAIAGTAVLALFAWAALGAGSRPRDRLGSVLVVQLFGLLMSPISWVHHWAWVVPLVLWLL
SGPWRNEPGARVLGWGWLALTFVGVPSQLSLLEPSLWEISRPWYLAWAGLAYVVAAVATLGWIVLTGRRNAAPTPPVRRR
FARVVGTRGKQIACEEHRAGR

Specific function: Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol pentamannoside (AcPIM5) to generate a monoacyl phosphatidylinositol hexamannoside (AcPIM6) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PIGM family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 45577; Mature: 45446

Theoretical pI: Translated: 11.18; Mature: 11.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESGVPAGRRRLLAPLLLVTSAAALLAVTMANPPDLVDFHVYMLGGVALDRPDTLYSFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEECCCCHHHEEE
YSDQSPDQPLPFVYPPFAAILFRPLTALPFVVAGVLWQLGILAAVYGIVRISQRLLGGGS
ECCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HRTAMLWTAGLIWLEPVRVALDLGQVGIFLTLAVLYAVCSRRWWLSGLLVGLAAGVKLTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECH
AITGLYFLGVRRWTAAAFSAVVFVATIGLSYLVVGDQVRNYFTRVMGDTSINPIGIALNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHCCCCCCCEEEEECC
SWRGAISRFLGHDAGGSALVIAAIAGTAVLALFAWAALGAGSRPRDRLGSVLVVQLFGLL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
MSPISWVHHWAWVVPLVLWLLSGPWRNEPGARVLGWGWLALTFVGVPSQLSLLEPSLWEI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHCCCHHHHC
SRPWYLAWAGLAYVVAAVATLGWIVLTGRRNAAPTPPVRRRFARVVGTRGKQIACEEHRA
CCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEHHCCC
GR
CC
>Mature Secondary Structure 
PESGVPAGRRRLLAPLLLVTSAAALLAVTMANPPDLVDFHVYMLGGVALDRPDTLYSFA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEECCCCHHHEEE
YSDQSPDQPLPFVYPPFAAILFRPLTALPFVVAGVLWQLGILAAVYGIVRISQRLLGGGS
ECCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HRTAMLWTAGLIWLEPVRVALDLGQVGIFLTLAVLYAVCSRRWWLSGLLVGLAAGVKLTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECH
AITGLYFLGVRRWTAAAFSAVVFVATIGLSYLVVGDQVRNYFTRVMGDTSINPIGIALNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHCCCCCCCEEEEECC
SWRGAISRFLGHDAGGSALVIAAIAGTAVLALFAWAALGAGSRPRDRLGSVLVVQLFGLL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
MSPISWVHHWAWVVPLVLWLLSGPWRNEPGARVLGWGWLALTFVGVPSQLSLLEPSLWEI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHCCCHHHHC
SRPWYLAWAGLAYVVAAVATLGWIVLTGRRNAAPTPPVRRRFARVVGTRGKQIACEEHRA
CCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEHHCCC
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]