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The map label for this gene is aspC [H]

Identifier: 108797421

GI number: 108797421

Start: 488890

End: 490176

Strand: Reverse

Name: aspC [H]

Synonym: Mmcs_0441

Alternate gene names: 108797421

Gene position: 490176-488890 (Counterclockwise)

Preceding gene: 108797422

Following gene: 108797420

Centisome position: 8.59

GC content: 66.43

Gene sequence:

>1287_bases
ATGGACGACGTGACCATGCCTCAGACGCCGGCCGAGCGGACCTGGCACCCCCAGGGCCACCAGCCGCGGCCCCGTACGTT
CACGCAGTCGTCGAAGCTGCAGGACGTCCTCTACGAGATCCGCGGCCCGGTACACGAGCACGCGTCGCGGCTGGAGGCCG
AGGGCCACCGCATCCTCAAGCTCAACATCGGCAACCCGGCGCCGTTCGGCTTCGAGGCACCCGATGTGATCATGCGCGAC
ATCATCCAGGCGCTGCCGTACGCGCAGGGCTACTCGGACTCCAAGGGCATCATGCCCGCGCGCCGGGCGGTGTTCACCCG
CTACGAACTCGTCGACGGGTTCCCGCGCTTCGACGTCGACGACGTGTTCCTCGGCAACGGGGCCTCCGAGCTCATCCAGA
TGGTGCTGCAGGCACTGCTGGACAACGGCGATCAGGTGCTGATCCCGGCGCCGGACTATCCGCTGTGGACGGCGTGCACC
TCGCTGGCGGGCGGCACCCCGGTGCACTACCTGTGTGACGAGACGCAGGGCTGGAATCCCGACGTCGCCGACATCGAGTC
GAAGATCACCGACCGCACCAAGGCGATCGTCGTCATCAACCCGAACAACCCGACCGGCGCGGTGTACAGCCGCGAGACGC
TGGAGCGGATCGCCGATCTCGCCCGGAAACACCAGCTGCTGCTGCTGGCCGACGAGATCTACGACAAGATCCTCTACGAC
GATGCCAAGCACATCTCGCTGGCCTCGGTCGCGCCCGACGTGTTGACCCTGACGTTCAACGGGCTGTCGAAGGCCTACCG
GGTGGCGGGTTACCGCTCGGGCTGGCTGGTGATCACCGGACCCAAGGAGCACGCCAGCAGCTTCATCGAGGGCATCAGCC
TGCTGGCCAACATGCGGTTGTGCCCGAATGTGCCTGCACAGCATGCGATTCAGGTGGCGCTCGGCGGCCATCAGAGCATC
GACGATCTGGTGTTGCCCGGCGGGCGGTTGCTCGAGCAGCGCGACGTGGCCTGGGAGAAGCTCAACGAGATTCCCGGCGT
CTCGTGCGTGAAGCCGGCCGGCGCGCTGTACGCGTTCCCGCGGCTGGATCCCGAGGTCTACGAGATCCACGACGACGAGC
TGCTGGTGCTCGACCTGCTGCTGCAGGAAAAAATCCTGGTTGTGCAGGGCACCGGGTTCAACTGGCCGACACCGGATCAC
CTGCGCATCGTCACGCTGCCGTGGGCTCGTGACCTGGCCAACGCCATCGAGCGTCTCGGCAACTTCCTGGTCAGCTACCG
GCAGTAG

Upstream 100 bases:

>100_bases
CGGCCGGGGAAGCGCTGACCCCGCACGCACCGCGGTGGCGGCGGGCCTGCCCGGCCGCCGACCTGCACGAATTTCTAATT
GAGTGGACGGCAATGCCACC

Downstream 100 bases:

>100_bases
CGAGTGTCGCACTCCCACCCGCATTCCCACTCGCTGAGCGGGCCGTCCCCGCTCGGCCCGTTGGCCGCCAGGATCGTCGT
CGGGTTGCTGGCGCTCATCG

Product: aminotransferase AlaT

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MDDVTMPQTPAERTWHPQGHQPRPRTFTQSSKLQDVLYEIRGPVHEHASRLEAEGHRILKLNIGNPAPFGFEAPDVIMRD
IIQALPYAQGYSDSKGIMPARRAVFTRYELVDGFPRFDVDDVFLGNGASELIQMVLQALLDNGDQVLIPAPDYPLWTACT
SLAGGTPVHYLCDETQGWNPDVADIESKITDRTKAIVVINPNNPTGAVYSRETLERIADLARKHQLLLLADEIYDKILYD
DAKHISLASVAPDVLTLTFNGLSKAYRVAGYRSGWLVITGPKEHASSFIEGISLLANMRLCPNVPAQHAIQVALGGHQSI
DDLVLPGGRLLEQRDVAWEKLNEIPGVSCVKPAGALYAFPRLDPEVYEIHDDELLVLDLLLQEKILVVQGTGFNWPTPDH
LRIVTLPWARDLANAIERLGNFLVSYRQ

Sequences:

>Translated_428_residues
MDDVTMPQTPAERTWHPQGHQPRPRTFTQSSKLQDVLYEIRGPVHEHASRLEAEGHRILKLNIGNPAPFGFEAPDVIMRD
IIQALPYAQGYSDSKGIMPARRAVFTRYELVDGFPRFDVDDVFLGNGASELIQMVLQALLDNGDQVLIPAPDYPLWTACT
SLAGGTPVHYLCDETQGWNPDVADIESKITDRTKAIVVINPNNPTGAVYSRETLERIADLARKHQLLLLADEIYDKILYD
DAKHISLASVAPDVLTLTFNGLSKAYRVAGYRSGWLVITGPKEHASSFIEGISLLANMRLCPNVPAQHAIQVALGGHQSI
DDLVLPGGRLLEQRDVAWEKLNEIPGVSCVKPAGALYAFPRLDPEVYEIHDDELLVLDLLLQEKILVVQGTGFNWPTPDH
LRIVTLPWARDLANAIERLGNFLVSYRQ
>Mature_428_residues
MDDVTMPQTPAERTWHPQGHQPRPRTFTQSSKLQDVLYEIRGPVHEHASRLEAEGHRILKLNIGNPAPFGFEAPDVIMRD
IIQALPYAQGYSDSKGIMPARRAVFTRYELVDGFPRFDVDDVFLGNGASELIQMVLQALLDNGDQVLIPAPDYPLWTACT
SLAGGTPVHYLCDETQGWNPDVADIESKITDRTKAIVVINPNNPTGAVYSRETLERIADLARKHQLLLLADEIYDKILYD
DAKHISLASVAPDVLTLTFNGLSKAYRVAGYRSGWLVITGPKEHASSFIEGISLLANMRLCPNVPAQHAIQVALGGHQSI
DDLVLPGGRLLEQRDVAWEKLNEIPGVSCVKPAGALYAFPRLDPEVYEIHDDELLVLDLLLQEKILVVQGTGFNWPTPDH
LRIVTLPWARDLANAIERLGNFLVSYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=480, Percent_Identity=26.4583333333333, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI215599424, Length=373, Percent_Identity=28.686327077748, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI4507369, Length=374, Percent_Identity=27.2727272727273, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI4885351, Length=436, Percent_Identity=28.8990825688073, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI95147551, Length=240, Percent_Identity=29.5833333333333, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI169881279, Length=240, Percent_Identity=29.5833333333333, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI56713254, Length=172, Percent_Identity=33.1395348837209, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI56713256, Length=172, Percent_Identity=33.1395348837209, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI169881281, Length=144, Percent_Identity=34.7222222222222, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI149944424, Length=313, Percent_Identity=25.8785942492013, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1788627, Length=400, Percent_Identity=62, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI1788722, Length=397, Percent_Identity=28.2115869017632, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786816, Length=295, Percent_Identity=23.728813559322, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=29.6296296296296, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71981209, Length=459, Percent_Identity=25.2723311546841, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=205, Percent_Identity=32.6829268292683, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=205, Percent_Identity=32.6829268292683, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=27.5510204081633, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=204, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320317, Length=471, Percent_Identity=25.9023354564756, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6323118, Length=453, Percent_Identity=26.2693156732892, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=238, Percent_Identity=26.4705882352941, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=28.9124668435013, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24641770, Length=468, Percent_Identity=27.5641025641026, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24641760, Length=468, Percent_Identity=27.5641025641026, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24641768, Length=468, Percent_Identity=27.5641025641026, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24641766, Length=468, Percent_Identity=27.5641025641026, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24641764, Length=468, Percent_Identity=27.5641025641026, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI45551451, Length=468, Percent_Identity=27.5641025641026, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28573069, Length=263, Percent_Identity=28.8973384030418, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646114, Length=263, Percent_Identity=28.8973384030418, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573067, Length=263, Percent_Identity=28.8973384030418, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573065, Length=263, Percent_Identity=28.8973384030418, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 47596; Mature: 47596

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDVTMPQTPAERTWHPQGHQPRPRTFTQSSKLQDVLYEIRGPVHEHASRLEAEGHRILK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEE
LNIGNPAPFGFEAPDVIMRDIIQALPYAQGYSDSKGIMPARRAVFTRYELVDGFPRFDVD
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
DVFLGNGASELIQMVLQALLDNGDQVLIPAPDYPLWTACTSLAGGTPVHYLCDETQGWNP
CEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
DVADIESKITDRTKAIVVINPNNPTGAVYSRETLERIADLARKHQLLLLADEIYDKILYD
CHHHHHHHHCCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHCCEEEEHHHHHHHHHHC
DAKHISLASVAPDVLTLTFNGLSKAYRVAGYRSGWLVITGPKEHASSFIEGISLLANMRL
CCCCEEHHHCCCCEEEEEEHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCC
CPNVPAQHAIQVALGGHQSIDDLVLPGGRLLEQRDVAWEKLNEIPGVSCVKPAGALYAFP
CCCCCHHHEEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCEEECC
RLDPEVYEIHDDELLVLDLLLQEKILVVQGTGFNWPTPDHLRIVTLPWARDLANAIERLG
CCCCCEEEECCCCCHHHHHHHHCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHH
NFLVSYRQ
HHHHHCCC
>Mature Secondary Structure
MDDVTMPQTPAERTWHPQGHQPRPRTFTQSSKLQDVLYEIRGPVHEHASRLEAEGHRILK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEE
LNIGNPAPFGFEAPDVIMRDIIQALPYAQGYSDSKGIMPARRAVFTRYELVDGFPRFDVD
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
DVFLGNGASELIQMVLQALLDNGDQVLIPAPDYPLWTACTSLAGGTPVHYLCDETQGWNP
CEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
DVADIESKITDRTKAIVVINPNNPTGAVYSRETLERIADLARKHQLLLLADEIYDKILYD
CHHHHHHHHCCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHCCEEEEHHHHHHHHHHC
DAKHISLASVAPDVLTLTFNGLSKAYRVAGYRSGWLVITGPKEHASSFIEGISLLANMRL
CCCCEEHHHCCCCEEEEEEHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCC
CPNVPAQHAIQVALGGHQSIDDLVLPGGRLLEQRDVAWEKLNEIPGVSCVKPAGALYAFP
CCCCCHHHEEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCEEECC
RLDPEVYEIHDDELLVLDLLLQEKILVVQGTGFNWPTPDHLRIVTLPWARDLANAIERLG
CCCCCEEEECCCCCHHHHHHHHCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHH
NFLVSYRQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]