The gene/protein map for NC_008146 is currently unavailable.
Definition Mycobacterium sp. MCS chromosome, complete genome.
Accession NC_008146
Length 5,705,448

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The map label for this gene is ucpA [C]

Identifier: 108797302

GI number: 108797302

Start: 360878

End: 361717

Strand: Direct

Name: ucpA [C]

Synonym: Mmcs_0322

Alternate gene names: 108797302

Gene position: 360878-361717 (Clockwise)

Preceding gene: 108797301

Following gene: 108797305

Centisome position: 6.33

GC content: 68.81

Gene sequence:

>840_bases
ATGACAGTGGGACGTCTGGCCGGCAAGGTGGCGCTGATCACCGGAGCGGCACGCGGCATCGGCCGAGCGCAGGCCGTGCG
CTTCGCGCAAGAGGGGGCGGACATCATCGCCCTGGACATCTGCGGGCCCGTCGACGACACCGTGGTGGTTCCTTCTGCGA
CCCGGCGGGACCTCGACGAGACCGCTTGCCTGGTCGCCGAGGTCGGCGTCCGCGTCGTCACCGAGGTCGTCGACGTGCGC
GACCCCGATGCGCTGCAAGCGGCCACCGACGCGGCGGTGACGGATCTGGGTGGTATCGACATCGTGTGCGCCACCGCAGG
CATCACCTCCAGGGGTGCGGCGACGCAGATGCCGGAGGACACCTGGCAGACCATGCTCGATGTGAACCTCACCGGTGTCT
GGCACACGTGCAAGGTGTCCGCCCCGCACCTGATCGCGCGGGGCGCCGGATCGGTGATCCTGGTCAGTTCGATCGCCGGC
CTGCGCGGGCTGGTCGGCGTTGCCCACTACACCGCGGCCAAACACGGTGTGGTCGGCCTCATGCGCAGCCTCGCCCACGA
CCTGGCACCGCACGGCATTCGCGTCAACTCCGTGCATCCGACGAACGTCGACACACCATTGATCCAGAACACGGCCGTCA
GCAGCGCTTTCCGCCCAGACCTGGACCGTCCACCTACAAGGGCGGAGTTCGCGGCGGCCGCGAGGCCGATGAACCTGCTC
GCGATCCCCTGGATCGACCCCGTCGACGTGGCCAACGCCTCGCTGTTCCTGGCGTCCGACGAAGCTCGCTACATCACGGC
GGTGTCGCTACCCGTTGACGCGGGCAGCACGCAACGCTGA

Upstream 100 bases:

>100_bases
CGGTCGACGTCGCCAACGCGGTGGTGTTCCTCGCCTCAGACGAGGCGCGCTACATCACCGGCTCACAGCTCGTCGTCGAC
GCGGGCCTGACGCAGAAGGT

Downstream 100 bases:

>100_bases
GAGCGTCACTCTCGCAACAGGAATGACAATACCGCGGCTTCGAACGCCGCCTTGGCCTCGATCATCGCCCAGTGTCCGCA
GTTCGGGAACACGTGCAGCT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTVGRLAGKVALITGAARGIGRAQAVRFAQEGADIIALDICGPVDDTVVVPSATRRDLDETACLVAEVGVRVVTEVVDVR
DPDALQAATDAAVTDLGGIDIVCATAGITSRGAATQMPEDTWQTMLDVNLTGVWHTCKVSAPHLIARGAGSVILVSSIAG
LRGLVGVAHYTAAKHGVVGLMRSLAHDLAPHGIRVNSVHPTNVDTPLIQNTAVSSAFRPDLDRPPTRAEFAAAARPMNLL
AIPWIDPVDVANASLFLASDEARYITAVSLPVDAGSTQR

Sequences:

>Translated_279_residues
MTVGRLAGKVALITGAARGIGRAQAVRFAQEGADIIALDICGPVDDTVVVPSATRRDLDETACLVAEVGVRVVTEVVDVR
DPDALQAATDAAVTDLGGIDIVCATAGITSRGAATQMPEDTWQTMLDVNLTGVWHTCKVSAPHLIARGAGSVILVSSIAG
LRGLVGVAHYTAAKHGVVGLMRSLAHDLAPHGIRVNSVHPTNVDTPLIQNTAVSSAFRPDLDRPPTRAEFAAAARPMNLL
AIPWIDPVDVANASLFLASDEARYITAVSLPVDAGSTQR
>Mature_278_residues
TVGRLAGKVALITGAARGIGRAQAVRFAQEGADIIALDICGPVDDTVVVPSATRRDLDETACLVAEVGVRVVTEVVDVRD
PDALQAATDAAVTDLGGIDIVCATAGITSRGAATQMPEDTWQTMLDVNLTGVWHTCKVSAPHLIARGAGSVILVSSIAGL
RGLVGVAHYTAAKHGVVGLMRSLAHDLAPHGIRVNSVHPTNVDTPLIQNTAVSSAFRPDLDRPPTRAEFAAAARPMNLLA
IPWIDPVDVANASLFLASDEARYITAVSLPVDAGSTQR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=282, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI32483357, Length=275, Percent_Identity=31.6363636363636, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI66933014, Length=278, Percent_Identity=29.136690647482, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI126723750, Length=278, Percent_Identity=27.6978417266187, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=28.9340101522843, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=267, Percent_Identity=28.0898876404494, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI7705925, Length=272, Percent_Identity=30.5147058823529, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI5031737, Length=276, Percent_Identity=28.9855072463768, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI59889578, Length=205, Percent_Identity=30.7317073170732, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI10190704, Length=268, Percent_Identity=27.2388059701493, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI33667109, Length=203, Percent_Identity=32.0197044334975, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI25282469, Length=241, Percent_Identity=26.1410788381743, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI40807363, Length=207, Percent_Identity=27.536231884058, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=29.4685990338164, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4758504, Length=214, Percent_Identity=31.7757009345794, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI210032110, Length=208, Percent_Identity=25.4807692307692, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI142976729, Length=212, Percent_Identity=27.8301886792453, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254986, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI19923817, Length=284, Percent_Identity=26.7605633802817, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=208, Percent_Identity=25.9615384615385, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503817, Length=202, Percent_Identity=24.2574257425743, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI223718074, Length=211, Percent_Identity=30.8056872037915, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=37.6146788990826, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI83715985, Length=199, Percent_Identity=30.6532663316583, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI224922801, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=36.231884057971, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1789208, Length=275, Percent_Identity=30.9090909090909, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787335, Length=270, Percent_Identity=30.7407407407407, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790717, Length=271, Percent_Identity=30.9963099630996, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787905, Length=278, Percent_Identity=28.0575539568345, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082160, Length=279, Percent_Identity=26.8817204301075, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1786812, Length=272, Percent_Identity=27.9411764705882, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788459, Length=268, Percent_Identity=27.2388059701493, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789378, Length=265, Percent_Identity=27.5471698113208, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367365, Length=204, Percent_Identity=31.8627450980392, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789057, Length=184, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788891, Length=186, Percent_Identity=31.7204301075269, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=26.5625, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=272, Percent_Identity=29.0441176470588, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17555706, Length=271, Percent_Identity=29.8892988929889, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=277, Percent_Identity=28.158844765343, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=283, Percent_Identity=30.3886925795053, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17568967, Length=224, Percent_Identity=29.9107142857143, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=280, Percent_Identity=29.6428571428571, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=275, Percent_Identity=26.9090909090909, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=290, Percent_Identity=31.3793103448276, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=205, Percent_Identity=27.8048780487805, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=283, Percent_Identity=30.0353356890459, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=276, Percent_Identity=30.0724637681159, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=284, Percent_Identity=29.9295774647887, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=210, Percent_Identity=26.1904761904762, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=283, Percent_Identity=30.3886925795053, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=216, Percent_Identity=28.2407407407407, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=207, Percent_Identity=26.5700483091787, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=285, Percent_Identity=29.8245614035088, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=285, Percent_Identity=29.1228070175439, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=289, Percent_Identity=28.3737024221453, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=288, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=289, Percent_Identity=29.757785467128, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=286, Percent_Identity=29.7202797202797, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=287, Percent_Identity=27.1777003484321, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71982365, Length=207, Percent_Identity=27.536231884058, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=288, Percent_Identity=27.4305555555556, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=283, Percent_Identity=29.3286219081272, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=216, Percent_Identity=26.8518518518519, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=204, Percent_Identity=26.4705882352941, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=290, Percent_Identity=28.9655172413793, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=272, Percent_Identity=29.0441176470588, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=209, Percent_Identity=31.1004784688995, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=285, Percent_Identity=29.4736842105263, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17558628, Length=201, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324126, Length=272, Percent_Identity=25.7352941176471, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=271, Percent_Identity=31.3653136531365, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24639444, Length=279, Percent_Identity=31.1827956989247, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21355319, Length=279, Percent_Identity=28.3154121863799, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI23397609, Length=272, Percent_Identity=33.4558823529412, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21357041, Length=268, Percent_Identity=31.7164179104478, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571526, Length=268, Percent_Identity=29.8507462686567, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=29.9492385786802, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281364892, Length=213, Percent_Identity=30.0469483568075, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640492, Length=207, Percent_Identity=25.6038647342995, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17737361, Length=211, Percent_Identity=27.9620853080569, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357673, Length=203, Percent_Identity=29.5566502463054, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21355631, Length=184, Percent_Identity=29.8913043478261, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581726, Length=220, Percent_Identity=26.8181818181818, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=202, Percent_Identity=32.6732673267327, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644337, Length=275, Percent_Identity=28, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24649181, Length=205, Percent_Identity=29.7560975609756, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007236, Length=264, Percent_Identity=26.5151515151515, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28956; Mature: 28825

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTVGRLAGKVALITGAARGIGRAQAVRFAQEGADIIALDICGPVDDTVVVPSATRRDLDE
CCCHHHHCEEEEEECCHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCEECCCHHHCCHHH
TACLVAEVGVRVVTEVVDVRDPDALQAATDAAVTDLGGIDIVCATAGITSRGAATQMPED
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHH
TWQTMLDVNLTGVWHTCKVSAPHLIARGAGSVILVSSIAGLRGLVGVAHYTAAKHGVVGL
HHHHHHEEEEEEEEEEEECCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
MRSLAHDLAPHGIRVNSVHPTNVDTPLIQNTAVSSAFRPDLDRPPTRAEFAAAARPMNLL
HHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEE
AIPWIDPVDVANASLFLASDEARYITAVSLPVDAGSTQR
EECCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TVGRLAGKVALITGAARGIGRAQAVRFAQEGADIIALDICGPVDDTVVVPSATRRDLDE
CCHHHHCEEEEEECCHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCEECCCHHHCCHHH
TACLVAEVGVRVVTEVVDVRDPDALQAATDAAVTDLGGIDIVCATAGITSRGAATQMPED
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHH
TWQTMLDVNLTGVWHTCKVSAPHLIARGAGSVILVSSIAGLRGLVGVAHYTAAKHGVVGL
HHHHHHEEEEEEEEEEEECCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
MRSLAHDLAPHGIRVNSVHPTNVDTPLIQNTAVSSAFRPDLDRPPTRAEFAAAARPMNLL
HHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEE
AIPWIDPVDVANASLFLASDEARYITAVSLPVDAGSTQR
EECCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA