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The map label for this gene is eccB1 [H]

Identifier: 108797046

GI number: 108797046

Start: 75991

End: 77466

Strand: Direct

Name: eccB1 [H]

Synonym: Mmcs_0065

Alternate gene names: 108797046

Gene position: 75991-77466 (Clockwise)

Preceding gene: 108797045

Following gene: 108797047

Centisome position: 1.33

GC content: 68.7

Gene sequence:

>1476_bases
ATGGCGAGTTTCCGGCTTACCACCAAGGTGCAGGTCAGCGGTTGGCGCTTCCTGCTGCGCCGGGTCGAGCACGCGATCGT
GCGCCGCGACACCCGGATGTTCGACGATCCGCTGCAGTTCTACAGCCGCGCGGTGGGCGCGGGCATCATCATCGCGGTGC
TGATCTGTCTCGGCGCGGCGCTGATGGCGTACTTCAAACCGCTGGGCAAGCGCGGCGGTGACCAGCTGCTCGTCGACCGC
AGCACCAACCAGCTCTATGTGGTGATGCCTGGCGGCGGGGAACTGAGGCCGGTGTACAACCTCACCTCGGCGCGGCTGGT
CCTCGGCAACCCCGGAACCCCGGTCGCGGTGAAATCCGAAGAGCTGAACCGGATGTCGAAGGGACAACCGATCGGCATCC
CCGGCGCGCCCTATGCGACGCCGGTCTCCGGTGCGGCCGAGTCGATGTGGACCCTGTGCGACACCGTCACCAAACCGGAG
AGCGTGGTCCCGAGGGTGGAGACGTCGGTCCTGGTGCGCCCGCTGGTGGTCGACTCGACCGTCGGTCCGCTGCGTCCGGA
CCAGGGCATGCTGGTGTCGTTCAAGGGTGCCAACTGGTTGGTGACCGAGGGTGGCCGACACTCGATCGACCTGGCCGACC
GTGCGGTGACGTCGGCCGTCGGGATCCCGGTGACGGCCAGGGCGACCCCGATCTCCGAGGGGCTGTTCAACGCCCTGCCG
AACGCCGGGCCATGGCAACTGCCCCAGGTGGCCCGCGCCGGTGAACCCAATACCGTTGGGCTGCCTGCGAATCTGGTGAT
CGGCTCGGTGTTCGAGACGGTGACCGAATCCGACGATCAGCAGCACTACGTCGTGCTGGCCGACGGGGTGGCCCGCGTCA
ACGACCCGACCGCCGCAGCGCTGCGCGCCACCAACTCCTACGGTCTGATCGAGCCGCCGATGGTGGAAGCCAGTGTGGTG
GCGCGGATTCCGGAGCAGGTCTACGTCTCACCGCTGCCCGACAAGGCACTCGACATCCTGCTGCGCCAGGACGATCCGAC
GCTGTGCTGGTCGTGGCAGCGCGTCGCAGGCGATCAGGCGCCCCGGACGACGGTCATCGCCGGCCGGCGACTGCCGATCG
CCGCGTCGGCGTTGAACACCGGCATCCGGCAGATCACCGGCGACTCCACCGTGTACATCGACGGCGGGCAGTTCATCCGG
TTGCAGTCACCGGATCCGCGGTACGGCGAGAGCCTCTACTACATCGACCCGCAGGGCGTGCGCTACGGCGTCTCCGACGA
GGAGACCGCCAAGAATCTCGGCCTGGTCGGACCGTTGACCGCGCCGTGGCAGGTGGTCAGCCTGCTCGTCGACGGGCCGG
TGCTGTCGAAGCAGGCCGCACTGCTCGAACACGACACCCTGCCCGCGAACCCCAACCCGCGCAAGGTCGGCGAGGACGGT
CCGGTGGCGGGCGCCCGACCGGGAGGCAGCCGATGA

Upstream 100 bases:

>100_bases
CGACAGCCTCGGGGTCGAGCAATTGAGCGAAATCAACGGCGAGGACATGGCGTCGGCGATCGCCGCCGTGCATTCCCGCC
TGAACATCAGCGGGTGAGGT

Downstream 100 bases:

>100_bases
CTGGAGTCGCTCGATGACCACGAAGAAGTTCACCCCGATCATCAAACGGGGTCCTCGGCTGACCCCAGGCGAGATCACCG
TCACCCCACCCGATGATCTG

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component B1; Type VII secretion system protein eccB1; T7SS protein eccB1 [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MASFRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRAVGAGIIIAVLICLGAALMAYFKPLGKRGGDQLLVDR
STNQLYVVMPGGGELRPVYNLTSARLVLGNPGTPVAVKSEELNRMSKGQPIGIPGAPYATPVSGAAESMWTLCDTVTKPE
SVVPRVETSVLVRPLVVDSTVGPLRPDQGMLVSFKGANWLVTEGGRHSIDLADRAVTSAVGIPVTARATPISEGLFNALP
NAGPWQLPQVARAGEPNTVGLPANLVIGSVFETVTESDDQQHYVVLADGVARVNDPTAAALRATNSYGLIEPPMVEASVV
ARIPEQVYVSPLPDKALDILLRQDDPTLCWSWQRVAGDQAPRTTVIAGRRLPIAASALNTGIRQITGDSTVYIDGGQFIR
LQSPDPRYGESLYYIDPQGVRYGVSDEETAKNLGLVGPLTAPWQVVSLLVDGPVLSKQAALLEHDTLPANPNPRKVGEDG
PVAGARPGGSR

Sequences:

>Translated_491_residues
MASFRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRAVGAGIIIAVLICLGAALMAYFKPLGKRGGDQLLVDR
STNQLYVVMPGGGELRPVYNLTSARLVLGNPGTPVAVKSEELNRMSKGQPIGIPGAPYATPVSGAAESMWTLCDTVTKPE
SVVPRVETSVLVRPLVVDSTVGPLRPDQGMLVSFKGANWLVTEGGRHSIDLADRAVTSAVGIPVTARATPISEGLFNALP
NAGPWQLPQVARAGEPNTVGLPANLVIGSVFETVTESDDQQHYVVLADGVARVNDPTAAALRATNSYGLIEPPMVEASVV
ARIPEQVYVSPLPDKALDILLRQDDPTLCWSWQRVAGDQAPRTTVIAGRRLPIAASALNTGIRQITGDSTVYIDGGQFIR
LQSPDPRYGESLYYIDPQGVRYGVSDEETAKNLGLVGPLTAPWQVVSLLVDGPVLSKQAALLEHDTLPANPNPRKVGEDG
PVAGARPGGSR
>Mature_490_residues
ASFRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRAVGAGIIIAVLICLGAALMAYFKPLGKRGGDQLLVDRS
TNQLYVVMPGGGELRPVYNLTSARLVLGNPGTPVAVKSEELNRMSKGQPIGIPGAPYATPVSGAAESMWTLCDTVTKPES
VVPRVETSVLVRPLVVDSTVGPLRPDQGMLVSFKGANWLVTEGGRHSIDLADRAVTSAVGIPVTARATPISEGLFNALPN
AGPWQLPQVARAGEPNTVGLPANLVIGSVFETVTESDDQQHYVVLADGVARVNDPTAAALRATNSYGLIEPPMVEASVVA
RIPEQVYVSPLPDKALDILLRQDDPTLCWSWQRVAGDQAPRTTVIAGRRLPIAASALNTGIRQITGDSTVYIDGGQFIRL
QSPDPRYGESLYYIDPQGVRYGVSDEETAKNLGLVGPLTAPWQVVSLLVDGPVLSKQAALLEHDTLPANPNPRKVGEDGP
VAGARPGGSR

Specific function: Probably part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eccB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007795 [H]

Pfam domain/function: PF05108 DUF690 [H]

EC number: NA

Molecular weight: Translated: 52480; Mature: 52348

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRAVGAGIIIAVLICLGAA
CCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMAYFKPLGKRGGDQLLVDRSTNQLYVVMPGGGELRPVYNLTSARLVLGNPGTPVAVKSE
HHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCEEEECCCCEEEECCCCCCEEEEHH
ELNRMSKGQPIGIPGAPYATPVSGAAESMWTLCDTVTKPESVVPRVETSVLVRPLVVDST
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHEEEEEEECCC
VGPLRPDQGMLVSFKGANWLVTEGGRHSIDLADRAVTSAVGIPVTARATPISEGLFNALP
CCCCCCCCCCEEEECCCCEEEECCCCCEECHHHHHHHHHCCCCEEECCCCHHHHHHHHCC
NAGPWQLPQVARAGEPNTVGLPANLVIGSVFETVTESDDQQHYVVLADGVARVNDPTAAA
CCCCCCCCHHHHCCCCCEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEECCCCCHHH
LRATNSYGLIEPPMVEASVVARIPEQVYVSPLPDKALDILLRQDDPTLCWSWQRVAGDQA
EEECCCCCCCCCCCHHHHHHHHCCHHEEECCCCCHHHEEEEECCCCCEEEEHHHHCCCCC
PRTTVIAGRRLPIAASALNTGIRQITGDSTVYIDGGQFIRLQSPDPRYGESLYYIDPQGV
CCEEEEECCCCCEEHHHHHCCHHHCCCCCEEEECCCEEEEECCCCCCCCCEEEEECCCCC
RYGVSDEETAKNLGLVGPLTAPWQVVSLLVDGPVLSKQAALLEHDTLPANPNPRKVGEDG
EECCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PVAGARPGGSR
CCCCCCCCCCC
>Mature Secondary Structure 
ASFRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRAVGAGIIIAVLICLGAA
CCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMAYFKPLGKRGGDQLLVDRSTNQLYVVMPGGGELRPVYNLTSARLVLGNPGTPVAVKSE
HHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCEEEECCCCEEEECCCCCCEEEEHH
ELNRMSKGQPIGIPGAPYATPVSGAAESMWTLCDTVTKPESVVPRVETSVLVRPLVVDST
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHEEEEEEECCC
VGPLRPDQGMLVSFKGANWLVTEGGRHSIDLADRAVTSAVGIPVTARATPISEGLFNALP
CCCCCCCCCCEEEECCCCEEEECCCCCEECHHHHHHHHHCCCCEEECCCCHHHHHHHHCC
NAGPWQLPQVARAGEPNTVGLPANLVIGSVFETVTESDDQQHYVVLADGVARVNDPTAAA
CCCCCCCCHHHHCCCCCEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEECCCCCHHH
LRATNSYGLIEPPMVEASVVARIPEQVYVSPLPDKALDILLRQDDPTLCWSWQRVAGDQA
EEECCCCCCCCCCCHHHHHHHHCCHHEEECCCCCHHHEEEEECCCCCEEEEHHHHCCCCC
PRTTVIAGRRLPIAASALNTGIRQITGDSTVYIDGGQFIRLQSPDPRYGESLYYIDPQGV
CCEEEEECCCCCEEHHHHHCCHHHCCCCCEEEECCCEEEEECCCCCCCCCEEEEECCCCC
RYGVSDEETAKNLGLVGPLTAPWQVVSLLVDGPVLSKQAALLEHDTLPANPNPRKVGEDG
EECCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PVAGARPGGSR
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]