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The map label for this gene is rcsC [H]

Identifier: 108763719

GI number: 108763719

Start: 6823820

End: 6825556

Strand: Reverse

Name: rcsC [H]

Synonym: MXAN_5483

Alternate gene names: 108763719

Gene position: 6825556-6823820 (Counterclockwise)

Preceding gene: 108762904

Following gene: 108762127

Centisome position: 74.68

GC content: 70.7

Gene sequence:

>1737_bases
GTGGGCGCGGCGGAAATGTTAAGCGGCAGGTACATCGCCTTGGCCCGTTCTCACACCGACCGCGTGGACTCACTCTCGAC
CGGACAGGACCCTGATGGCGCCAGCCACGGCGGGTCGGACACCAGCGGGCTGGATACCGCCCTGCTGGACCAGATGCCGG
AAGCGGTCGTGGTCTGCTCGCTGGACGCAGTCTGTGTCCATGTGAATCCCTCCCTGGAGCGGCACCTGGGCCGGCCGCGC
CAGGAGCTGCTCGGCCGGAGGCTCTGGGAGCTGCACCCGGAGTGGACGGAACGTTCCTTTCAGGAGCGCTTCCGCCAGGT
GGTCCGGACGGGCGAATCCGCCGAGTTCGAACGCCACGCCGAGCCCCAGGACCGCTGGTTCGTGAAACGGCTGTTTCGCG
TCCATGAGCGGGTCGTCCTGTTCTCGCGGGACATCAGCGCGGAGAAGAAGCAGGAGGCGACGCTTCGGGCCCTCTACGAC
GAGATGCGCCGGGCGCAGCGGCACGCGGCCTTCCTGGCGCAGGCCAGCGAGGTGCTGGCGTCGTCCCTGGAGCACGACCT
CATCCTGCAGCGCATGGCCCACCTCGCCGTTCCCATCCTGGGAGACGCGTGCTCGGTGGACCTCCCCATGCCGGATGGGC
AGGTGCGCCGCGCCGCCGCCGCCTTCTCCAGACAGGAGATGGTGGCGCCCGCGCAGGACTTCCAGACGCGCTATCCCATT
CGCCTGGAGGACGCGGCGGGTATCGGCAAGGTGCTGCGTACTGGCGTCACCGAGTTCACCCCGGACTTTCCCGCCATGCT
CGCCGCCGCCCAGGGGGGCAGCTCGGCGTACCGGCGGGACGTGGAGGCGCTGGGCATCAGCGCGTACATCATCGTCCCGC
TCATCAGCCGGGGCCGGGTGCTGGGGGCGCTCACGCTGCTCAATTCGGAGTCCCGGCGCAGATACACGGAGGCGGACGTG
CGGCTGGCGGAAGACCTGGCCCGGCGCGCCGCCACCTCGCTGGACAACGGTCGGCTCTACACGGAGGCGCAGGAGGCCGT
GCGCGCCCGGGACTCGTTCCTGTCCGTGGCATCTCACGAGCTCAACACGCCGCTGACCTCGCTCATGCTCAACATCCAGG
CGTTGCGGCGCGACATGGAGCCGCGCGCCAGCAATGGCCCCGCGTCACCGGAGGCGCTCTCCACGAAGGTGGTGGCGGTG
CAGCGGCAGGTCTCCCGCCTGTCGAGCCTGGTGCGCGAGCTGCTGGACGTGTCCCGCATCACCGCGGGGCGGCTGCGGCT
GGAGCGCGAGGACCTGGACCTGGCCGCGCTCACCCGCGAGGTGGTGCCCCGCTTCACCGAGGACCTGGCACGCGCGGGCT
GCGCGCTGCACTTGGAGGCGGGGGGCGCCGCCACCGGCCATTGGGACCGGCTGCGGCTGGAGCAGGTGCTGCAGAACCTG
CTCTCCAACGCCATCAAGTACGGCCGGGGCCGCCCCATTGAAGTGCGGGTGGGGGCGGATGCGTCGCGCGCCTGTCTGTC
GGTGAAGGACCAGGGCGTGGGCATTCCGCCGGAGGGGCGCGCGCGTCTCTTCCAGCGCTTCGAGCGGCTGGCCAGCGAGC
GGCACTACGGCGGACTGGGGCTGGGCCTGTGGATCGTGAAGCAGATTGTGGACGCCATGGAGGGTCGCATCCTCGTGGAG
AGCGTGCCCGGCCAGGGCTCCACCTTCATCGTGGAGCTGCCGCGCCACCCTGCGTGA

Upstream 100 bases:

>100_bases
CTTCGCGGGCGCGCCCGGCACGCCACGGGGTGGGAAAGGGCGTTTCCCCGAGCGGCGAGAATGTCGGCTGCCTTGCAGAT
TTCCGGCGCGTGACGGTGCG

Downstream 100 bases:

>100_bases
CCAGGTGCGAGCGGACGCCGGAGGACACCACCCAGAGCTGATGGGAGGTGCGCGTCACCGCCACGTGCAGGCGGCGGCGT
GACTCGTCGTCCACCGGGTA

Product: sensory box histidine kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MGAAEMLSGRYIALARSHTDRVDSLSTGQDPDGASHGGSDTSGLDTALLDQMPEAVVVCSLDAVCVHVNPSLERHLGRPR
QELLGRRLWELHPEWTERSFQERFRQVVRTGESAEFERHAEPQDRWFVKRLFRVHERVVLFSRDISAEKKQEATLRALYD
EMRRAQRHAAFLAQASEVLASSLEHDLILQRMAHLAVPILGDACSVDLPMPDGQVRRAAAAFSRQEMVAPAQDFQTRYPI
RLEDAAGIGKVLRTGVTEFTPDFPAMLAAAQGGSSAYRRDVEALGISAYIIVPLISRGRVLGALTLLNSESRRRYTEADV
RLAEDLARRAATSLDNGRLYTEAQEAVRARDSFLSVASHELNTPLTSLMLNIQALRRDMEPRASNGPASPEALSTKVVAV
QRQVSRLSSLVRELLDVSRITAGRLRLEREDLDLAALTREVVPRFTEDLARAGCALHLEAGGAATGHWDRLRLEQVLQNL
LSNAIKYGRGRPIEVRVGADASRACLSVKDQGVGIPPEGRARLFQRFERLASERHYGGLGLGLWIVKQIVDAMEGRILVE
SVPGQGSTFIVELPRHPA

Sequences:

>Translated_578_residues
MGAAEMLSGRYIALARSHTDRVDSLSTGQDPDGASHGGSDTSGLDTALLDQMPEAVVVCSLDAVCVHVNPSLERHLGRPR
QELLGRRLWELHPEWTERSFQERFRQVVRTGESAEFERHAEPQDRWFVKRLFRVHERVVLFSRDISAEKKQEATLRALYD
EMRRAQRHAAFLAQASEVLASSLEHDLILQRMAHLAVPILGDACSVDLPMPDGQVRRAAAAFSRQEMVAPAQDFQTRYPI
RLEDAAGIGKVLRTGVTEFTPDFPAMLAAAQGGSSAYRRDVEALGISAYIIVPLISRGRVLGALTLLNSESRRRYTEADV
RLAEDLARRAATSLDNGRLYTEAQEAVRARDSFLSVASHELNTPLTSLMLNIQALRRDMEPRASNGPASPEALSTKVVAV
QRQVSRLSSLVRELLDVSRITAGRLRLEREDLDLAALTREVVPRFTEDLARAGCALHLEAGGAATGHWDRLRLEQVLQNL
LSNAIKYGRGRPIEVRVGADASRACLSVKDQGVGIPPEGRARLFQRFERLASERHYGGLGLGLWIVKQIVDAMEGRILVE
SVPGQGSTFIVELPRHPA
>Mature_577_residues
GAAEMLSGRYIALARSHTDRVDSLSTGQDPDGASHGGSDTSGLDTALLDQMPEAVVVCSLDAVCVHVNPSLERHLGRPRQ
ELLGRRLWELHPEWTERSFQERFRQVVRTGESAEFERHAEPQDRWFVKRLFRVHERVVLFSRDISAEKKQEATLRALYDE
MRRAQRHAAFLAQASEVLASSLEHDLILQRMAHLAVPILGDACSVDLPMPDGQVRRAAAAFSRQEMVAPAQDFQTRYPIR
LEDAAGIGKVLRTGVTEFTPDFPAMLAAAQGGSSAYRRDVEALGISAYIIVPLISRGRVLGALTLLNSESRRRYTEADVR
LAEDLARRAATSLDNGRLYTEAQEAVRARDSFLSVASHELNTPLTSLMLNIQALRRDMEPRASNGPASPEALSTKVVAVQ
RQVSRLSSLVRELLDVSRITAGRLRLEREDLDLAALTREVVPRFTEDLARAGCALHLEAGGAATGHWDRLRLEQVLQNLL
SNAIKYGRGRPIEVRVGADASRACLSVKDQGVGIPPEGRARLFQRFERLASERHYGGLGLGLWIVKQIVDAMEGRILVES
VPGQGSTFIVELPRHPA

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=29.4117647058824, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=33.0508474576271, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786600, Length=286, Percent_Identity=33.2167832167832, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=29.6747967479675, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=309, Percent_Identity=31.0679611650485, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=30.3501945525292, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=30.5439330543933, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790346, Length=246, Percent_Identity=28.8617886178862, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=33.1896551724138, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=30.2127659574468, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=26.4462809917355, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=30.379746835443, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=211, Percent_Identity=28.9099526066351, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=28.4, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=286, Percent_Identity=25.8741258741259, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=31.5068493150685, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63946; Mature: 63814

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAAEMLSGRYIALARSHTDRVDSLSTGQDPDGASHGGSDTSGLDTALLDQMPEAVVVCS
CCCHHHHCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEE
LDAVCVHVNPSLERHLGRPRQELLGRRLWELHPEWTERSFQERFRQVVRTGESAEFERHA
CCEEEEEECCHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCC
EPQDRWFVKRLFRVHERVVLFSRDISAEKKQEATLRALYDEMRRAQRHAAFLAQASEVLA
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLEHDLILQRMAHLAVPILGDACSVDLPMPDGQVRRAAAAFSRQEMVAPAQDFQTRYPI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCE
RLEDAAGIGKVLRTGVTEFTPDFPAMLAAAQGGSSAYRRDVEALGISAYIIVPLISRGRV
EECCCCHHHHHHHCCCHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCHH
LGALTLLNSESRRRYTEADVRLAEDLARRAATSLDNGRLYTEAQEAVRARDSFLSVASHE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LNTPLTSLMLNIQALRRDMEPRASNGPASPEALSTKVVAVQRQVSRLSSLVRELLDVSRI
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAGRLRLEREDLDLAALTREVVPRFTEDLARAGCALHLEAGGAATGHWDRLRLEQVLQNL
HHHHHEEEHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHH
LSNAIKYGRGRPIEVRVGADASRACLSVKDQGVGIPPEGRARLFQRFERLASERHYGGLG
HHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCH
LGLWIVKQIVDAMEGRILVESVPGQGSTFIVELPRHPA
HHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCC
>Mature Secondary Structure 
GAAEMLSGRYIALARSHTDRVDSLSTGQDPDGASHGGSDTSGLDTALLDQMPEAVVVCS
CCHHHHCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEE
LDAVCVHVNPSLERHLGRPRQELLGRRLWELHPEWTERSFQERFRQVVRTGESAEFERHA
CCEEEEEECCHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCC
EPQDRWFVKRLFRVHERVVLFSRDISAEKKQEATLRALYDEMRRAQRHAAFLAQASEVLA
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLEHDLILQRMAHLAVPILGDACSVDLPMPDGQVRRAAAAFSRQEMVAPAQDFQTRYPI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCE
RLEDAAGIGKVLRTGVTEFTPDFPAMLAAAQGGSSAYRRDVEALGISAYIIVPLISRGRV
EECCCCHHHHHHHCCCHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCHH
LGALTLLNSESRRRYTEADVRLAEDLARRAATSLDNGRLYTEAQEAVRARDSFLSVASHE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LNTPLTSLMLNIQALRRDMEPRASNGPASPEALSTKVVAVQRQVSRLSSLVRELLDVSRI
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAGRLRLEREDLDLAALTREVVPRFTEDLARAGCALHLEAGGAATGHWDRLRLEQVLQNL
HHHHHEEEHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHH
LSNAIKYGRGRPIEVRVGADASRACLSVKDQGVGIPPEGRARLFQRFERLASERHYGGLG
HHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCH
LGLWIVKQIVDAMEGRILVESVPGQGSTFIVELPRHPA
HHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]