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The map label for this gene is speE [H]

Identifier: 108762127

GI number: 108762127

Start: 6820724

End: 6821638

Strand: Reverse

Name: speE [H]

Synonym: MXAN_5481

Alternate gene names: 108762127

Gene position: 6821638-6820724 (Counterclockwise)

Preceding gene: 108763719

Following gene: 108761179

Centisome position: 74.64

GC content: 67.98

Gene sequence:

>915_bases
ATGGACATGCGCGGTGTGACCCAGCGGCTGCTGCTGATGGGGCTGGTGGTCCTGGCATGTACGGCCTCCGCGTCCCGCAA
GGTCTTGTACGAGAAGGAATCGCCCTACACCCTCATCTCGGTGACGGAGGACGAAGAGGGGCGCCGGTACCTGGGCTTCG
ATGCCTCGGGGGCGCTGCAGAGCGTGGTCCGGCCGGGCAAGCCGCTGGACCTGGTGCTGCCCTACACGCAGGTCTCCATG
GTGGGGCTGGCCTATGTGCCCGCGCCCAAGCGCATCCTCATCGTGGGGCTGGGGGGCGGGGCCATGCCCATGTTCCTGCG
CAAGGTAGTGCCGCGGGCGCACATCGACGTGGTGGACATCGATCCGGATGTGGTGACGGTGGCAAGGCGCTACTTCGGCT
TCCGGGAGGATACGCACCTGCGCGCGCACGTCGGAGACGGCCGGCGCTTCATCGAAGCCGAGCGGCCCGCGTATGACCTC
ATCTTCCTGGATGCCTATGGCCCGGACAGCATCCCCGAGCACCTGGCCACGCAGGAGTTCCTGGCGGTGGTGCGCGCGAA
GCTGAGCCCCCAGGGCGCGGTGGTGGGCAACGTGTGGGCCTTTCCGCCCAACCGTCACTACGACGCCATGGTGCACACGT
GGCAGGTGGCCTTCACGCAGCTGTATGAGTTCATCGTGCCGCAGAGCTCGAATCGCATCCTGGTGGGCGTGGGGTACGAG
GAGAAGGTGGCCGCCAAGACGCTGGAGGCGCGCGCGGAGAAGCTGGAGCGCACCCGGGGCGTGCCATTCGACTTGAGCGG
GCTGGTGGACCGGGGCTACACGGATGCGACGGAGCGGCAGCTGCGAGGCAAGGTGCTGAAGGACGCGGACCTGCCGAAGC
CCGAGTCTGTAACGACGCCGGCGCAGGTCCGCTGA

Upstream 100 bases:

>100_bases
TGGCTCATGCGCGGCAAGGTGAACCTCGGCGCCGTATGCGTCAACCTGTTGTTTTTCCTGAAGGAAATGCTGTCTTTTTG
GTACTCTGTACCAGGAAGGG

Downstream 100 bases:

>100_bases
GCGTTTGTAGGGGGCTCGGGCCTGCCTCACATGGACGCGTCTGCCTTCAGCGGTCCGTCCATGGGGGTGACCACGCCTTG
GGATGCCGATAGCGGTCCTT

Product: putative lipoprotein

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDMRGVTQRLLLMGLVVLACTASASRKVLYEKESPYTLISVTEDEEGRRYLGFDASGALQSVVRPGKPLDLVLPYTQVSM
VGLAYVPAPKRILIVGLGGGAMPMFLRKVVPRAHIDVVDIDPDVVTVARRYFGFREDTHLRAHVGDGRRFIEAERPAYDL
IFLDAYGPDSIPEHLATQEFLAVVRAKLSPQGAVVGNVWAFPPNRHYDAMVHTWQVAFTQLYEFIVPQSSNRILVGVGYE
EKVAAKTLEARAEKLERTRGVPFDLSGLVDRGYTDATERQLRGKVLKDADLPKPESVTTPAQVR

Sequences:

>Translated_304_residues
MDMRGVTQRLLLMGLVVLACTASASRKVLYEKESPYTLISVTEDEEGRRYLGFDASGALQSVVRPGKPLDLVLPYTQVSM
VGLAYVPAPKRILIVGLGGGAMPMFLRKVVPRAHIDVVDIDPDVVTVARRYFGFREDTHLRAHVGDGRRFIEAERPAYDL
IFLDAYGPDSIPEHLATQEFLAVVRAKLSPQGAVVGNVWAFPPNRHYDAMVHTWQVAFTQLYEFIVPQSSNRILVGVGYE
EKVAAKTLEARAEKLERTRGVPFDLSGLVDRGYTDATERQLRGKVLKDADLPKPESVTTPAQVR
>Mature_304_residues
MDMRGVTQRLLLMGLVVLACTASASRKVLYEKESPYTLISVTEDEEGRRYLGFDASGALQSVVRPGKPLDLVLPYTQVSM
VGLAYVPAPKRILIVGLGGGAMPMFLRKVVPRAHIDVVDIDPDVVTVARRYFGFREDTHLRAHVGDGRRFIEAERPAYDL
IFLDAYGPDSIPEHLATQEFLAVVRAKLSPQGAVVGNVWAFPPNRHYDAMVHTWQVAFTQLYEFIVPQSSNRILVGVGYE
EKVAAKTLEARAEKLERTRGVPFDLSGLVDRGYTDATERQLRGKVLKDADLPKPESVTTPAQVR

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Homo sapiens, GI55956895, Length=235, Percent_Identity=29.3617021276596, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI42542403, Length=234, Percent_Identity=29.4871794871795, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI42542405, Length=234, Percent_Identity=29.4871794871795, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17570359, Length=85, Percent_Identity=42.3529411764706, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 33748; Mature: 33748

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMRGVTQRLLLMGLVVLACTASASRKVLYEKESPYTLISVTEDEEGRRYLGFDASGALQ
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCEEECCCCHHHHH
SVVRPGKPLDLVLPYTQVSMVGLAYVPAPKRILIVGLGGGAMPMFLRKVVPRAHIDVVDI
HHHCCCCCEEEEECHHHHHHHEEEECCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEEC
DPDVVTVARRYFGFREDTHLRAHVGDGRRFIEAERPAYDLIFLDAYGPDSIPEHLATQEF
CCHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHH
LAVVRAKLSPQGAVVGNVWAFPPNRHYDAMVHTWQVAFTQLYEFIVPQSSNRILVGVGYE
HHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCH
EKVAAKTLEARAEKLERTRGVPFDLSGLVDRGYTDATERQLRGKVLKDADLPKPESVTTP
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
AQVR
CCCC
>Mature Secondary Structure
MDMRGVTQRLLLMGLVVLACTASASRKVLYEKESPYTLISVTEDEEGRRYLGFDASGALQ
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCEEECCCCHHHHH
SVVRPGKPLDLVLPYTQVSMVGLAYVPAPKRILIVGLGGGAMPMFLRKVVPRAHIDVVDI
HHHCCCCCEEEEECHHHHHHHEEEECCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEEC
DPDVVTVARRYFGFREDTHLRAHVGDGRRFIEAERPAYDLIFLDAYGPDSIPEHLATQEF
CCHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHH
LAVVRAKLSPQGAVVGNVWAFPPNRHYDAMVHTWQVAFTQLYEFIVPQSSNRILVGVGYE
HHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCH
EKVAAKTLEARAEKLERTRGVPFDLSGLVDRGYTDATERQLRGKVLKDADLPKPESVTTP
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
AQVR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA