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The map label for this gene is plsC [H]

Identifier: 108763614

GI number: 108763614

Start: 6929829

End: 6930566

Strand: Reverse

Name: plsC [H]

Synonym: MXAN_5578

Alternate gene names: 108763614

Gene position: 6930566-6929829 (Counterclockwise)

Preceding gene: 108758409

Following gene: 108759794

Centisome position: 75.83

GC content: 70.33

Gene sequence:

>738_bases
TTGATTCGCAAGCTCCTGCAGACGGCCTTTGCTGGAACGGCGGCGGTGGGCATCACCGGTGTGCTGTCTCCCGTGGTGTC
GGCGCTGTCGCTGCGCGACGCCAAGGACGCGGACGGCGTGCTGGTGCTGTGGGCGCGCTCGCTGCTGGCGTCCGCGGGGG
TGCGGCACGAGGCGGTGGGCGTCGAGAACGTCCCCACCGACACCCACGTCGTCTTCGTGAGCAACCACCAGTCGCACTAC
GACGCGCTGGTGAACTTCGCCCACATCCGCAAGCACACGCGTTACGTGGCGAAGGCGGAGCTGTTCCGCATCCCCGTCTT
CGGGCCCGCGCTCCGGCGCGCGGGCAACATCCCAGTGGAGCGCACCGGGGGGGCGGGAGACAGGGCCCGCCTGTCGGAAG
CCGTCACGGCGCTGCGGGAACGGGTGAGCGTGCTCTTCTTCGCGGAAGGCACGCGCAGCACGGATGGGCGGCTGCGGCCG
TTCAAGAAGGGAGCCGCGACGCTGGCCATCCAGGCGGGCGTTCCGGTGGTGCCCCTGGCCGTGTCAGGGACGCGCCTCAT
TCTTCCCAAGGGGGGTCGGGCCGTGCGGTGGGGACAGCGCGTGGCGCTGGTGGTGGGAAAGCCCATCCCCACCCAGGGAC
TGACGATGCAGGACCGCGACGCGCTCACGCGCCAGTTGGAAGACGCGGTCGCAGAACTCTATGCCGAGGCCTGCAAGCGC
TCGGGAGACACGCCATGA

Upstream 100 bases:

>100_bases
CCTCGGCGGGCATCGCCGTCGGGCTCGATAGAATCCTGATGCTGCTGCTCGGGGTCCAGCGCATCTCGGACGTGCTCCTT
TTCCCCGCCCACGAGTTCGT

Downstream 100 bases:

>100_bases
AGAAGCCAATCCAGACCACATCCCAGGCGCACCCGTGGCACGGAATCACCCCGGGCGAGGACGCCCCCGAAATCGTCACC
GCGTACATCGAAATCGTCCC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MIRKLLQTAFAGTAAVGITGVLSPVVSALSLRDAKDADGVLVLWARSLLASAGVRHEAVGVENVPTDTHVVFVSNHQSHY
DALVNFAHIRKHTRYVAKAELFRIPVFGPALRRAGNIPVERTGGAGDRARLSEAVTALRERVSVLFFAEGTRSTDGRLRP
FKKGAATLAIQAGVPVVPLAVSGTRLILPKGGRAVRWGQRVALVVGKPIPTQGLTMQDRDALTRQLEDAVAELYAEACKR
SGDTP

Sequences:

>Translated_245_residues
MIRKLLQTAFAGTAAVGITGVLSPVVSALSLRDAKDADGVLVLWARSLLASAGVRHEAVGVENVPTDTHVVFVSNHQSHY
DALVNFAHIRKHTRYVAKAELFRIPVFGPALRRAGNIPVERTGGAGDRARLSEAVTALRERVSVLFFAEGTRSTDGRLRP
FKKGAATLAIQAGVPVVPLAVSGTRLILPKGGRAVRWGQRVALVVGKPIPTQGLTMQDRDALTRQLEDAVAELYAEACKR
SGDTP
>Mature_245_residues
MIRKLLQTAFAGTAAVGITGVLSPVVSALSLRDAKDADGVLVLWARSLLASAGVRHEAVGVENVPTDTHVVFVSNHQSHY
DALVNFAHIRKHTRYVAKAELFRIPVFGPALRRAGNIPVERTGGAGDRARLSEAVTALRERVSVLFFAEGTRSTDGRLRP
FKKGAATLAIQAGVPVVPLAVSGTRLILPKGGRAVRWGQRVALVVGKPIPTQGLTMQDRDALTRQLEDAVAELYAEACKR
SGDTP

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=185, Percent_Identity=35.6756756756757, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI15100175, Length=185, Percent_Identity=35.6756756756757, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI6041665, Length=187, Percent_Identity=32.0855614973262, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1789395, Length=125, Percent_Identity=36, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564032, Length=211, Percent_Identity=28.436018957346, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641614, Length=204, Percent_Identity=32.843137254902, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24641612, Length=204, Percent_Identity=32.843137254902, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281364648, Length=155, Percent_Identity=32.9032258064516, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582856, Length=155, Percent_Identity=32.9032258064516, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582854, Length=155, Percent_Identity=32.9032258064516, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26168; Mature: 26168

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKLLQTAFAGTAAVGITGVLSPVVSALSLRDAKDADGVLVLWARSLLASAGVRHEAVG
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCHHCCC
VENVPTDTHVVFVSNHQSHYDALVNFAHIRKHTRYVAKAELFRIPVFGPALRRAGNIPVE
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHCCCCCCC
RTGGAGDRARLSEAVTALRERVSVLFFAEGTRSTDGRLRPFKKGAATLAIQAGVPVVPLA
CCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEEE
VSGTRLILPKGGRAVRWGQRVALVVGKPIPTQGLTMQDRDALTRQLEDAVAELYAEACKR
ECCCEEEEECCCCEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGDTP
CCCCC
>Mature Secondary Structure
MIRKLLQTAFAGTAAVGITGVLSPVVSALSLRDAKDADGVLVLWARSLLASAGVRHEAVG
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCHHCCC
VENVPTDTHVVFVSNHQSHYDALVNFAHIRKHTRYVAKAELFRIPVFGPALRRAGNIPVE
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHCCCCCCC
RTGGAGDRARLSEAVTALRERVSVLFFAEGTRSTDGRLRPFKKGAATLAIQAGVPVVPLA
CCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEEE
VSGTRLILPKGGRAVRWGQRVALVVGKPIPTQGLTMQDRDALTRQLEDAVAELYAEACKR
ECCCEEEEECCCCEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGDTP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]