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The map label for this gene is atoS [H]

Identifier: 108763456

GI number: 108763456

Start: 5716346

End: 5718484

Strand: Direct

Name: atoS [H]

Synonym: MXAN_4579

Alternate gene names: 108763456

Gene position: 5716346-5718484 (Clockwise)

Preceding gene: 108757693

Following gene: 108757358

Centisome position: 62.54

GC content: 71.86

Gene sequence:

>2139_bases
GTGTCGCCCCTGCGTCCCGTGTTCATGCGCCTGCCTGTCCTCCCCGTGCTGCTGCTGTGTCTGATGCTCTCTGGCGTCAT
CGCGGGCGTCCTGCACTTCATGCAGCGCGACCGGCAAGCGCTGGTGGACCAGATGGCCCGCGAGCGACAGGCGCAGCTCC
TGGAGGCCGTGCGCGGCGTCTCCGCCGCCCTGGAGAGCGCGGAGGAGGACCTGCGCTTCGCGGGCGAGCTGCTGGCCCAG
CCGGGCACCGCCGAGGAGCACCGGCGCGAGATGCGCGCCCTGCTGGAGGCGGTGGGTCAGTACAAGGCCATCCTCGTCTT
CGGCACGGATGGACAGGAACGGCTCCGACTGGTGGACCGGCGCAGCGCGGCGGCGATGACGCACCAGTTCACCGCGGAGG
ACCTGGCCCTCACCGTGGCGCAGGCCCGCAGTCATCCGCCGGGCCACGTCATCTCATCCCCGCCCCTTCCCCGGGCCCAA
TCGGGCTGGCTGCGCGCCTTCGCCACCGCGTTGCCGGAGGACGCGCAGGACAGCGGCGGCGTCGTCGTGGTGCTGGTGGA
CGCCGAGCCGCGCTTCGCCCCGCTGAAGCTGCTCGCGTCGGACTCGGAGACGCAACTTCTGGTGCTGGGAGTCCATGGAA
CGCCGACGGCGTTGACCCACCCGAACCTGGCGGACAGGTACCGGCGGTTGGACACCGACGGCCACCAGACGCCCGGCCTC
GCGGCGCTGGCGCGGGCGCTTCGCGCGGGTGAGTCGGGCACGCGCATCATCGAGCGCAAGGAGGCCGCCCGGCTCGGCCT
GGGCGACTCGGAGGTGGTGGCCACCTTCAGCCCGGTGCGGTTCAAGAATGGCGCGGCATGGCCGGTGGCGACGCTCGCGT
CGACGCGCGTGCTCCGGATCCATGAGCGCGGCCTGGTGCTGCGCCTGTCGCTGGCGGCGGTGCTCGTCTCCGGGTTCCTC
ATCGCCTTCGGAGTGTACGTGGTGCTCGCGCGCAGCCGGGCGGAAGCCCTGCGGGACAGCCAGCTCCATGCGCAGCGGCT
GGCGCACCTGCACGACAAGACGCAGAAGATTCTCGACAACATCCCCACCGGGGTCCTGGCGCTCTCCTCCACCCGGCACA
TCTCCGCCGCCAACCGCGCGCTGAGCGCCCGCATGCCGGCGGACGTCGTGGGCCAGCCCCTGACGGCGGCCTTTCCCCAG
GCCCAGGCCCCCGTCATCCAGCGACTGGAGGACCTGGTCCACGCGGCCACGAGCGACGGCCGGGTGCGCAGCCTCCACGG
TGAACCGCTCTGCCTCTTCGAAGAGCCCGGCCAGTACAACGTCCACGCGGTGCCGCTGGAGCCGAACACGCCGGAGGTCC
ACACGCTGGTCGTCATCGAGGACCTGAGCAGCCTGCGCGCGCTGGAAGGACAACTGCTGCGCGCGGAGAAGCTGGCCACG
GTGGGCGTGCTGGCGGCGGGCATCGCCCATGAGATTGGCACGCCGCTGGGCATCGTCCGCGGCCGGGCCGAGTACGTGCA
GGAGAAGCTGGGACGCGAGCACCCGCAGGCGGCCGGCCTGGGCACCATCGTCGGGCAGATAGACAGGGTGAGCCGGACGC
TGCGCCAGTTGCTCGACTTCTCCCGGCTCCGGCCAGCGGACGCGCAGACAGTCCCACTGGAGCCCCTGGTGCACAGCGTG
CGGGAGTTGCTGTGGATGGAGGCCGAGCGGCGGCGCCTGAAGCTGGAGGTGACGGTCGCCTCGCCCGTGCCCGCGGTGGC
GGCCGACCCCGACCAGTTCCAGCAGGTGCTCATCAACCTGGTGCTCAACGCGTGTGACGCGTGCGGGGCCGGCGGACGCG
TCCGGCTGAGCGCGAGCATGGACACCGGAGACACACCGGGCGCCTGGGGCATGGTGCGCGTGGACGTCGAGGACAACGGC
TGCGGTATCGCCCCCCGCCACGTCCACCAGGTCTTCGACCCTTTCTTCACCACCAAGAAGCGCGGCCAGGGCACCGGACT
GGGCCTGACGATGGTGGCGCACATCGTGCGCAACCACGGAGGCCGTATCGAACTGGACAGCGCGCCAGAGCGAGGCACCC
GCGTCACCGTGCGCTGGCCCGCCGCGGCACCCGCCGGAGAGGAGCGACATGTCGTCTAG

Upstream 100 bases:

>100_bases
AGCCGGGGGGCACGGGCGTTGCTACCGGAGGAGCTTTCCTCCGGGACGAAGCGCTGCCAGGCGGCGTGGAGGCCCGGCAA
GCACCGGAGCCCCCGCGCCG

Downstream 100 bases:

>100_bases
AGCCAGGGTCCTCGTCGTCGACGACCACGTCGAGATGGGGCAGATGTTGAAGGAACCGCTGACGGACGACGGCTACAAGG
TCGACATCGCCACCGGCGGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MSPLRPVFMRLPVLPVLLLCLMLSGVIAGVLHFMQRDRQALVDQMARERQAQLLEAVRGVSAALESAEEDLRFAGELLAQ
PGTAEEHRREMRALLEAVGQYKAILVFGTDGQERLRLVDRRSAAAMTHQFTAEDLALTVAQARSHPPGHVISSPPLPRAQ
SGWLRAFATALPEDAQDSGGVVVVLVDAEPRFAPLKLLASDSETQLLVLGVHGTPTALTHPNLADRYRRLDTDGHQTPGL
AALARALRAGESGTRIIERKEAARLGLGDSEVVATFSPVRFKNGAAWPVATLASTRVLRIHERGLVLRLSLAAVLVSGFL
IAFGVYVVLARSRAEALRDSQLHAQRLAHLHDKTQKILDNIPTGVLALSSTRHISAANRALSARMPADVVGQPLTAAFPQ
AQAPVIQRLEDLVHAATSDGRVRSLHGEPLCLFEEPGQYNVHAVPLEPNTPEVHTLVVIEDLSSLRALEGQLLRAEKLAT
VGVLAAGIAHEIGTPLGIVRGRAEYVQEKLGREHPQAAGLGTIVGQIDRVSRTLRQLLDFSRLRPADAQTVPLEPLVHSV
RELLWMEAERRRLKLEVTVASPVPAVAADPDQFQQVLINLVLNACDACGAGGRVRLSASMDTGDTPGAWGMVRVDVEDNG
CGIAPRHVHQVFDPFFTTKKRGQGTGLGLTMVAHIVRNHGGRIELDSAPERGTRVTVRWPAAAPAGEERHVV

Sequences:

>Translated_712_residues
MSPLRPVFMRLPVLPVLLLCLMLSGVIAGVLHFMQRDRQALVDQMARERQAQLLEAVRGVSAALESAEEDLRFAGELLAQ
PGTAEEHRREMRALLEAVGQYKAILVFGTDGQERLRLVDRRSAAAMTHQFTAEDLALTVAQARSHPPGHVISSPPLPRAQ
SGWLRAFATALPEDAQDSGGVVVVLVDAEPRFAPLKLLASDSETQLLVLGVHGTPTALTHPNLADRYRRLDTDGHQTPGL
AALARALRAGESGTRIIERKEAARLGLGDSEVVATFSPVRFKNGAAWPVATLASTRVLRIHERGLVLRLSLAAVLVSGFL
IAFGVYVVLARSRAEALRDSQLHAQRLAHLHDKTQKILDNIPTGVLALSSTRHISAANRALSARMPADVVGQPLTAAFPQ
AQAPVIQRLEDLVHAATSDGRVRSLHGEPLCLFEEPGQYNVHAVPLEPNTPEVHTLVVIEDLSSLRALEGQLLRAEKLAT
VGVLAAGIAHEIGTPLGIVRGRAEYVQEKLGREHPQAAGLGTIVGQIDRVSRTLRQLLDFSRLRPADAQTVPLEPLVHSV
RELLWMEAERRRLKLEVTVASPVPAVAADPDQFQQVLINLVLNACDACGAGGRVRLSASMDTGDTPGAWGMVRVDVEDNG
CGIAPRHVHQVFDPFFTTKKRGQGTGLGLTMVAHIVRNHGGRIELDSAPERGTRVTVRWPAAAPAGEERHVV
>Mature_711_residues
SPLRPVFMRLPVLPVLLLCLMLSGVIAGVLHFMQRDRQALVDQMARERQAQLLEAVRGVSAALESAEEDLRFAGELLAQP
GTAEEHRREMRALLEAVGQYKAILVFGTDGQERLRLVDRRSAAAMTHQFTAEDLALTVAQARSHPPGHVISSPPLPRAQS
GWLRAFATALPEDAQDSGGVVVVLVDAEPRFAPLKLLASDSETQLLVLGVHGTPTALTHPNLADRYRRLDTDGHQTPGLA
ALARALRAGESGTRIIERKEAARLGLGDSEVVATFSPVRFKNGAAWPVATLASTRVLRIHERGLVLRLSLAAVLVSGFLI
AFGVYVVLARSRAEALRDSQLHAQRLAHLHDKTQKILDNIPTGVLALSSTRHISAANRALSARMPADVVGQPLTAAFPQA
QAPVIQRLEDLVHAATSDGRVRSLHGEPLCLFEEPGQYNVHAVPLEPNTPEVHTLVVIEDLSSLRALEGQLLRAEKLATV
GVLAAGIAHEIGTPLGIVRGRAEYVQEKLGREHPQAAGLGTIVGQIDRVSRTLRQLLDFSRLRPADAQTVPLEPLVHSVR
ELLWMEAERRRLKLEVTVASPVPAVAADPDQFQQVLINLVLNACDACGAGGRVRLSASMDTGDTPGAWGMVRVDVEDNGC
GIAPRHVHQVFDPFFTTKKRGQGTGLGLTMVAHIVRNHGGRIELDSAPERGTRVTVRWPAAAPAGEERHVV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=29.1005291005291, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=36.9294605809129, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786912, Length=463, Percent_Identity=25.2699784017279, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=30.0751879699248, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=30.1310043668122, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790300, Length=244, Percent_Identity=34.0163934426229, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI48994928, Length=377, Percent_Identity=25.4641909814324, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=262, Percent_Identity=25.9541984732824, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=29.5081967213115, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=30.2325581395349, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=347, Percent_Identity=22.7665706051873, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=27.3127753303965, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=218, Percent_Identity=27.0642201834862, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=27.8008298755187, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=25.4464285714286, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76942; Mature: 76810

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLRPVFMRLPVLPVLLLCLMLSGVIAGVLHFMQRDRQALVDQMARERQAQLLEAVRGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAALESAEEDLRFAGELLAQPGTAEEHRREMRALLEAVGQYKAILVFGTDGQERLRLVDR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
RSAAAMTHQFTAEDLALTVAQARSHPPGHVISSPPLPRAQSGWLRAFATALPEDAQDSGG
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
VVVVLVDAEPRFAPLKLLASDSETQLLVLGVHGTPTALTHPNLADRYRRLDTDGHQTPGL
EEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCH
AALARALRAGESGTRIIERKEAARLGLGDSEVVATFSPVRFKNGAAWPVATLASTRVLRI
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCEEECCCCCCHHHHHHHCCEEEE
HERGLVLRLSLAAVLVSGFLIAFGVYVVLARSRAEALRDSQLHAQRLAHLHDKTQKILDN
ECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPTGVLALSSTRHISAANRALSARMPADVVGQPLTAAFPQAQAPVIQRLEDLVHAATSDG
CCCCEEEECCCCHHHHHHHHHHHCCCHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCC
RVRSLHGEPLCLFEEPGQYNVHAVPLEPNTPEVHTLVVIEDLSSLRALEGQLLRAEKLAT
CEEEECCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
VGVLAAGIAHEIGTPLGIVRGRAEYVQEKLGREHPQAAGLGTIVGQIDRVSRTLRQLLDF
HHHHHHHHHHHHCCCHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SRLRPADAQTVPLEPLVHSVRELLWMEAERRRLKLEVTVASPVPAVAADPDQFQQVLINL
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCHHHHHHHHHHH
VLNACDACGAGGRVRLSASMDTGDTPGAWGMVRVDVEDNGCGIAPRHVHQVFDPFFTTKK
HHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
RGQGTGLGLTMVAHIVRNHGGRIELDSAPERGTRVTVRWPAAAPAGEERHVV
CCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SPLRPVFMRLPVLPVLLLCLMLSGVIAGVLHFMQRDRQALVDQMARERQAQLLEAVRGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAALESAEEDLRFAGELLAQPGTAEEHRREMRALLEAVGQYKAILVFGTDGQERLRLVDR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
RSAAAMTHQFTAEDLALTVAQARSHPPGHVISSPPLPRAQSGWLRAFATALPEDAQDSGG
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
VVVVLVDAEPRFAPLKLLASDSETQLLVLGVHGTPTALTHPNLADRYRRLDTDGHQTPGL
EEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCH
AALARALRAGESGTRIIERKEAARLGLGDSEVVATFSPVRFKNGAAWPVATLASTRVLRI
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCEEECCCCCCHHHHHHHCCEEEE
HERGLVLRLSLAAVLVSGFLIAFGVYVVLARSRAEALRDSQLHAQRLAHLHDKTQKILDN
ECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPTGVLALSSTRHISAANRALSARMPADVVGQPLTAAFPQAQAPVIQRLEDLVHAATSDG
CCCCEEEECCCCHHHHHHHHHHHCCCHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCC
RVRSLHGEPLCLFEEPGQYNVHAVPLEPNTPEVHTLVVIEDLSSLRALEGQLLRAEKLAT
CEEEECCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
VGVLAAGIAHEIGTPLGIVRGRAEYVQEKLGREHPQAAGLGTIVGQIDRVSRTLRQLLDF
HHHHHHHHHHHHCCCHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SRLRPADAQTVPLEPLVHSVRELLWMEAERRRLKLEVTVASPVPAVAADPDQFQQVLINL
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCHHHHHHHHHHH
VLNACDACGAGGRVRLSASMDTGDTPGAWGMVRVDVEDNGCGIAPRHVHQVFDPFFTTKK
HHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
RGQGTGLGLTMVAHIVRNHGGRIELDSAPERGTRVTVRWPAAAPAGEERHVV
CCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]