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The map label for this gene is zraR [H]

Identifier: 108757358

GI number: 108757358

Start: 5718474

End: 5719847

Strand: Direct

Name: zraR [H]

Synonym: MXAN_4580

Alternate gene names: 108757358

Gene position: 5718474-5719847 (Clockwise)

Preceding gene: 108763456

Following gene: 108760432

Centisome position: 62.57

GC content: 70.67

Gene sequence:

>1374_bases
ATGTCGTCTAGAGCCAGGGTCCTCGTCGTCGACGACCACGTCGAGATGGGGCAGATGTTGAAGGAACCGCTGACGGACGA
CGGCTACAAGGTCGACATCGCCACCGGCGGCGCGGATGCCATCGCCCAACTGCGCGCGCGCGTCTACGACGCGGTGCTGT
GCGACCTGCGCATGCAGGACGTGGACGGCTTCGACGTGCTCGACGCCGCGCGCAAGCTGGACCCGGACCTGCCCGTGGTG
ATGATGACGGCCTTCGGCGGCGTGGAGAGCGCCGTGGAGGCGATGAAGCGCGGCGCGTTCCACTACTTCACCAAGCCCTT
CCGGCTGGACGAGGTGCGCCTGTCACTTGAGCGCGCGCTGGAGCAGCGCCGCCTGCGCACCGAGCACCGCACGCTCAAGC
AGCAGGCCGCGGACCGTGGGGGCCTGGGCGCCCTGGTGGGCAGCAGCACCGCGATGCGCGACCTCTACGCGTTGATTGAG
CGGGTGGCCTGGTCCGGCGCCCCGGTGCTGGTGCGCGGCGAGAGCGGCAGTGGCAAGGAGCTGGTCGCCAGGGCTTTGCA
CTTCGAGGGCACCCGGCGCGCGGGGCCCTTCGTGGCCGTCAACTGCACCGCGCTGCCACACGCGCTTCTGGAGAGTGAGC
TGTTCGGCCACGTCAAAGGCGCCTTCACCGGCGCCACCACGGCCCGGCGTGGCCTCTTCGTGGAGGCGGACGGCGGCACG
CTGTTCCTGGACGAGATTGGCGACATGGCCCCCGAACTCCAGGCCCGGCTGCTCCGCGTGCTGGAGGACGGCGAGGTGCG
GGCCGTGGGCGCGGACGGCTCGCGCACGGTGGATGTGCGGGTGGTGGCCGCGACGCACCAGGACCTGGAGACGCGCGTCA
AGGAAGGCCGCTTCCGCGCGGACGTCTTCTACCGGCTCAACGTCGTCACGCTGCGGCTGCCGCCCCTGCGCGAGCGCCGC
GAGGACATCCCCGCGCTCATCGAGCACTTCCTCCAGCAAGCCAAGGCGCGCAATCCGCGCTCCGTCGTGCAGCGGTTCTC
CCCGGAGACGCTGGCAGCGCTGGGGGCCCTGCCCTGGGCGGGCAACGTGCGCGAGCTGGAGAACCTGGTGCAGCGGCTGG
TCGTGCTCGGCTCGACGGAGGTGGTGGATCTGCCGCAACTGCGCCCCCATTTGCCTTCGGACACCAGCCAGGAGAATCAC
CCGCTGGCCGCTGCACAGCGCACCATCGTTCCCCTGCGGCAGTTGGAGACGGAGTACATCGCCTGGGCCGTGGCCCGCTG
CGGGGGAAACAAGACGAAGGCGGCCGAGCTGCTCGGCATCGACGTCTCCACCATCCACCGGCGCGAGCGCGCGGAAGGCA
ATCCGCAACGCTGA

Upstream 100 bases:

>100_bases
CGCAACCACGGAGGCCGTATCGAACTGGACAGCGCGCCAGAGCGAGGCACCCGCGTCACCGTGCGCTGGCCCGCCGCGGC
ACCCGCCGGAGAGGAGCGAC

Downstream 100 bases:

>100_bases
CCTGGGCACGCTGCAACGGTGAGCGGGCCACAGTTGGGGTGTCTCAGAGGGATGGGGGCGCGGCACGGGGCTTGAAAATG
ACAGGAGGCATGAACCGAAC

Product: sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSSRARVLVVDDHVEMGQMLKEPLTDDGYKVDIATGGADAIAQLRARVYDAVLCDLRMQDVDGFDVLDAARKLDPDLPVV
MMTAFGGVESAVEAMKRGAFHYFTKPFRLDEVRLSLERALEQRRLRTEHRTLKQQAADRGGLGALVGSSTAMRDLYALIE
RVAWSGAPVLVRGESGSGKELVARALHFEGTRRAGPFVAVNCTALPHALLESELFGHVKGAFTGATTARRGLFVEADGGT
LFLDEIGDMAPELQARLLRVLEDGEVRAVGADGSRTVDVRVVAATHQDLETRVKEGRFRADVFYRLNVVTLRLPPLRERR
EDIPALIEHFLQQAKARNPRSVVQRFSPETLAALGALPWAGNVRELENLVQRLVVLGSTEVVDLPQLRPHLPSDTSQENH
PLAAAQRTIVPLRQLETEYIAWAVARCGGNKTKAAELLGIDVSTIHRRERAEGNPQR

Sequences:

>Translated_457_residues
MSSRARVLVVDDHVEMGQMLKEPLTDDGYKVDIATGGADAIAQLRARVYDAVLCDLRMQDVDGFDVLDAARKLDPDLPVV
MMTAFGGVESAVEAMKRGAFHYFTKPFRLDEVRLSLERALEQRRLRTEHRTLKQQAADRGGLGALVGSSTAMRDLYALIE
RVAWSGAPVLVRGESGSGKELVARALHFEGTRRAGPFVAVNCTALPHALLESELFGHVKGAFTGATTARRGLFVEADGGT
LFLDEIGDMAPELQARLLRVLEDGEVRAVGADGSRTVDVRVVAATHQDLETRVKEGRFRADVFYRLNVVTLRLPPLRERR
EDIPALIEHFLQQAKARNPRSVVQRFSPETLAALGALPWAGNVRELENLVQRLVVLGSTEVVDLPQLRPHLPSDTSQENH
PLAAAQRTIVPLRQLETEYIAWAVARCGGNKTKAAELLGIDVSTIHRRERAEGNPQR
>Mature_456_residues
SSRARVLVVDDHVEMGQMLKEPLTDDGYKVDIATGGADAIAQLRARVYDAVLCDLRMQDVDGFDVLDAARKLDPDLPVVM
MTAFGGVESAVEAMKRGAFHYFTKPFRLDEVRLSLERALEQRRLRTEHRTLKQQAADRGGLGALVGSSTAMRDLYALIER
VAWSGAPVLVRGESGSGKELVARALHFEGTRRAGPFVAVNCTALPHALLESELFGHVKGAFTGATTARRGLFVEADGGTL
FLDEIGDMAPELQARLLRVLEDGEVRAVGADGSRTVDVRVVAATHQDLETRVKEGRFRADVFYRLNVVTLRLPPLRERRE
DIPALIEHFLQQAKARNPRSVVQRFSPETLAALGALPWAGNVRELENLVQRLVVLGSTEVVDLPQLRPHLPSDTSQENHP
LAAAQRTIVPLRQLETEYIAWAVARCGGNKTKAAELLGIDVSTIHRRERAEGNPQR

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=439, Percent_Identity=47.380410022779, Blast_Score=377, Evalue=1e-105,
Organism=Escherichia coli, GI1788550, Length=444, Percent_Identity=43.2432432432432, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1790299, Length=470, Percent_Identity=42.1276595744681, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1788905, Length=444, Percent_Identity=39.6396396396396, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=44.1358024691358, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI87082117, Length=265, Percent_Identity=50.188679245283, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789087, Length=264, Percent_Identity=45.4545454545455, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786524, Length=357, Percent_Identity=42.0168067226891, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI87082152, Length=311, Percent_Identity=44.3729903536978, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87081872, Length=312, Percent_Identity=39.1025641025641, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787583, Length=245, Percent_Identity=40.4081632653061, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1789828, Length=236, Percent_Identity=39.8305084745763, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081858, Length=302, Percent_Identity=34.7682119205298, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=107, Percent_Identity=30.8411214953271, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789402, Length=112, Percent_Identity=35.7142857142857, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787375, Length=107, Percent_Identity=35.5140186915888, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50330; Mature: 50199

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRARVLVVDDHVEMGQMLKEPLTDDGYKVDIATGGADAIAQLRARVYDAVLCDLRMQD
CCCCCEEEEEECCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
VDGFDVLDAARKLDPDLPVVMMTAFGGVESAVEAMKRGAFHYFTKPFRLDEVRLSLERAL
CCCHHHHHHHHHCCCCCCEEEEEHHCCHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHH
EQRRLRTEHRTLKQQAADRGGLGALVGSSTAMRDLYALIERVAWSGAPVLVRGESGSGKE
HHHHHHHHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
LVARALHFEGTRRAGPFVAVNCTALPHALLESELFGHVKGAFTGATTARRGLFVEADGGT
HHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCE
LFLDEIGDMAPELQARLLRVLEDGEVRAVGADGSRTVDVRVVAATHQDLETRVKEGRFRA
EEHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEECHHHHHHHHHCCCEEE
DVFYRLNVVTLRLPPLRERREDIPALIEHFLQQAKARNPRSVVQRFSPETLAALGALPWA
EEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCC
GNVRELENLVQRLVVLGSTEVVDLPQLRPHLPSDTSQENHPLAAAQRTIVPLRQLETEYI
CCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AWAVARCGGNKTKAAELLGIDVSTIHRRERAEGNPQR
HHHHHHCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSRARVLVVDDHVEMGQMLKEPLTDDGYKVDIATGGADAIAQLRARVYDAVLCDLRMQD
CCCCEEEEEECCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
VDGFDVLDAARKLDPDLPVVMMTAFGGVESAVEAMKRGAFHYFTKPFRLDEVRLSLERAL
CCCHHHHHHHHHCCCCCCEEEEEHHCCHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHH
EQRRLRTEHRTLKQQAADRGGLGALVGSSTAMRDLYALIERVAWSGAPVLVRGESGSGKE
HHHHHHHHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
LVARALHFEGTRRAGPFVAVNCTALPHALLESELFGHVKGAFTGATTARRGLFVEADGGT
HHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCE
LFLDEIGDMAPELQARLLRVLEDGEVRAVGADGSRTVDVRVVAATHQDLETRVKEGRFRA
EEHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEECHHHHHHHHHCCCEEE
DVFYRLNVVTLRLPPLRERREDIPALIEHFLQQAKARNPRSVVQRFSPETLAALGALPWA
EEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCC
GNVRELENLVQRLVVLGSTEVVDLPQLRPHLPSDTSQENHPLAAAQRTIVPLRQLETEYI
CCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AWAVARCGGNKTKAAELLGIDVSTIHRRERAEGNPQR
HHHHHHCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]