Click here to switch to the map view.

The map label for this gene is slyD [H]

Identifier: 108762879

GI number: 108762879

Start: 4604419

End: 4604901

Strand: Reverse

Name: slyD [H]

Synonym: MXAN_3831

Alternate gene names: 108762879

Gene position: 4604901-4604419 (Counterclockwise)

Preceding gene: 108758332

Following gene: 108758168

Centisome position: 50.38

GC content: 66.87

Gene sequence:

>483_bases
ATGAAAATTACCAAGGACAGCGTCGTCTCCATCGATTTCCGCCTCCACCTCGGCGACGGCAAGGCCGTGGACGAGAGCGA
GCCGGGGGAGCCGCTCGTCTATCTGCAGGGGCACGAGGAAATCGTCCCGGGCCTGGAAAAGGCGCTTGAGGGCAAGTCGC
GTGGTGACACCCTCCAGGTGACGGTGGGTCCCGACGAGGGCTACGGCGACTATGACCCGGAAGGCATCGAGGAAGTCCCG
AAGACGGAGTTCCCGGAGGGCCTGGAGCTGGTGGCGGGCGGCGTGCTCAGCGCCACCGACCCGGACGGGGACGAGGTGGA
CTTCTTCATCAAGGAAGTGAAGGCCGACTCCGTGCTGGTGGACTTCAACCACCCGCTGGCCGGCAAGACGCTGCACTTCG
AGGTCACCGTGCGGGACGTCCGCGCCGCGACGGCCGAGGAGCTGGAGCACGGCCACGCCCACGGGCCCCACGACTCTCAC
TGA

Upstream 100 bases:

>100_bases
CCACTGGAATCGGACAGTCGATCCGGGCGGGACGCTCGCCTCATTGTCAGACAGGCACATGATTGAGGCACACGCCACGG
CCGTGCGCTATGAGGGCCCC

Downstream 100 bases:

>100_bases
TTCGGACGGGCGCCTTCGCGGGCCCCTCCTTGCTTCGACGCCGGGCGTCCCCAAGACAGGACGCCCGGCGGAAGTCCTCC
GCCTAGCCGCCCAGGAAGTC

Product: FKBP-type peptidylprolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKITKDSVVSIDFRLHLGDGKAVDESEPGEPLVYLQGHEEIVPGLEKALEGKSRGDTLQVTVGPDEGYGDYDPEGIEEVP
KTEFPEGLELVAGGVLSATDPDGDEVDFFIKEVKADSVLVDFNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPHDSH

Sequences:

>Translated_160_residues
MKITKDSVVSIDFRLHLGDGKAVDESEPGEPLVYLQGHEEIVPGLEKALEGKSRGDTLQVTVGPDEGYGDYDPEGIEEVP
KTEFPEGLELVAGGVLSATDPDGDEVDFFIKEVKADSVLVDFNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPHDSH
>Mature_160_residues
MKITKDSVVSIDFRLHLGDGKAVDESEPGEPLVYLQGHEEIVPGLEKALEGKSRGDTLQVTVGPDEGYGDYDPEGIEEVP
KTEFPEGLELVAGGVLSATDPDGDEVDFFIKEVKADSVLVDFNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPHDSH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=43.2432432432432, Blast_Score=103, Evalue=4e-24,
Organism=Escherichia coli, GI1786211, Length=143, Percent_Identity=33.5664335664336, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17291; Mature: 17291

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITKDSVVSIDFRLHLGDGKAVDESEPGEPLVYLQGHEEIVPGLEKALEGKSRGDTLQV
CCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEE
TVGPDEGYGDYDPEGIEEVPKTEFPEGLELVAGGVLSATDPDGDEVDFFIKEVKADSVLV
EECCCCCCCCCCCCHHHHCCCCCCCCCHHHHHCCEEECCCCCCCHHHHHHHHCCCCEEEE
DFNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPHDSH
ECCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKITKDSVVSIDFRLHLGDGKAVDESEPGEPLVYLQGHEEIVPGLEKALEGKSRGDTLQV
CCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEE
TVGPDEGYGDYDPEGIEEVPKTEFPEGLELVAGGVLSATDPDGDEVDFFIKEVKADSVLV
EECCCCCCCCCCCCHHHHCCCCCCCCCHHHHHCCEEECCCCCCCHHHHHHHHCCCCEEEE
DFNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPHDSH
ECCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]