Click here to switch to the map view.

The map label for this gene is yngHB [H]

Identifier: 108762374

GI number: 108762374

Start: 6948792

End: 6949004

Strand: Reverse

Name: yngHB [H]

Synonym: MXAN_5594

Alternate gene names: 108762374

Gene position: 6949004-6948792 (Counterclockwise)

Preceding gene: 108758762

Following gene: 108763786

Centisome position: 76.03

GC content: 62.91

Gene sequence:

>213_bases
ATGGCGGACGTAGCGGCGCACATCACCGGCACGGTGTGGAAGATTGAGGTTCAGGTCGGCCAGCAGGTCAACGCGGGCGA
CACGCTCGTCATCCTCGAATCCATGAAGATGGAGATGCCCGTGGAGGCAGAGGATGGCGGGACGGTGAAGGAGATTCGGG
TGAAGGAGGCGCAGTCGGTCAACGAGGGCGATGTCCTCGTGGTGCTCGGCTAG

Upstream 100 bases:

>100_bases
CCAGGCCGGCGAGCTGGACACGAACTTCCTGGAGCACCACGCCAAGCCGGCGTAGCGGGGCCCGCTCCAGCCCCAACCAC
CCCTGAGGAGGCACGGATTC

Downstream 100 bases:

>100_bases
CAGTGGAGCCCGTCGTCGCGACAGGTGCTTCGCTGAACGTCGAGGACCGCGACGACGGGGTCCGGGTGTTGACGCTGTCC
AACCCGGCTCGCCGCAACGC

Product: biotin/lipoic acid binding domain-containing protein

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BLAP [H]

Number of amino acids: Translated: 70; Mature: 69

Protein sequence:

>70_residues
MADVAAHITGTVWKIEVQVGQQVNAGDTLVILESMKMEMPVEAEDGGTVKEIRVKEAQSVNEGDVLVVLG

Sequences:

>Translated_70_residues
MADVAAHITGTVWKIEVQVGQQVNAGDTLVILESMKMEMPVEAEDGGTVKEIRVKEAQSVNEGDVLVVLG
>Mature_69_residues
ADVAAHITGTVWKIEVQVGQQVNAGDTLVILESMKMEMPVEAEDGGTVKEIRVKEAQSVNEGDVLVVLG

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 7465; Mature: 7333

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVAAHITGTVWKIEVQVGQQVNAGDTLVILESMKMEMPVEAEDGGTVKEIRVKEAQSV
CCCCCCEECCEEEEEEEEECCCCCCCCEEEEEECCCCCCCEECCCCCCEEEEEECCCCCC
NEGDVLVVLG
CCCCEEEEEC
>Mature Secondary Structure 
ADVAAHITGTVWKIEVQVGQQVNAGDTLVILESMKMEMPVEAEDGGTVKEIRVKEAQSV
CCCCCEECCEEEEEEEEECCCCCCCCEEEEEECCCCCCCEECCCCCCEEEEEECCCCCC
NEGDVLVVLG
CCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10557314; 9384377 [H]