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The map label for this gene is murB

Identifier: 108762211

GI number: 108762211

Start: 6964122

End: 6965054

Strand: Reverse

Name: murB

Synonym: MXAN_5602

Alternate gene names: 108762211

Gene position: 6965054-6964122 (Counterclockwise)

Preceding gene: 108759161

Following gene: 108760939

Centisome position: 76.21

GC content: 69.99

Gene sequence:

>933_bases
ATGGTGGAAGCAGGCGTGAAGACGGCGCTGGCGGCTCGCGTGGAGTCGCTGGGCGGCTGCGAGGTGAAGGCGGGCGAACC
GCTGGCGCCTCTCACCAGCGTCCGGGCCGGCGGCGCCGCGGAAGCCCTGGTGCGCCCGCGTTCGCCAGACGCCCTGGTGG
CGCTGCTGAAGCTGGCGCGTGAAGAGGGTGTCCCCGTTTCGATTCTGGGCGGCGGCGCCAACACGCTGGTGGGCGACGGC
GGGGTGCCCGGCCTGACGCTGAAGCTGCCAGGAGACCTCTTTCCGGAGGTGGCCGACGTGGGCCCCGAGGAAGGGCGGCT
CACCCTGGGGGCGGGGGCGGCCATCGTCCGCCTCATCAATGTCATGCGGGCCCACGCGCTGGTGGGCGCGGAGTTCCTGG
CCGGCATCCCCGGCACGCTGGGCGGCGCGGTGTCGATGAACGCCGGCACCAAGAACGGCGAAGCCTTTCGCGTCATCGAG
GCGGTGGAAGTGGCCACGGCGGACGGGGTGGGGTGGCTGACGAAGGCACAGGTGCCGTATTCCTACCGTCACTCCGAATT
GCCGCCGGGCGGCGTCGTCACCCGGGTGCGTTTCGCGCTGCGCAAGGGGGACGTGGTGGCCTCCAAGGCCGTCATGGACG
CTGACCTGGGTTACCGGAAACGGACACAGCCGCTCAGTCAGCCCAACTTCGGCAGCGTCTTCACCAACCCGCCGGGCGAC
CATGCCGGACGGCTCATTGAACTGGCGGGCCTGAAAGGGTACTCGCTGGGGCGCGCGCAGGTGTCCACCCTGCACGCCAA
CTGGATTGTGAACCTGGGCGGTGCCACCGCCCGCGACGTGCTGGGACTCGTCACCCTCATGCAGCAGCGGGTGCTCGAGC
AGTCCGGCGTTGACATGAAACCCGAAGTCAAGCGCCTGGGAGACTTCCTGTGA

Upstream 100 bases:

>100_bases
GGTGACCTGGTGCTGACGCTGGGAGCGGGTGACATCACCCACGTGGGGCCGGAGTTGCTCGAGCTGCTTCGCACCACCCC
CCTGGCGAAGGACTAGCGCC

Downstream 100 bases:

>100_bases
CTCCGAACCGCGGTGCCTTCACGAAGGACGAGCTCAAGCAGAAGCGTGTCGGTGTACTGTTGGGCGGAATGTCCGCGGAG
CGCGACGTGTCCCTGCGCAC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVEAGVKTALAARVESLGGCEVKAGEPLAPLTSVRAGGAAEALVRPRSPDALVALLKLAREEGVPVSILGGGANTLVGDG
GVPGLTLKLPGDLFPEVADVGPEEGRLTLGAGAAIVRLINVMRAHALVGAEFLAGIPGTLGGAVSMNAGTKNGEAFRVIE
AVEVATADGVGWLTKAQVPYSYRHSELPPGGVVTRVRFALRKGDVVASKAVMDADLGYRKRTQPLSQPNFGSVFTNPPGD
HAGRLIELAGLKGYSLGRAQVSTLHANWIVNLGGATARDVLGLVTLMQQRVLEQSGVDMKPEVKRLGDFL

Sequences:

>Translated_310_residues
MVEAGVKTALAARVESLGGCEVKAGEPLAPLTSVRAGGAAEALVRPRSPDALVALLKLAREEGVPVSILGGGANTLVGDG
GVPGLTLKLPGDLFPEVADVGPEEGRLTLGAGAAIVRLINVMRAHALVGAEFLAGIPGTLGGAVSMNAGTKNGEAFRVIE
AVEVATADGVGWLTKAQVPYSYRHSELPPGGVVTRVRFALRKGDVVASKAVMDADLGYRKRTQPLSQPNFGSVFTNPPGD
HAGRLIELAGLKGYSLGRAQVSTLHANWIVNLGGATARDVLGLVTLMQQRVLEQSGVDMKPEVKRLGDFL
>Mature_310_residues
MVEAGVKTALAARVESLGGCEVKAGEPLAPLTSVRAGGAAEALVRPRSPDALVALLKLAREEGVPVSILGGGANTLVGDG
GVPGLTLKLPGDLFPEVADVGPEEGRLTLGAGAAIVRLINVMRAHALVGAEFLAGIPGTLGGAVSMNAGTKNGEAFRVIE
AVEVATADGVGWLTKAQVPYSYRHSELPPGGVVTRVRFALRKGDVVASKAVMDADLGYRKRTQPLSQPNFGSVFTNPPGD
HAGRLIELAGLKGYSLGRAQVSTLHANWIVNLGGATARDVLGLVTLMQQRVLEQSGVDMKPEVKRLGDFL

Specific function: Cell wall formation

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURB_MYXXD (Q1D0T2)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633741.1
- ProteinModelPortal:   Q1D0T2
- SMR:   Q1D0T2
- STRING:   Q1D0T2
- GeneID:   4105957
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_5602
- TIGR:   MXAN_5602
- eggNOG:   COG0812
- HOGENOM:   HBG686573
- OMA:   ILIVPKH
- ProtClustDB:   PRK14652
- BioCyc:   MXAN246197:MXAN_5602-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00037
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094
- Gene3D:   G3DSA:3.30.465.10
- Gene3D:   G3DSA:3.30.43.10
- Gene3D:   G3DSA:3.90.78.10
- PANTHER:   PTHR21071
- TIGRFAMs:   TIGR00179

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C; SSF56176 FAD-binding_2; SSF56194 MurB_C

EC number: =1.1.1.158

Molecular weight: Translated: 31972; Mature: 31972

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS51387 FAD_PCMH

Important sites: ACT_SITE 183-183 ACT_SITE 232-232 ACT_SITE 302-302

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEAGVKTALAARVESLGGCEVKAGEPLAPLTSVRAGGAAEALVRPRSPDALVALLKLAR
CCCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHCCCCCHHHHCCCCCCHHHHHHHHHHH
EEGVPVSILGGGANTLVGDGGVPGLTLKLPGDLFPEVADVGPEEGRLTLGAGAAIVRLIN
HCCCCEEEECCCCCEEECCCCCCEEEEECCCHHCCHHHHCCCCCCEEEECCHHHHHHHHH
VMRAHALVGAEFLAGIPGTLGGAVSMNAGTKNGEAFRVIEAVEVATADGVGWLTKAQVPY
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHCCCCCCCEEECCCCC
SYRHSELPPGGVVTRVRFALRKGDVVASKAVMDADLGYRKRTQPLSQPNFGSVFTNPPGD
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCC
HAGRLIELAGLKGYSLGRAQVSTLHANWIVNLGGATARDVLGLVTLMQQRVLEQSGVDMK
HHCCEEEEECCCCCCCCCHHHEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PEVKRLGDFL
HHHHHHCCCC
>Mature Secondary Structure
MVEAGVKTALAARVESLGGCEVKAGEPLAPLTSVRAGGAAEALVRPRSPDALVALLKLAR
CCCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHCCCCCHHHHCCCCCCHHHHHHHHHHH
EEGVPVSILGGGANTLVGDGGVPGLTLKLPGDLFPEVADVGPEEGRLTLGAGAAIVRLIN
HCCCCEEEECCCCCEEECCCCCCEEEEECCCHHCCHHHHCCCCCCEEEECCHHHHHHHHH
VMRAHALVGAEFLAGIPGTLGGAVSMNAGTKNGEAFRVIEAVEVATADGVGWLTKAQVPY
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHCCCCCCCEEECCCCC
SYRHSELPPGGVVTRVRFALRKGDVVASKAVMDADLGYRKRTQPLSQPNFGSVFTNPPGD
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCC
HAGRLIELAGLKGYSLGRAQVSTLHANWIVNLGGATARDVLGLVTLMQQRVLEQSGVDMK
HHCCEEEEECCCCCCCCCHHHEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PEVKRLGDFL
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA