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The map label for this gene is carA [H]

Identifier: 108762105

GI number: 108762105

Start: 4092162

End: 4093286

Strand: Direct

Name: carA [H]

Synonym: MXAN_3512

Alternate gene names: 108762105

Gene position: 4092162-4093286 (Clockwise)

Preceding gene: 108762395

Following gene: 108757411

Centisome position: 44.77

GC content: 68.62

Gene sequence:

>1125_bases
ATGACGAAGCGGGCAGTGCTCGCCCTGGCGGATGGCACCACGTTCGAAGGCCGTGCGTTTGGCGCGGTGGGCGAAACGGT
GGGTGAAGTGGTGTTCAACACGACCATGTACGGTTACCAGGAGGTCCTCACGGACCCCTCGTACGTGGGCCAGATTGTCA
CCATGTCGTACCCGGAGATTGGCAACGTCGGCGCCAACCCGGAGGACGAGGAGGGCTCCCGGGTGCACGCGGTGGGCATG
GTGGTGCGCGCCCTCAGCGAGCAGCCGTCCAACTGGCGCGCGAAGGAGTCGCTGGACGCGTACCTGAAGCGCAACGGCGT
CGCCGGCATCGAGGGCATCGACACCCGCCGCCTGGTGCGCCACCTGCGCACGCATGGCGCGCAGATGGGCGTCATCTCCA
GCGAGGGCCTGTCCCCCCTGGCCCTGGTGGAGCGTGCCCGCTCCGCGCGCGGCATGGAGGGCCTGGACCTGGCCACGGGC
GTGTCCACGAAGGAGGCCTACACCTTCACCCAGCCCTCGCCGGACGTCTTCACCGGCTTGGGAGAGGTGCGGGTGCCGGC
CGAGCCCCGCTTCGACGTGGTGGCCTATGACTACGGTCTGAAGAAGTCGATGCTGCACTTCCTGGTGGATGTGGGCTGCC
GCGTGACGGTGGTGCCGGCCAACACCTCGGCGGAAGAGGTGCTGGCGCGCAAGCCGAACGGCGTCTTCCTGGCCAACGGC
CCTGGAGATCCGGCGGCGGTGAAGGGCGCGGACCGCACCGTGGCGGCGCTGCTGGGCAAGGTGCCGGTGTTCGGCATCTG
CCTGGGGCATCAAATCATGGCGCTGGCCCTGGGCGGCCGGACGTACAAGATGAAGTTTGGCCACCGGGGCGGAAACCAGC
CGGTGAAGGACCTCACGACGGGCAAGGTGGAAATCACCGCGCAGAACCACGGCTTCGCCGTGGATGACGCCAGCCTCAAG
GGCCTGGCCGTCGTAACGCACATCAACCTCAACGACGGCACGGTGGAGGGCCTGGCCGTCCCGGACGCGCGGGCCTTCAG
CGTGCAGTACCACCCCGAGGCCTCGCCCGGCCCCCATGACGCGCGCTATCTCTTCGACAGGTTCGCGAAGCTGATGGCGG
GGTAG

Upstream 100 bases:

>100_bases
TCCATGGCCGGAAGCAGAAGGGTCGCGTTATCCAGACGTGGGTCGCGGGCCACAAGGTGTTCGACAAGGGCCAGGTCGGC
CAGAGCAAGGAGTCGCGGTG

Downstream 100 bases:

>100_bases
GATGGCGCCACCGAATATGACCTCGTCGCTGTCACCGCTCTCCTATCAGCCGTATCTGGATCTGCTCATCGCCTTTGGCA
GTGCCGAGCCGCGCAAGGAG

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTKRAVLALADGTTFEGRAFGAVGETVGEVVFNTTMYGYQEVLTDPSYVGQIVTMSYPEIGNVGANPEDEEGSRVHAVGM
VVRALSEQPSNWRAKESLDAYLKRNGVAGIEGIDTRRLVRHLRTHGAQMGVISSEGLSPLALVERARSARGMEGLDLATG
VSTKEAYTFTQPSPDVFTGLGEVRVPAEPRFDVVAYDYGLKKSMLHFLVDVGCRVTVVPANTSAEEVLARKPNGVFLANG
PGDPAAVKGADRTVAALLGKVPVFGICLGHQIMALALGGRTYKMKFGHRGGNQPVKDLTTGKVEITAQNHGFAVDDASLK
GLAVVTHINLNDGTVEGLAVPDARAFSVQYHPEASPGPHDARYLFDRFAKLMAG

Sequences:

>Translated_374_residues
MTKRAVLALADGTTFEGRAFGAVGETVGEVVFNTTMYGYQEVLTDPSYVGQIVTMSYPEIGNVGANPEDEEGSRVHAVGM
VVRALSEQPSNWRAKESLDAYLKRNGVAGIEGIDTRRLVRHLRTHGAQMGVISSEGLSPLALVERARSARGMEGLDLATG
VSTKEAYTFTQPSPDVFTGLGEVRVPAEPRFDVVAYDYGLKKSMLHFLVDVGCRVTVVPANTSAEEVLARKPNGVFLANG
PGDPAAVKGADRTVAALLGKVPVFGICLGHQIMALALGGRTYKMKFGHRGGNQPVKDLTTGKVEITAQNHGFAVDDASLK
GLAVVTHINLNDGTVEGLAVPDARAFSVQYHPEASPGPHDARYLFDRFAKLMAG
>Mature_373_residues
TKRAVLALADGTTFEGRAFGAVGETVGEVVFNTTMYGYQEVLTDPSYVGQIVTMSYPEIGNVGANPEDEEGSRVHAVGMV
VRALSEQPSNWRAKESLDAYLKRNGVAGIEGIDTRRLVRHLRTHGAQMGVISSEGLSPLALVERARSARGMEGLDLATGV
STKEAYTFTQPSPDVFTGLGEVRVPAEPRFDVVAYDYGLKKSMLHFLVDVGCRVTVVPANTSAEEVLARKPNGVFLANGP
GDPAAVKGADRTVAALLGKVPVFGICLGHQIMALALGGRTYKMKFGHRGGNQPVKDLTTGKVEITAQNHGFAVDDASLKG
LAVVTHINLNDGTVEGLAVPDARAFSVQYHPEASPGPHDARYLFDRFAKLMAG

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=376, Percent_Identity=40.4255319148936, Blast_Score=261, Evalue=7e-70,
Organism=Homo sapiens, GI21361331, Length=384, Percent_Identity=36.71875, Blast_Score=221, Evalue=6e-58,
Organism=Homo sapiens, GI169790915, Length=384, Percent_Identity=36.71875, Blast_Score=221, Evalue=6e-58,
Organism=Escherichia coli, GI1786215, Length=374, Percent_Identity=56.4171122994652, Blast_Score=407, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI193204318, Length=380, Percent_Identity=37.6315789473684, Blast_Score=240, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6324878, Length=381, Percent_Identity=38.5826771653543, Blast_Score=257, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6322331, Length=387, Percent_Identity=36.1757105943152, Blast_Score=245, Evalue=9e-66,
Organism=Drosophila melanogaster, GI45555749, Length=389, Percent_Identity=39.0745501285347, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24642586, Length=389, Percent_Identity=39.0745501285347, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 39824; Mature: 39693

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRAVLALADGTTFEGRAFGAVGETVGEVVFNTTMYGYQEVLTDPSYVGQIVTMSYPEI
CCCCEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCC
GNVGANPEDEEGSRVHAVGMVVRALSEQPSNWRAKESLDAYLKRNGVAGIEGIDTRRLVR
CCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
HLRTHGAQMGVISSEGLSPLALVERARSARGMEGLDLATGVSTKEAYTFTQPSPDVFTGL
HHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEECCCCCHHHHCC
GEVRVPAEPRFDVVAYDYGLKKSMLHFLVDVGCRVTVVPANTSAEEVLARKPNGVFLANG
CCEECCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCEEEECC
PGDPAAVKGADRTVAALLGKVPVFGICLGHQIMALALGGRTYKMKFGHRGGNQPVKDLTT
CCCCCEECCCCHHHHHHHCCCCCEEHHHHHHEEHHEECCEEEEEEECCCCCCCCHHHCCC
GKVEITAQNHGFAVDDASLKGLAVVTHINLNDGTVEGLAVPDARAFSVQYHPEASPGPHD
CEEEEEECCCCEEECCCCCCCEEEEEEEECCCCCCCEEECCCCEEEEEEECCCCCCCCCH
ARYLFDRFAKLMAG
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TKRAVLALADGTTFEGRAFGAVGETVGEVVFNTTMYGYQEVLTDPSYVGQIVTMSYPEI
CCCEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCC
GNVGANPEDEEGSRVHAVGMVVRALSEQPSNWRAKESLDAYLKRNGVAGIEGIDTRRLVR
CCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
HLRTHGAQMGVISSEGLSPLALVERARSARGMEGLDLATGVSTKEAYTFTQPSPDVFTGL
HHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEECCCCCHHHHCC
GEVRVPAEPRFDVVAYDYGLKKSMLHFLVDVGCRVTVVPANTSAEEVLARKPNGVFLANG
CCEECCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCEEEECC
PGDPAAVKGADRTVAALLGKVPVFGICLGHQIMALALGGRTYKMKFGHRGGNQPVKDLTT
CCCCCEECCCCHHHHHHHCCCCCEEHHHHHHEEHHEECCEEEEEEECCCCCCCCHHHCCC
GKVEITAQNHGFAVDDASLKGLAVVTHINLNDGTVEGLAVPDARAFSVQYHPEASPGPHD
CEEEEEECCCCEEECCCCCCCEEEEEEEECCCCCCCEEECCCCEEEEEEECCCCCCCCCH
ARYLFDRFAKLMAG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA