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The map label for this gene is grsT [H]

Identifier: 108758138

GI number: 108758138

Start: 4067161

End: 4067973

Strand: Reverse

Name: grsT [H]

Synonym: MXAN_3486

Alternate gene names: 108758138

Gene position: 4067973-4067161 (Counterclockwise)

Preceding gene: 108763067

Following gene: 108760299

Centisome position: 44.51

GC content: 70.73

Gene sequence:

>813_bases
GTGGCCATGCGACAGAGCCTTCACGTCATGCAAAGCGCGTCCAACTCGAGCCCTCATGCCCCCGACCGCTGGTTCCCCAC
CCGGAAGCCGTTGACGGACCCACGGCTGCGGCTGTTCTGTCTGCCGTACGCCGGTGGCAGCGTGGCCATCTACAACCAGT
GGAGCCAGGGCCTGCCGGCGGGTGTGGAGCTGTGCCCCGTCCAGCTTCCCGGGCGCGAACGCCGCCTGTCCGAGAAGCCC
ATTGGCAGCCTGCCTGCCCTGGTGGACGCGCTGCTGCCCGCCATCGCGCCGCTGCTGGACCGGCCCTTCGCCTTCTTCGG
CTACAGCATGGGCGCTCGCATCTCCCTGGAGCTCGCCAGGCGCCTCCAGGCTCGCAATGGCCCGCGCCCCGTGGGCCTGT
TCCTGGGGGCCGCCGGGCCGCCGTCCGTCAACACCCGCGAGCCCATCCACCATCTGCCCGAACCGGAGTTCATCGCGCAA
CTGCGGCGCTATGACGGCACGCCCGAGGAGATCTTCCAGCACCGCGAGCTGCTGGAGCTGGTGCTGCCCATGCTGCGCGC
CGACTTCGGCATCGCCTTCACGGAGGACGGCCCCCAGCCCGCGAAGCTGGAGGTCCCCATCTCCGTCGTCGGCTCGCCCG
AGGACAAGCACGTCCCCACCGCGAACCTGGAGCGCTGGCGCGACGAGACGCGGAGCGAGGACGTCCGCGTCCGCCTCTTC
CCCGGCGGCCACTTCTTCATCAAGTCGCAGCGGGACGCCCTCCTCGCGCACATCAGCGAGGACCTGAACCGGTGGATGGG
CCGCGCGCCCTGA

Upstream 100 bases:

>100_bases
GAAGCCCGCGGAACGCCCCATTGTGACTCCAGAACGACGCCCCTGCGCGTCCCCGAAACGCTAACACGCCACGCGGCCTC
CGGGACTTGACCCGTTTTCC

Downstream 100 bases:

>100_bases
GCCCGCCGTCTACGCCGCCTGGAACCGGGGCGGCGTGTCCCCGGCCAGCGGCACCGTGAACTGCCAACGCACCGACAGCG
GCTGCCCACGGGGCCGGTTC

Product: thioesterase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAMRQSLHVMQSASNSSPHAPDRWFPTRKPLTDPRLRLFCLPYAGGSVAIYNQWSQGLPAGVELCPVQLPGRERRLSEKP
IGSLPALVDALLPAIAPLLDRPFAFFGYSMGARISLELARRLQARNGPRPVGLFLGAAGPPSVNTREPIHHLPEPEFIAQ
LRRYDGTPEEIFQHRELLELVLPMLRADFGIAFTEDGPQPAKLEVPISVVGSPEDKHVPTANLERWRDETRSEDVRVRLF
PGGHFFIKSQRDALLAHISEDLNRWMGRAP

Sequences:

>Translated_270_residues
MAMRQSLHVMQSASNSSPHAPDRWFPTRKPLTDPRLRLFCLPYAGGSVAIYNQWSQGLPAGVELCPVQLPGRERRLSEKP
IGSLPALVDALLPAIAPLLDRPFAFFGYSMGARISLELARRLQARNGPRPVGLFLGAAGPPSVNTREPIHHLPEPEFIAQ
LRRYDGTPEEIFQHRELLELVLPMLRADFGIAFTEDGPQPAKLEVPISVVGSPEDKHVPTANLERWRDETRSEDVRVRLF
PGGHFFIKSQRDALLAHISEDLNRWMGRAP
>Mature_269_residues
AMRQSLHVMQSASNSSPHAPDRWFPTRKPLTDPRLRLFCLPYAGGSVAIYNQWSQGLPAGVELCPVQLPGRERRLSEKPI
GSLPALVDALLPAIAPLLDRPFAFFGYSMGARISLELARRLQARNGPRPVGLFLGAAGPPSVNTREPIHHLPEPEFIAQL
RRYDGTPEEIFQHRELLELVLPMLRADFGIAFTEDGPQPAKLEVPISVVGSPEDKHVPTANLERWRDETRSEDVRVRLFP
GGHFFIKSQRDALLAHISEDLNRWMGRAP

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=221, Percent_Identity=31.6742081447964, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI8922871, Length=187, Percent_Identity=33.1550802139037, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 30207; Mature: 30076

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMRQSLHVMQSASNSSPHAPDRWFPTRKPLTDPRLRLFCLPYAGGSVAIYNQWSQGLPA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCC
GVELCPVQLPGRERRLSEKPIGSLPALVDALLPAIAPLLDRPFAFFGYSMGARISLELAR
CCEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEHHHHHH
RLQARNGPRPVGLFLGAAGPPSVNTREPIHHLPEPEFIAQLRRYDGTPEEIFQHRELLEL
HHHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
VLPMLRADFGIAFTEDGPQPAKLEVPISVVGSPEDKHVPTANLERWRDETRSEDVRVRLF
HHHHHHHHCCEEECCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEEE
PGGHFFIKSQRDALLAHISEDLNRWMGRAP
CCCEEEEECCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AMRQSLHVMQSASNSSPHAPDRWFPTRKPLTDPRLRLFCLPYAGGSVAIYNQWSQGLPA
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCC
GVELCPVQLPGRERRLSEKPIGSLPALVDALLPAIAPLLDRPFAFFGYSMGARISLELAR
CCEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEHHHHHH
RLQARNGPRPVGLFLGAAGPPSVNTREPIHHLPEPEFIAQLRRYDGTPEEIFQHRELLEL
HHHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
VLPMLRADFGIAFTEDGPQPAKLEVPISVVGSPEDKHVPTANLERWRDETRSEDVRVRLF
HHHHHHHHCCEEECCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEEE
PGGHFFIKSQRDALLAHISEDLNRWMGRAP
CCCEEEEECCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]