Click here to switch to the map view.

The map label for this gene is gfo [H]

Identifier: 108757471

GI number: 108757471

Start: 4029582

End: 4030748

Strand: Direct

Name: gfo [H]

Synonym: MXAN_3460

Alternate gene names: 108757471

Gene position: 4029582-4030748 (Clockwise)

Preceding gene: 108758046

Following gene: 108757037

Centisome position: 44.09

GC content: 68.04

Gene sequence:

>1167_bases
GTGGCGGGTGCCTCGGGGGCCCAGCGTGTCTCTCATACGCGGAGGCAATCGATGGCACAGGGCAGCTCGCGGCGAATCCG
GTATGCGGTGGTGGGGGCGGGGAATATCGCGCAGGTGGCTGTACTTCCGGCCTTCCAGCACGCCCTTGAGAACTCGGAGT
TGGTGGCGCTCTTTTCCTCCGACGCGGAGAAGCGCGACGTGCTGGGGAAGATGTACGGCGTGCGCCACACCGCGAGCTAC
GACGACCTTGAGCAGGTGCTGCGCGACGCGGACGTGGACGCGGTGTACATCGCGCTGCCCAACACCCAGCATCGCGCCTT
CACCGAGCGGGCCGCTCGCGCGGGTGTGCACGTCCTCTGCGAGAAGCCCATGGCGACCTCGGTGGAGGACTGTGAGGCGA
TGATTCGCGTCACGGACGAGAATCACGTCAAGCTGATGATCGCCTACCGGCTCCACTTCGAGGAGGCGAACCTGCGGGCC
ATTGACCTGCTGCGTTCGGGGCGCCTGGGTGAGCCGCTGATGATGTCGGCGCTGCTGACGCAGCAGGTGCGGACCGGGGA
CATCCGGACGCGCGTGGACGTGGGCGGAGGCGCGCTGCTCGACGAAGGGCCGTACCCCATCAACGCGGCGCGCTACCTCT
TCCGTGACGAGCCCACCGAGGTGTTCTGCTACACCAACGAGGAGCAGGACCCTCGCTTCAAGGGCGTGGACGCCACGGCC
TTCGCGTTGATGCGCTTCTCGAATGGGCGCATCGCGCAGTTCGGCATCAGCCACGCCGCATCGGCGGTCTCCAGCTACCG
GGTGGTGGGGGAGAAGGGCGACCTGCTCGTCGAGTCCGCGTTTGGCTACGAGAAGGAGCGCAAGCATGTCCTCACGCTGG
AGGGCAAGACGGAGGAGCGCGTCTTCGCGACGCACGACCAGTTCGCGCCGGAGCTGCTCTACTTCTCGAAGTGCGTGCTG
GAGGACCAGGAGCCCGGGCCGTCCGGCCGGGAAGGGCTCGCGGACGTGCGCGTCATCACCGCGATGCAGGAGTCCGCGAG
GACGGGGCGCCCGGTGAAGCTGGAAGCATTCCCGATGAAGCGGCGGCCGTCCCTGGACCAGCTCATCGTCCGCCCCGCGG
CCAGGCCGCCAGCGCCAGTGAACGCGCCCGCGCCAGTGCAAGGATGA

Upstream 100 bases:

>100_bases
CGGAGTGGCATCAGCGCCACGACGCGGAAGTGGGCTGAGGCGGCTCGGGGGGCCGCCTGCTGTCCGGACGGGCGGCACGA
CGTTGCCCGGAGCGCGGGTT

Downstream 100 bases:

>100_bases
ACTTGCGTCCACTGGAAATATTTCCCGCGCGCGAGCTTCTTCGTGCGCTGAATGTGCGGCGACATCCGCCTCCGCAAGTC
GTGTCAGACCCTTGATGCAT

Product: Gfo/Idh/MocA family oxidoreductase

Products: NA

Alternate protein names: GFOR [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAGASGAQRVSHTRRQSMAQGSSRRIRYAVVGAGNIAQVAVLPAFQHALENSELVALFSSDAEKRDVLGKMYGVRHTASY
DDLEQVLRDADVDAVYIALPNTQHRAFTERAARAGVHVLCEKPMATSVEDCEAMIRVTDENHVKLMIAYRLHFEEANLRA
IDLLRSGRLGEPLMMSALLTQQVRTGDIRTRVDVGGGALLDEGPYPINAARYLFRDEPTEVFCYTNEEQDPRFKGVDATA
FALMRFSNGRIAQFGISHAASAVSSYRVVGEKGDLLVESAFGYEKERKHVLTLEGKTEERVFATHDQFAPELLYFSKCVL
EDQEPGPSGREGLADVRVITAMQESARTGRPVKLEAFPMKRRPSLDQLIVRPAARPPAPVNAPAPVQG

Sequences:

>Translated_388_residues
MAGASGAQRVSHTRRQSMAQGSSRRIRYAVVGAGNIAQVAVLPAFQHALENSELVALFSSDAEKRDVLGKMYGVRHTASY
DDLEQVLRDADVDAVYIALPNTQHRAFTERAARAGVHVLCEKPMATSVEDCEAMIRVTDENHVKLMIAYRLHFEEANLRA
IDLLRSGRLGEPLMMSALLTQQVRTGDIRTRVDVGGGALLDEGPYPINAARYLFRDEPTEVFCYTNEEQDPRFKGVDATA
FALMRFSNGRIAQFGISHAASAVSSYRVVGEKGDLLVESAFGYEKERKHVLTLEGKTEERVFATHDQFAPELLYFSKCVL
EDQEPGPSGREGLADVRVITAMQESARTGRPVKLEAFPMKRRPSLDQLIVRPAARPPAPVNAPAPVQG
>Mature_387_residues
AGASGAQRVSHTRRQSMAQGSSRRIRYAVVGAGNIAQVAVLPAFQHALENSELVALFSSDAEKRDVLGKMYGVRHTASYD
DLEQVLRDADVDAVYIALPNTQHRAFTERAARAGVHVLCEKPMATSVEDCEAMIRVTDENHVKLMIAYRLHFEEANLRAI
DLLRSGRLGEPLMMSALLTQQVRTGDIRTRVDVGGGALLDEGPYPINAARYLFRDEPTEVFCYTNEEQDPRFKGVDATAF
ALMRFSNGRIAQFGISHAASAVSSYRVVGEKGDLLVESAFGYEKERKHVLTLEGKTEERVFATHDQFAPELLYFSKCVLE
DQEPGPSGREGLADVRVITAMQESARTGRPVKLEAFPMKRRPSLDQLIVRPAARPPAPVNAPAPVQG

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=366, Percent_Identity=24.8633879781421, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082405, Length=260, Percent_Identity=25.3846153846154, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693182, Length=263, Percent_Identity=27.3764258555133, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24581117, Length=259, Percent_Identity=25.0965250965251, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008354
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.99.28 [H]

Molecular weight: Translated: 42768; Mature: 42637

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGASGAQRVSHTRRQSMAQGSSRRIRYAVVGAGNIAQVAVLPAFQHALENSELVALFSS
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECC
DAEKRDVLGKMYGVRHTASYDDLEQVLRDADVDAVYIALPNTQHRAFTERAARAGVHVLC
CCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCEEEEE
EKPMATSVEDCEAMIRVTDENHVKLMIAYRLHFEEANLRAIDLLRSGRLGEPLMMSALLT
CCCCCCCHHHHHEEEEECCCCCEEEEEEEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHH
QQVRTGDIRTRVDVGGGALLDEGPYPINAARYLFRDEPTEVFCYTNEEQDPRFKGVDATA
HHHHCCCCEEEEECCCCEEECCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHH
FALMRFSNGRIAQFGISHAASAVSSYRVVGEKGDLLVESAFGYEKERKHVLTLEGKTEER
HEEEEECCCCEEEHHHHHHHHHHHHHEEECCCCCEEEEHHCCCCCCCCEEEEECCCCCCC
VFATHDQFAPELLYFSKCVLEDQEPGPSGREGLADVRVITAMQESARTGRPVKLEAFPMK
EEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
RRPSLDQLIVRPAARPPAPVNAPAPVQG
CCCCHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGASGAQRVSHTRRQSMAQGSSRRIRYAVVGAGNIAQVAVLPAFQHALENSELVALFSS
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECC
DAEKRDVLGKMYGVRHTASYDDLEQVLRDADVDAVYIALPNTQHRAFTERAARAGVHVLC
CCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCEEEEE
EKPMATSVEDCEAMIRVTDENHVKLMIAYRLHFEEANLRAIDLLRSGRLGEPLMMSALLT
CCCCCCCHHHHHEEEEECCCCCEEEEEEEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHH
QQVRTGDIRTRVDVGGGALLDEGPYPINAARYLFRDEPTEVFCYTNEEQDPRFKGVDATA
HHHHCCCCEEEEECCCCEEECCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHH
FALMRFSNGRIAQFGISHAASAVSSYRVVGEKGDLLVESAFGYEKERKHVLTLEGKTEER
HEEEEECCCCEEEHHHHHHHHHHHHHEEECCCCCEEEEHHCCCCCCCCEEEEECCCCCCC
VFATHDQFAPELLYFSKCVLEDQEPGPSGREGLADVRVITAMQESARTGRPVKLEAFPMK
EEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
RRPSLDQLIVRPAARPPAPVNAPAPVQG
CCCCHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537789; 8472911; 8994968 [H]