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The map label for this gene is sdhB [H]

Identifier: 108757195

GI number: 108757195

Start: 4125670

End: 4126479

Strand: Direct

Name: sdhB [H]

Synonym: MXAN_3540

Alternate gene names: 108757195

Gene position: 4125670-4126479 (Clockwise)

Preceding gene: 108761290

Following gene: 108761542

Centisome position: 45.14

GC content: 65.43

Gene sequence:

>810_bases
ATGGACACTGCACAAGCATCCGCTGTCACCACCAAGACCATCACCTTCCGCATCTGGCGGCAGGATGATCCCGCGAAGCC
AGGCCACTTCGATGAGTTCAAGGTTCCCTATGCGAAGGGCGCCAACGTCATCTCGTGCCTGATGGAGATCCAGCGCAACC
CCGTCACCGTGGAGGGCAAGCGCGTGGCCCCGGTGATCTGGGACGCCGCATGTCTGGAAGAGGTCTGTGGCAGCTGCGCC
ATGAACATCAACGGCCGCGTGCGCATGGCCTGCTCGGCGCTGATCGACAAGCTGGAGCAGCCGATCACGCTGGAGCCCAT
GAGCAAGTTCCCCGTGGTGCGTGACCTCACGGTGAACCGCGACCGCATGTTCGACGCGCTCAAGCGCATCAAGGGCTGGG
TGCCCATCGACGGCACGCACAACCTGGGGCCGGGGCCGCGCCAGGCGCCCGTGGACCAGTCGGTGATGTACGTGCTGTCC
ACGTGCATCACCTGCGGCAGCTGCCTGGAGGCGTGCCCCCAGGTGACGCAGGAGAACGACTTCGTGGGCGCGGCGGCCAT
CAGCCAGGCCCGCCTGTTCAACATGAACCCCACGGGCAAGATGAACTCCGAGGAGCGCGTGCGCTCGCTCATGGGGCCCG
GCGGCATCCAGGACTGCGGCAAGGCGCAGAACTGCGTGAAGGTCTGCCCGAAGGAGATTCCGCTCGTCACGTCCATCGCG
GTGATGAACCGCGAGGTGACCAAGCTCACCATCAAGGACATCTTCTTCCAGGACGAGGCCCCCAAGGGCCACGGCAGCGG
TCCGGGGTAG

Upstream 100 bases:

>100_bases
ACTACGAGGACATCCCTACGCCCGTGCTGGACCCCGAGCCGCGCTGGTACGCCTGAGACGGGAACCACTCAACCGATTTG
GAAGTGAAGGGTCGAGCCAC

Downstream 100 bases:

>100_bases
GGCGCTCGCCAGCGACTTCCCGGCGTTCTCTGGCTTCAAGCGGCCCCGGGCCGGCGTCCATTCGAGACGCCGGGCGGGGC
CGCCGCTGTTTGGGTGTCCG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MDTAQASAVTTKTITFRIWRQDDPAKPGHFDEFKVPYAKGANVISCLMEIQRNPVTVEGKRVAPVIWDAACLEEVCGSCA
MNINGRVRMACSALIDKLEQPITLEPMSKFPVVRDLTVNRDRMFDALKRIKGWVPIDGTHNLGPGPRQAPVDQSVMYVLS
TCITCGSCLEACPQVTQENDFVGAAAISQARLFNMNPTGKMNSEERVRSLMGPGGIQDCGKAQNCVKVCPKEIPLVTSIA
VMNREVTKLTIKDIFFQDEAPKGHGSGPG

Sequences:

>Translated_269_residues
MDTAQASAVTTKTITFRIWRQDDPAKPGHFDEFKVPYAKGANVISCLMEIQRNPVTVEGKRVAPVIWDAACLEEVCGSCA
MNINGRVRMACSALIDKLEQPITLEPMSKFPVVRDLTVNRDRMFDALKRIKGWVPIDGTHNLGPGPRQAPVDQSVMYVLS
TCITCGSCLEACPQVTQENDFVGAAAISQARLFNMNPTGKMNSEERVRSLMGPGGIQDCGKAQNCVKVCPKEIPLVTSIA
VMNREVTKLTIKDIFFQDEAPKGHGSGPG
>Mature_269_residues
MDTAQASAVTTKTITFRIWRQDDPAKPGHFDEFKVPYAKGANVISCLMEIQRNPVTVEGKRVAPVIWDAACLEEVCGSCA
MNINGRVRMACSALIDKLEQPITLEPMSKFPVVRDLTVNRDRMFDALKRIKGWVPIDGTHNLGPGPRQAPVDQSVMYVLS
TCITCGSCLEACPQVTQENDFVGAAAISQARLFNMNPTGKMNSEERVRSLMGPGGIQDCGKAQNCVKVCPKEIPLVTSIA
VMNREVTKLTIKDIFFQDEAPKGHGSGPG

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=246, Percent_Identity=26.8292682926829, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1790596, Length=222, Percent_Identity=27.9279279279279, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786943, Length=168, Percent_Identity=30.3571428571429, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17533915, Length=246, Percent_Identity=26.0162601626016, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322987, Length=243, Percent_Identity=25.5144032921811, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24643156, Length=244, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17137106, Length=255, Percent_Identity=25.0980392156863, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29341; Mature: 29341

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTAQASAVTTKTITFRIWRQDDPAKPGHFDEFKVPYAKGANVISCLMEIQRNPVTVEGK
CCCCHHHHEEEEEEEEEEEECCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHCCCEEECCC
RVAPVIWDAACLEEVCGSCAMNINGRVRMACSALIDKLEQPITLEPMSKFPVVRDLTVNR
EECHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCEECCHHHCCEEEECCCCH
DRMFDALKRIKGWVPIDGTHNLGPGPRQAPVDQSVMYVLSTCITCGSCLEACPQVTQEND
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FVGAAAISQARLFNMNPTGKMNSEERVRSLMGPGGIQDCGKAQNCVKVCPKEIPLVTSIA
CCHHHHHHHHHEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VMNREVTKLTIKDIFFQDEAPKGHGSGPG
HHCCHHHHEEHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDTAQASAVTTKTITFRIWRQDDPAKPGHFDEFKVPYAKGANVISCLMEIQRNPVTVEGK
CCCCHHHHEEEEEEEEEEEECCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHCCCEEECCC
RVAPVIWDAACLEEVCGSCAMNINGRVRMACSALIDKLEQPITLEPMSKFPVVRDLTVNR
EECHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCEECCHHHCCEEEECCCCH
DRMFDALKRIKGWVPIDGTHNLGPGPRQAPVDQSVMYVLSTCITCGSCLEACPQVTQEND
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FVGAAAISQARLFNMNPTGKMNSEERVRSLMGPGGIQDCGKAQNCVKVCPKEIPLVTSIA
CCHHHHHHHHHEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VMNREVTKLTIKDIFFQDEAPKGHGSGPG
HHCCHHHHEEHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]