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The map label for this gene is rtcA [H]

Identifier: 108756990

GI number: 108756990

Start: 4575834

End: 4576916

Strand: Reverse

Name: rtcA [H]

Synonym: MXAN_3809

Alternate gene names: 108756990

Gene position: 4576916-4575834 (Counterclockwise)

Preceding gene: 108757751

Following gene: 108757755

Centisome position: 50.08

GC content: 73.22

Gene sequence:

>1083_bases
ATGACCGGCACCCAGGGGCCCGACACCGGGCTGGTGCGGCTGGATGGGAGTGAGGGCGAAGGGGGCGGCCAGATTCTCCG
CTCCGCGCTGTCGCTGTCGCTCATCACCGGCCGCCCGTTCCACATCACGCGCCTGCGCGAGCGACGTGATCCGCCCGGTC
TGCGTCCCCAGCACCTGGCCTGCGTACGCGGCGCCGAGGCCCTGTGTGGCGGTGCCGCTTTTTCCGAGGGCGCCACCGTC
GGCGCCTCCGAGCTCTCCTTCACCCCGGCCCCCGTGCGCGCCGGCGACTACCTGCTGGAGGTGGGCACCGCGGGCAGCAC
GCCGTTGCTCTTCCAGTGCCTCGTCTATCCGCTGGCCCTGGCCGGCGGAGGACGGCTGACCTTGCGAGGCGGCACGCACC
TGCCCCATAGCCCCAGCTTCCACTATGTGGCCACCGTCTGGCAGCCGGTGGCGCATGCGTATGGCCTGCCGGTGCTGCTG
TCCCTGGTGCACGCCGGCTTCTACCCGGAGGGCGCGGGGGAGATTGTCGCGGAGGTGGGGCCACCGCAGGAGCCGCCCCG
GCTGGTGGAGCTGCCCGCGCGAGGCATGTTGCGCGAGGTCCGCGTGTCGTCCTTCACCGGCGGGCTGCCGTTCACCATCG
CCGAGCGTCAATCCAGGGCCGCCGTGGGGGCGCTGCGTGAGCGCGGCATCCTGGCGGAGGCGGACAACCGCCCGCTGGCG
GTGACGCGCTCGGTGGGGACCGTCACTTTCGTCCTGGCCCAGTTCGAGCACACCATCGCGGGCTTCACCGCGCTGGGAGA
GCGGGGCCGCCCCGCCGAGGACGTGGGTCGCGAGGGCGGAGAAGCCCTGGCGCGGTTCATGGAGACGGGTGGGGCGCTCG
ACGAGCACCTTGCCGATCAGATTCTCCTGCCCGCCGCACTGCTGGCCGCCGGACGCCTGGGGCCGGCGTCACCGGGCACC
ACGCGCTTCACGGCGGCGCGAATCACCGACCACCTCACCACCCACGCCCGTGTCGTGGAGCGCTTCCTGCCCGTGCGCGT
CACGGTGGATGCGGGAGGCTCCGTGGAGGTCCGGCCCGCCTGA

Upstream 100 bases:

>100_bases
TGCAGCGGCGAAGGGAAGGGTGTTCTCGTGGGGGTGCCAGCCTTGCGTTCCTGTTACCCTGGGCCTTCATTCACGCGGTG
GCACCTGAAACGGGAGGGAC

Downstream 100 bases:

>100_bases
AGTCCGGGCCGGAACCCGCTCAGGCCACTTCGTCGTCGCCGCGGTTGGCTCCGAAGGTGTTCTGCCCGGCGATGTCCTTG
GACGTGTTCCGGTAGGCGCG

Product: RNA 3'-terminal phosphate cyclase

Products: NA

Alternate protein names: RNA cyclase; RNA-3'-phosphate cyclase [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTGTQGPDTGLVRLDGSEGEGGGQILRSALSLSLITGRPFHITRLRERRDPPGLRPQHLACVRGAEALCGGAAFSEGATV
GASELSFTPAPVRAGDYLLEVGTAGSTPLLFQCLVYPLALAGGGRLTLRGGTHLPHSPSFHYVATVWQPVAHAYGLPVLL
SLVHAGFYPEGAGEIVAEVGPPQEPPRLVELPARGMLREVRVSSFTGGLPFTIAERQSRAAVGALRERGILAEADNRPLA
VTRSVGTVTFVLAQFEHTIAGFTALGERGRPAEDVGREGGEALARFMETGGALDEHLADQILLPAALLAAGRLGPASPGT
TRFTAARITDHLTTHARVVERFLPVRVTVDAGGSVEVRPA

Sequences:

>Translated_360_residues
MTGTQGPDTGLVRLDGSEGEGGGQILRSALSLSLITGRPFHITRLRERRDPPGLRPQHLACVRGAEALCGGAAFSEGATV
GASELSFTPAPVRAGDYLLEVGTAGSTPLLFQCLVYPLALAGGGRLTLRGGTHLPHSPSFHYVATVWQPVAHAYGLPVLL
SLVHAGFYPEGAGEIVAEVGPPQEPPRLVELPARGMLREVRVSSFTGGLPFTIAERQSRAAVGALRERGILAEADNRPLA
VTRSVGTVTFVLAQFEHTIAGFTALGERGRPAEDVGREGGEALARFMETGGALDEHLADQILLPAALLAAGRLGPASPGT
TRFTAARITDHLTTHARVVERFLPVRVTVDAGGSVEVRPA
>Mature_359_residues
TGTQGPDTGLVRLDGSEGEGGGQILRSALSLSLITGRPFHITRLRERRDPPGLRPQHLACVRGAEALCGGAAFSEGATVG
ASELSFTPAPVRAGDYLLEVGTAGSTPLLFQCLVYPLALAGGGRLTLRGGTHLPHSPSFHYVATVWQPVAHAYGLPVLLS
LVHAGFYPEGAGEIVAEVGPPQEPPRLVELPARGMLREVRVSSFTGGLPFTIAERQSRAAVGALRERGILAEADNRPLAV
TRSVGTVTFVLAQFEHTIAGFTALGERGRPAEDVGREGGEALARFMETGGALDEHLADQILLPAALLAAGRLGPASPGTT
RFTAARITDHLTTHARVVERFLPVRVTVDAGGSVEVRPA

Specific function: Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps:(A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A;

COG id: COG0430

COG function: function code A; RNA 3'-terminal phosphate cyclase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4506589, Length=350, Percent_Identity=31.4285714285714, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI195927044, Length=363, Percent_Identity=30.3030303030303, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI48994937, Length=340, Percent_Identity=37.6470588235294, Blast_Score=194, Evalue=1e-50,
Organism=Drosophila melanogaster, GI18543269, Length=357, Percent_Identity=27.7310924369748, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000228
- InterPro:   IPR013796
- InterPro:   IPR020723
- InterPro:   IPR017770
- InterPro:   IPR013792 [H]

Pfam domain/function: PF01137 RTC; PF05189 RTC_insert [H]

EC number: =6.5.1.4 [H]

Molecular weight: Translated: 37677; Mature: 37546

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTQGPDTGLVRLDGSEGEGGGQILRSALSLSLITGRPFHITRLRERRDPPGLRPQHLA
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEECCCCEEEHHHHHHCCCCCCCHHHHH
CVRGAEALCGGAAFSEGATVGASELSFTPAPVRAGDYLLEVGTAGSTPLLFQCLVYPLAL
HHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
AGGGRLTLRGGTHLPHSPSFHYVATVWQPVAHAYGLPVLLSLVHAGFYPEGAGEIVAEVG
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCC
PPQEPPRLVELPARGMLREVRVSSFTGGLPFTIAERQSRAAVGALRERGILAEADNRPLA
CCCCCCCEEECCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCEEECCCCCEE
VTRSVGTVTFVLAQFEHTIAGFTALGERGRPAEDVGREGGEALARFMETGGALDEHLADQ
EEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
ILLPAALLAAGRLGPASPGTTRFTAARITDHLTTHARVVERFLPVRVTVDAGGSVEVRPA
HHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCC
>Mature Secondary Structure 
TGTQGPDTGLVRLDGSEGEGGGQILRSALSLSLITGRPFHITRLRERRDPPGLRPQHLA
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEECCCCEEEHHHHHHCCCCCCCHHHHH
CVRGAEALCGGAAFSEGATVGASELSFTPAPVRAGDYLLEVGTAGSTPLLFQCLVYPLAL
HHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
AGGGRLTLRGGTHLPHSPSFHYVATVWQPVAHAYGLPVLLSLVHAGFYPEGAGEIVAEVG
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCC
PPQEPPRLVELPARGMLREVRVSSFTGGLPFTIAERQSRAAVGALRERGILAEADNRPLA
CCCCCCCEEECCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCEEECCCCCEE
VTRSVGTVTFVLAQFEHTIAGFTALGERGRPAEDVGREGGEALARFMETGGALDEHLADQ
EEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
ILLPAALLAAGRLGPASPGTTRFTAARITDHLTTHARVVERFLPVRVTVDAGGSVEVRPA
HHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA