Click here to switch to the map view.

The map label for this gene is gapB [H]

Identifier: 108563718

GI number: 108563718

Start: 1338254

End: 1339246

Strand: Reverse

Name: gapB [H]

Synonym: HPAG1_1293

Alternate gene names: 108563718

Gene position: 1339246-1338254 (Counterclockwise)

Preceding gene: 108563719

Following gene: 108563717

Centisome position: 83.89

GC content: 43.71

Gene sequence:

>993_bases
ATGCCAATTAGAATCGCTATCAATGGGACTGGGCGCATCGGTTTGTGCGCTATAAGAGTCGCTAGTCAAAGAAAGGATAT
AGAAATTGTCGCTATCAATTCTACCGCTGAATTAGAAACTCTTTTGCACTTGATCCGCCATGACAGCGTGCATGGGCATT
TTGAAGCCCAATTAAACGCCAATAGAACCCTAAATATCGGGTATAGTAAAAACATTTTAGTGTTGAGCGAGCGAGACATC
AACAAGCTTGATTTCTCTGCCGCTAACGCAGAAATCATCATAGAATGCACCGGGAAATTCAATTCCTTAGAAGCTTCAAG
CGCTCATCTTAAAAACAGCGTGAAAAAAGTCATCATCTCCGCTCCCGCGCAAAACGCCCCCACCTTTGTCTATGGGGTGA
ATCACACCCATTACCATAATGAAAGCGTGATTTCTAACGCCTCTTGCACGACTAACGCTAGCGCTCCTTTATTAAAAATC
TTAGATGAAGCCTTTAAAGTAGAAAACGCGCTTTTAACCACCATCCACAGCTACACTAACGATCAAAACCTCTTAGACAC
CAAGCACAAAGACATCCGCCGCGCTAGAGCGGCTGGTTTAAACCTCATCCCCACAAGCACCGGCGTGAGCAAAGCCATTT
CGCTAGTCTTACCGCATTTAGGCCATAAGATCACAGGACTTGCGATTAGAGTGCCTACCCCTAACGTGAGCTTAGTGGAT
CTATCTTTAAGCTTTAAGAAATCCGTGAGTAAAGCGAGCGTTCAGCATGCGCTTAAAGACGCTTGTAAGCATGCCTTTAA
AGGGGTTGTGGGTATTGATGAAGAAAGGCTTGTTTCAAGCGATTTTATTTCTTCGCCTTTTAGCGCGATCGTGATTGATG
ATCAAATCATGACAATAGGCGAAAAAAATGCTAAAGTATTGGCATGGTATGATAATGAGATGGGTTATAGCGAGCGCTTG
ATAGACATGGCGCAGTATATAGCGCAAAATTAA

Upstream 100 bases:

>100_bases
TTCAGTTTATGATTAATGATTAATGAGGCAGAACCCCTTAAGAATGCCTTGATTTAAGAGCATTTGTGATAAAATGGTGG
CTTTTAAATAAAGGGAAAAC

Downstream 100 bases:

>100_bases
AAGAAAGGATTTTTCATGTTAGCTAAAATGTCGTTTATGCAAAATGTTAAAAACATTCAAGAAGTGGAAGTGAGCCATAA
AAGGGTGCTTATTAGAGTGG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNANRTLNIGYSKNILVLSERDI
NKLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNAPTFVYGVNHTHYHNESVISNASCTTNASAPLLKI
LDEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGHKITGLAIRVPTPNVSLVD
LSLSFKKSVSKASVQHALKDACKHAFKGVVGIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERL
IDMAQYIAQN

Sequences:

>Translated_330_residues
MPIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNANRTLNIGYSKNILVLSERDI
NKLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNAPTFVYGVNHTHYHNESVISNASCTTNASAPLLKI
LDEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGHKITGLAIRVPTPNVSLVD
LSLSFKKSVSKASVQHALKDACKHAFKGVVGIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERL
IDMAQYIAQN
>Mature_329_residues
PIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNANRTLNIGYSKNILVLSERDIN
KLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNAPTFVYGVNHTHYHNESVISNASCTTNASAPLLKIL
DEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGHKITGLAIRVPTPNVSLVDL
SLSFKKSVSKASVQHALKDACKHAFKGVVGIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERLI
DMAQYIAQN

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=38.9057750759878, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=35.8662613981763, Blast_Score=234, Evalue=6e-62,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=38.368580060423, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1789295, Length=328, Percent_Identity=38.719512195122, Blast_Score=238, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=39.039039039039, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=38.7387387387387, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=39.3393393393393, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=39.3393393393393, Blast_Score=254, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=41.2121212121212, Blast_Score=271, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=40, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=39.6969696969697, Blast_Score=261, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=40.3669724770642, Blast_Score=260, Evalue=9e-70,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=40.3669724770642, Blast_Score=260, Evalue=9e-70,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=39.7553516819572, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=39.7553516819572, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=40, Blast_Score=257, Evalue=7e-69,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 36010; Mature: 35878

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNA
CCEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECC
NRTLNIGYSKNILVLSERDINKLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIIS
CEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEEE
APAQNAPTFVYGVNHTHYHNESVISNASCTTNASAPLLKILDEAFKVENALLTTIHSYTN
CCCCCCCEEEEECCCCEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGHKITGLAIRVPTPNVSLVD
CCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEE
LSLSFKKSVSKASVQHALKDACKHAFKGVVGIDEERLVSSDFISSPFSAIVIDDQIMTIG
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCEEEEEC
EKNAKVLAWYDNEMGYSERLIDMAQYIAQN
CCCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNA
CEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECC
NRTLNIGYSKNILVLSERDINKLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIIS
CEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEEE
APAQNAPTFVYGVNHTHYHNESVISNASCTTNASAPLLKILDEAFKVENALLTTIHSYTN
CCCCCCCEEEEECCCCEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGHKITGLAIRVPTPNVSLVD
CCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEE
LSLSFKKSVSKASVQHALKDACKHAFKGVVGIDEERLVSSDFISSPFSAIVIDDQIMTIG
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCEEEEEC
EKNAKVLAWYDNEMGYSERLIDMAQYIAQN
CCCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]