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The map label for this gene is sotB [H]

Identifier: 108563550

GI number: 108563550

Start: 1185171

End: 1186346

Strand: Reverse

Name: sotB [H]

Synonym: HPAG1_1125

Alternate gene names: 108563550

Gene position: 1186346-1185171 (Counterclockwise)

Preceding gene: 108563552

Following gene: 108563549

Centisome position: 74.32

GC content: 43.62

Gene sequence:

>1176_bases
ATGATGATAACCAAACAATCGTATCAAAAGTTCGCCTTAATGCGGGTTTTTGTGTTTTCGCTTTCGGCGTTTATTTTTAA
CACCACGGAGTTTGTCCCTGTCGCGCTCTTATCAGATATTGCGAAAAGTTTTGAAATGGAGAGCGCAACAGTAGGGCTTA
TGATCACTGCTTATGCATGGGTGGTGTCTCTTGGCTCATTGCCTTTGATGCTGCTTAGCGCTAAAATTGAAAGGAAACGC
TTATTGCTTTTCCTTTTCGCCCTTTTTATTCTCAGCCATATCCTTTCAGCGTTAGCGTGGAATTTTTGGGTGCTACTCCT
TTCTCGTATGGGTATCGCTTTTACCCACTCTATTTTTTGGTCCATCACGGCTTCTTTAGTCATTCGTGTCGCGCCAAGAA
ATAAAAAACAACAAGCTTTAGGGTTATTGGCGTTAGGGAGTTCGTTGGCGATGATTTTAGGGTTGCCGCTTGGGAGGATC
ATCGGGCAAATGTTAGATTGGCGATCCACTTTTGGCGTGATCGGGGGCGTTGCGACTCTTATAGCGTTGCTTATGTGGAA
ATTGCTCCCGCATTTACCGAGTAGAAACGCAGGCACGCTCGCAAGTGTCCCTATACTAATGAAACGGCCGCTTTTAATGG
GGATTTATTTGCTTGTGATCATGGTCATCTCTGGACATTTCACCACTTATAGCTATATTGAGCCTTTTATCATTCAAATC
AGCCAATTTTCTCCTGACATTACGACGCTAATGTTGTTTGTGTTTGGGTTAGCGGGCGTGGCGGGGAGTTTTTTGTTCAG
CCGTTTGTATGCGAAAAATTCAAGAAAATTCATCGCTTTTGCAATGGTTTTAGTCATTTGCCCGCAACTCTTGCTTTTTG
TGTTTAAAAACTTAGAGTGGGTGATCTTCTTGCAAATTTTCTTATGGGGAATAGGGATCACTTCACTCACCATTGCGTTG
CAAATGAGGGTGTTACAGCTTGCCCCAGATGCCACGGATGTCGCGAGCGCGATTTTTTCGGGGAGCTATAATGTGGGGAT
TGGATCAGGAGCGCTGTTTGGCAGTATTGTGATCCACCAATTAGGGCTAGAATATATTGGCTTTGTGGGCGGAGCTTTAG
GTTTGTTGGCGCTGTTTTGGCTTAGATTCATTACGATAAAGTTTAAAAAAACATAA

Upstream 100 bases:

>100_bases
AATATTTGTTTTAACCACCCCCCAATTTACAAGCGATTAAAATTTTTGTCTTATAATCCAAGTTTTCAAATGGAATAAAA
TTTAACCCCTTAAGATTTAA

Downstream 100 bases:

>100_bases
GGAGCGTTAAAAGGATTAGCCTAATATAAGGAAATCCCTTTTGCGTTAAAAACCATTTTTTAATGATACCGCTTAATAAC
CGCACTAACGGATAGATTGT

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKR
LLLFLFALFILSHILSALAWNFWVLLLSRMGIAFTHSIFWSITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRI
IGQMLDWRSTFGVIGGVATLIALLMWKLLPHLPSRNAGTLASVPILMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
SQFSPDITTLMLFVFGLAGVAGSFLFSRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVIFLQIFLWGIGITSLTIAL
QMRVLQLAPDATDVASAIFSGSYNVGIGSGALFGSIVIHQLGLEYIGFVGGALGLLALFWLRFITIKFKKT

Sequences:

>Translated_391_residues
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKR
LLLFLFALFILSHILSALAWNFWVLLLSRMGIAFTHSIFWSITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRI
IGQMLDWRSTFGVIGGVATLIALLMWKLLPHLPSRNAGTLASVPILMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
SQFSPDITTLMLFVFGLAGVAGSFLFSRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVIFLQIFLWGIGITSLTIAL
QMRVLQLAPDATDVASAIFSGSYNVGIGSGALFGSIVIHQLGLEYIGFVGGALGLLALFWLRFITIKFKKT
>Mature_391_residues
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKR
LLLFLFALFILSHILSALAWNFWVLLLSRMGIAFTHSIFWSITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRI
IGQMLDWRSTFGVIGGVATLIALLMWKLLPHLPSRNAGTLASVPILMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
SQFSPDITTLMLFVFGLAGVAGSFLFSRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVIFLQIFLWGIGITSLTIAL
QMRVLQLAPDATDVASAIFSGSYNVGIGSGALFGSIVIHQLGLEYIGFVGGALGLLALFWLRFITIKFKKT

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=379, Percent_Identity=50.131926121372, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI1787947, Length=328, Percent_Identity=28.3536585365854, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI145693198, Length=362, Percent_Identity=25.1381215469613, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786595, Length=349, Percent_Identity=25.7879656160458, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43273; Mature: 43273

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAW
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VVSLGSLPLMLLSAKIERKRLLLFLFALFILSHILSALAWNFWVLLLSRMGIAFTHSIFW
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRIIGQMLDWRSTFGVIGGVATL
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IALLMWKLLPHLPSRNAGTLASVPILMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
HHHHHHHHHHCCCCCCCCCHHHCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SQFSPDITTLMLFVFGLAGVAGSFLFSRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
VIFLQIFLWGIGITSLTIALQMRVLQLAPDATDVASAIFSGSYNVGIGSGALFGSIVIHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LGLEYIGFVGGALGLLALFWLRFITIKFKKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAW
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VVSLGSLPLMLLSAKIERKRLLLFLFALFILSHILSALAWNFWVLLLSRMGIAFTHSIFW
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRIIGQMLDWRSTFGVIGGVATL
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IALLMWKLLPHLPSRNAGTLASVPILMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
HHHHHHHHHHCCCCCCCCCHHHCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SQFSPDITTLMLFVFGLAGVAGSFLFSRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
VIFLQIFLWGIGITSLTIALQMRVLQLAPDATDVASAIFSGSYNVGIGSGALFGSIVIHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LGLEYIGFVGGALGLLALFWLRFITIKFKKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA