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The map label for this gene is 108563549

Identifier: 108563549

GI number: 108563549

Start: 1183631

End: 1185010

Strand: Reverse

Name: 108563549

Synonym: HPAG1_1123

Alternate gene names: NA

Gene position: 1185010-1183631 (Counterclockwise)

Preceding gene: 108563550

Following gene: 108563547

Centisome position: 74.23

GC content: 39.57

Gene sequence:

>1380_bases
ATGCTCAAAAAAAAGATTGATTTGCATAAAGATTCTATTAGGAAGCTCTTTTTTTATTATTTTATCCCTTTAGCTTTTTC
TATGATTTCACTTTCCACTTATTCTATGATAGATGGCATGTTTGTGGGCAAGAAACTGGGTAAAGAAGCTATCGCTGCGG
TCAATATCGCATGGCCTATTTTTCCAGGGCTCATTGCGTATGAATTGCTTTTTGGTTTTGGGGCAGCGAGTATTGTGGGG
TATTTTTTGGGTCAAAATAAAACCCATAGGGCTAGGCTTGTGTTTAGCAGCGTGTTTTATTTTGTCGCTATAAGCGCCTT
TATTTTGAGCATGGCGTTATTGCCGTTTAGCGAAACTATCGCGCGTTTTTTTGGGAGCAATGACGCTTTATTAGGCATGT
CCAAACGCTACATTGAAATCATTTTAATGGGCGCGGTTTTTATGGTCCTCCACCCTTTAGCGGATGTTTTTGTGGTGAAT
GACAAACGGCCCGTTTTAGCGATGGTAGCGATGCTGATTGGCTCGTTAGCGAATATCTTTTTCAACTACTTGTTTATTTT
TGTTTTAAAAGTGGGGGTTCAAGGCAGCGCGATAGCCACCGTGATAGGGCATGCGATAGGGGTTTTAGTCTTAATGCAGC
ATTTTTGGTTTAAAAAAGGGCAATTGTATTTTATCAAACGATTTTCCCTGTCTTCAGTCATTTCTTCAGCTAAAAGCGGC
GTGCCTCAAAGCACGGCGGAATTTAGCGCTTCTGTTATGATTTTGTTGTTTAATACCGCTATCATGCACACGGCTGGGGA
AAGGTTTGTGAGCGTGTATGGGATCGTTATGTATAATGCGATTATCTTTTTTACGACTTTGTTTGCGATTTCTCAAGGCA
TCCAACCGATTGCGAGCTTTAGCTATGGGGCTAGAAATTTAGAGCGCGTGAAAGAGGTGTTTGTCTTTGGTTTGAAAGCA
GCGTTTTGTATAGGGGTTGTTTTCTATGGCGTTTATTACTTTTTAGATGAATTTTTAATCAAGCTTTATTTACAGCCAAG
CGAACAAGACCCCCTTTTTATGCAAGAAACTAAAAGAGCGATGAATATTTATTATGTTGGCTATGTTTTTTTAGGCATGA
CTTTGTTGTGCGCGGTGTTTTTCCAATCCATCCAACGCGCTAAAAGTTCGTTTATCATCACCCTTTCGCACACGCTAGGG
TTTATCGTTATTCTATTGCCGATTTTGAGTCATTTCTATGGGATTAATGGCGTTTGGGTAACTTACCCTATCGCGCAATT
TTTAGCGTTTTTAGTAGCGTTAGGGGTAACTTATTACGAAATCAAAAAAGGGGTTTTTACCACTTATAAAGAGAAAAACC
CTATCGCTTTGAAAACTTAA

Upstream 100 bases:

>100_bases
TAATGATACCGCTTAATAACCGCACTAACGGATAGATTGTCTCTCCTTTTATGTTAAAATAGAAAAATTTGTCATAAATT
TTAGGTGGTGTGTGGTTTAA

Downstream 100 bases:

>100_bases
CCAATAAATAAGGTAAAATTAAGACATGCATGCAGAATTTTTCACTTTCGCGCTCATCATGCTTTTAATTGTGATGGCCC
CTTATATGTCTAGAATCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLKKKIDLHKDSIRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLFGFGAASIVG
YFLGQNKTHRARLVFSSVFYFVAISAFILSMALLPFSETIARFFGSNDALLGMSKRYIEIILMGAVFMVLHPLADVFVVN
DKRPVLAMVAMLIGSLANIFFNYLFIFVLKVGVQGSAIATVIGHAIGVLVLMQHFWFKKGQLYFIKRFSLSSVISSAKSG
VPQSTAEFSASVMILLFNTAIMHTAGERFVSVYGIVMYNAIIFFTTLFAISQGIQPIASFSYGARNLERVKEVFVFGLKA
AFCIGVVFYGVYYFLDEFLIKLYLQPSEQDPLFMQETKRAMNIYYVGYVFLGMTLLCAVFFQSIQRAKSSFIITLSHTLG
FIVILLPILSHFYGINGVWVTYPIAQFLAFLVALGVTYYEIKKGVFTTYKEKNPIALKT

Sequences:

>Translated_459_residues
MLKKKIDLHKDSIRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLFGFGAASIVG
YFLGQNKTHRARLVFSSVFYFVAISAFILSMALLPFSETIARFFGSNDALLGMSKRYIEIILMGAVFMVLHPLADVFVVN
DKRPVLAMVAMLIGSLANIFFNYLFIFVLKVGVQGSAIATVIGHAIGVLVLMQHFWFKKGQLYFIKRFSLSSVISSAKSG
VPQSTAEFSASVMILLFNTAIMHTAGERFVSVYGIVMYNAIIFFTTLFAISQGIQPIASFSYGARNLERVKEVFVFGLKA
AFCIGVVFYGVYYFLDEFLIKLYLQPSEQDPLFMQETKRAMNIYYVGYVFLGMTLLCAVFFQSIQRAKSSFIITLSHTLG
FIVILLPILSHFYGINGVWVTYPIAQFLAFLVALGVTYYEIKKGVFTTYKEKNPIALKT
>Mature_459_residues
MLKKKIDLHKDSIRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLFGFGAASIVG
YFLGQNKTHRARLVFSSVFYFVAISAFILSMALLPFSETIARFFGSNDALLGMSKRYIEIILMGAVFMVLHPLADVFVVN
DKRPVLAMVAMLIGSLANIFFNYLFIFVLKVGVQGSAIATVIGHAIGVLVLMQHFWFKKGQLYFIKRFSLSSVISSAKSG
VPQSTAEFSASVMILLFNTAIMHTAGERFVSVYGIVMYNAIIFFTTLFAISQGIQPIASFSYGARNLERVKEVFVFGLKA
AFCIGVVFYGVYYFLDEFLIKLYLQPSEQDPLFMQETKRAMNIYYVGYVFLGMTLLCAVFFQSIQRAKSSFIITLSHTLG
FIVILLPILSHFYGINGVWVTYPIAQFLAFLVALGVTYYEIKKGVFTTYKEKNPIALKT

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51507; Mature: 51507

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCHHHHHHHCHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCHHHHHHHCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]