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The map label for this gene is deoD [H]

Identifier: 108563542

GI number: 108563542

Start: 1176813

End: 1177514

Strand: Reverse

Name: deoD [H]

Synonym: HPAG1_1117

Alternate gene names: 108563542

Gene position: 1177514-1176813 (Counterclockwise)

Preceding gene: 108563543

Following gene: 108563540

Centisome position: 73.76

GC content: 41.88

Gene sequence:

>702_bases
ATGACCCCTCACATTAACGCCAAAATCGGCGATTTTTATCCTCAATGCCTTTTATGCGGCGATCCCTTAAGGGTGAGCTA
CATTGCGAAAAAATTCTTACAAGACGCCAAAGAGATCACGAATGTGCGTAACATGCTAGGCTTTAGCGGGAAGTATAAGG
GTAAGGGGATTTCTTTAATGGGGCATGGCATGGGCATTGCGTCATGCACGATTTATGTAACCGAACTCATTAAAACCTAT
CAGGTTAAAGAGCTTTTAAGGATTGGCACTTGCGGGGCGATTAGCCCAAAAGTTGGCCTGAAAGACATTATCATGGCAAT
GGGAGCTTCAACGGATTCTAAAACCAATCGGGTGCGTTTTTTAAACCACGATTTGAGCGCAACGCCTGATTTTGAATTGA
GTTTAAGAGCGTATCAAACAGCAAAGCGTTTGGGCATTGATTTGAAAGTGGGTAATGTTTTTTCAAGCGATTTTTTCTAT
TCTTTTGAAACGCATGCCTTTGATTTAATGGCCCAATACAACCACTTGGCTATTGAAATGGAAGCGGCAGGGTTATACGC
CACGGCGATGGAATTGAGTGCTAAGGCTTTATGCTTATGCTCGGTTTCAGATCACTTAATCACTAAAGAAGCCTTAAGCC
CTAAAGAAAGGGTAGAAAGCTTTGATAACATGATAATTTTGGCTTTAGAGATGATGAGTTAG

Upstream 100 bases:

>100_bases
AGAGCGAGTCGTTTGCGGATATTGGGCAAAGTATCGCTTATTTTTTAGGATTAAGCCCCTTAGATTATGGCAAAAACTTA
TTAAACTTTAAAGGACAACC

Downstream 100 bases:

>100_bases
CCTTTTTTGTTGCCCCCATAAGTTAAGGATAAGCTTTAAAGGAAAACCCTTAAAGCTAAAAGCCTTAAGGGAACTTTGGA
AAAACTAAAGCTATCGTTTT

Product: purine-nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLMGHGMGIASCTIYVTELIKTY
QVKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFY
SFETHAFDLMAQYNHLAIEMEAAGLYATAMELSAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS

Sequences:

>Translated_233_residues
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLMGHGMGIASCTIYVTELIKTY
QVKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFY
SFETHAFDLMAQYNHLAIEMEAAGLYATAMELSAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS
>Mature_232_residues
TPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLMGHGMGIASCTIYVTELIKTYQ
VKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYS
FETHAFDLMAQYNHLAIEMEAAGLYATAMELSAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=229, Percent_Identity=55.0218340611354, Blast_Score=280, Evalue=7e-77,
Organism=Escherichia coli, GI1790265, Length=190, Percent_Identity=28.4210526315789, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25761; Mature: 25630

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLM
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
GHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEE
LNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAQYNHLAIEM
EECCCCCCCCCEEEHHHHHHHHHHCCEEEECCEECCCEEEEHHHHHHHHHHHCCEEEEEE
EAAGLYATAMELSAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS
ECCCHHHHHHHHCCCEEEEEECCHHHHHHHHCCHHHHHHHHCCEEEEEEEECC
>Mature Secondary Structure 
TPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLM
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
GHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEE
LNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAQYNHLAIEM
EECCCCCCCCCEEEHHHHHHHHHHCCEEEECCEECCCEEEEHHHHHHHHHHHCCEEEEEE
EAAGLYATAMELSAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS
ECCCHHHHHHHHCCCEEEEEECCHHHHHHHHCCHHHHHHHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA