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The map label for this gene is yicO [C]

Identifier: 108563539

GI number: 108563539

Start: 1172668

End: 1173975

Strand: Reverse

Name: yicO [C]

Synonym: HPAG1_1114

Alternate gene names: 108563539

Gene position: 1173975-1172668 (Counterclockwise)

Preceding gene: 108563540

Following gene: 108563538

Centisome position: 73.54

GC content: 44.34

Gene sequence:

>1308_bases
ATGGGGTTTTTCAAGCTTAAAGAACACAACACTAACATCGCCACCGAGTTTAGAGCGGGTTTAACGACTTTTATCACCAT
GATTTACATCGTGCCATTAAACGCTCTTATCCTTTCTCACGCCAACATGCCTTATGAAGCCCTTTTAAGTGCAACGGCCA
TTATCACTATCTTATCGAGCGTGTTTAACGGGTTGTGGGCAAACACCCCCATCGCTATGAGCGTGGGCTTAGGGTTGTCA
GCTTATTTTAGCTTCGGGTTGGTTCAGGGGCTAAAACTCCCTTGGCAGAGCGCTTTAGGCATCGTAGCGCTCTCGGGAGC
GATTTTTGTGATCTTGTCTTTCACCAAATTTAGAAGTTGGGTCATGCGAAGTATTCCTAGCGATTTAAGGCGTGCGGTGA
GCGCGGGGATAGGGGCTTTTATCGCGTTTATTGGTCTTAAAGAAATGCATATTGTCGTTACCCATAAGGCTACGCTTGTA
ACCTTAGGCGATTTTGGCGATCCGCATGTGTTATTGGGGGTTGTGGGGATCATTCTAACTTTCGCGCTCTACACGCTCAA
AATCAGGGGTTCTTTCATTATAGCGGTCTTAATCACTTCCATTCTCGCATGGGTTTTAAAGCTAGCCCCTTACCCTAGCG
AATTTTTTTCCATGCCTGCTAGCATTAGCCCTATCGCCTTTCAATTAGACTTTAAAGGCATTTTTTTTGATGCGAGTGGG
GCTTTCACTTTAGCGTTAGTGCCAGTCATCATCACTTTTTTTGTAACCGATTTGTTTGATTCTTTAGGCACGCTTGCAGG
GATTGGCCACAAGACTGATTTTTTCAATGATGAAGAAAAAAATAAGGAATTGGAAAAGACTTTGGAAGCGGATGCGGTGG
CTTCTTTAGGGAGCGCGGTGGTGGGCGTTTCTACCACGACAGCTTTTATAGAGAGCGCGAGTGGGGTTGAAGAGGGGGGC
CGCACAGGGCTGACAGCGGTTTTTACCGGATTATTTTTTGTTTTAACGCTCTTTTGCTTGCCTCTTTTAAAAGCCATTCC
TAGCAATGCGATTTATCCGGTGCTAGTGGTAGTAGGGGTTTTGATGTTTAGCGTGTTAGAGGGGGTGAATTTTAAAGACA
TGGCCATTAGCGTTTCCACTTTTTTAACCGTGGTGATGATGCCCTTAACTTTCTCCATTGCCGATGGCTTAGCCTTTGGC
TTTTTGTCTTATAGTATCATCAAATTGGTTCAAAAAGACTTCAAAGCGCTCAATTCAGGCATCATCATTCTCTGCATCAT
TTCTGTTTCTGTATTTATCTTTCGTTAA

Upstream 100 bases:

>100_bases
AATCAAGCATCTTAAGGCAATTTAAAATAAAATAGCGCTAGCATGACTTAAAAGCCCCTTATTAAATTAATCTATACCAA
ATAGTAAGGAGTTATCTAAC

Downstream 100 bases:

>100_bases
GCTCTTTTTAAGGGGCTTTGCATTTTTTACTCATTTCATGCCTCTTTTTCTTTATTTAGACAGATTATTATCTTAAAATA
ATTGTAATATCATTATTATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MGFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSHANMPYEALLSATAIITILSSVFNGLWANTPIAMSVGLGLS
AYFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSWVMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLV
TLGDFGDPHVLLGVVGIILTFALYTLKIRGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASG
AFTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELEKTLEADAVASLGSAVVGVSTTTAFIESASGVEEGG
RTGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVVVGVLMFSVLEGVNFKDMAISVSTFLTVVMMPLTFSIADGLAFG
FLSYSIIKLVQKDFKALNSGIIILCIISVSVFIFR

Sequences:

>Translated_435_residues
MGFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSHANMPYEALLSATAIITILSSVFNGLWANTPIAMSVGLGLS
AYFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSWVMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLV
TLGDFGDPHVLLGVVGIILTFALYTLKIRGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASG
AFTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELEKTLEADAVASLGSAVVGVSTTTAFIESASGVEEGG
RTGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVVVGVLMFSVLEGVNFKDMAISVSTFLTVVMMPLTFSIADGLAFG
FLSYSIIKLVQKDFKALNSGIIILCIISVSVFIFR
>Mature_434_residues
GFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSHANMPYEALLSATAIITILSSVFNGLWANTPIAMSVGLGLSA
YFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSWVMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLVT
LGDFGDPHVLLGVVGIILTFALYTLKIRGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASGA
FTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELEKTLEADAVASLGSAVVGVSTTTAFIESASGVEEGGR
TGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVVVGVLMFSVLEGVNFKDMAISVSTFLTVVMMPLTFSIADGLAFGF
LSYSIIKLVQKDFKALNSGIIILCIISVSVFIFR

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=427, Percent_Identity=38.1733021077283, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1790150, Length=424, Percent_Identity=37.9716981132075, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI1790499, Length=432, Percent_Identity=30.787037037037, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI48994909, Length=424, Percent_Identity=29.9528301886792, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46776; Mature: 46645

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSHANMPYEALLSATAIITILSS
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VFNGLWANTPIAMSVGLGLSAYFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSW
HHHHHHCCCCHHEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLVTLGDFGDPHVLLGVVGIILT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEEEECCCCCHHHHHHHHHHHHH
FALYTLKIRGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEECEEEEECCC
AFTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELEKTLEADAVASLGSAV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
VGVSTTTAFIESASGVEEGGRTGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVVVGV
HCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LMFSVLEGVNFKDMAISVSTFLTVVMMPLTFSIADGLAFGFLSYSIIKLVQKDFKALNSG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IIILCIISVSVFIFR
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
GFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSHANMPYEALLSATAIITILSS
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VFNGLWANTPIAMSVGLGLSAYFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSW
HHHHHHCCCCHHEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLVTLGDFGDPHVLLGVVGIILT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEEEECCCCCHHHHHHHHHHHHH
FALYTLKIRGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEECEEEEECCC
AFTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELEKTLEADAVASLGSAV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
VGVSTTTAFIESASGVEEGGRTGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVVVGV
HCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LMFSVLEGVNFKDMAISVSTFLTVVMMPLTFSIADGLAFGFLSYSIIKLVQKDFKALNSG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IIILCIISVSVFIFR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]